Q8G078 (RL23_BRUSU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L23

Gene names

Name:	rplW
Ordered Locus Names:	BR1231, BS1330_I1227

Organism

Brucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]

Taxonomic identifier

204722 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	97 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome By similarity. HAMAP MF_01369_B
Subunit structure	Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome By similarity.
Sequence similarities	Belongs to the ribosomal protein L23P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	nucleotide binding Inferred from electronic annotation. Source: InterPro rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 97	97	50S ribosomal protein L23 HAMAP MF_01369_B		PRO_0000272718

Sequences

	Sequence		Length	Mass (Da)
	Q8G078 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: A485EE3886022FA3	FASTA	97	10,535
	10 20 30 40 50 60 MTDLRHYDVI VSPVITEKST MVSEHNQVVF NVARKATKPE IKAAVEALFG VKVTAVNTAV 70 80 90 RKGKVKRFRG LVGRQSDVKK AIVTLAEGQS IDVSTGL

References

[1]

"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts." Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed: 12271122] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.

[2]

"Revised genome sequence of Brucella suis 1330." Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R. J. Bacteriol. 193:6410-6410(2011) [PubMed: 22038969] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014291 Genomic DNA. Translation: AAN30150.1. CP002997 Genomic DNA. Translation: AEM18568.1.
RefSeq	NP_698235.1. NC_004310.3.
3D structure databases
HSSP	HSSP built from PDB template 1N88 based on UniProtKB Q9RA57.
ProteinModelPortal	Q8G078.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1166907.
GenomeReviews	Gene locus BR1231 in contig AE014291_GR.
KEGG	bms:BR1231.
NMPDR	fig|204722.1.peg.1192.
PATRIC	17790799. VBIBruSui107850_1253.
TIGR	BR1231.
Phylogenomic databases
HOGENOM	HBG439330.
OMA	WKKAYVS.
PhylomeDB	Q8G078.
ProtClustDB	PRK05738.
Enzyme and pathway databases
BioCyc	BSUI204722:BR_1231-MONOMER.
Family and domain databases
HAMAP	MF_01369_B. Ribosomal_L23_B. [Tree]
InterPro	IPR012677. Nucleotide-bd_a/b_plait. IPR012678. Ribosomal_L23/L15e_core_dom. IPR013025. Ribosomal_L25/23. [Graphical view]
Gene3D	G3DSA:3.30.70.330. a_b_plait_nuc_bd. 1 hit.
KO	K02892.
Pfam	PF00276. Ribosomal_L23. 1 hit. [Graphical view]
SUPFAM	SSF54189. L23_L15e_core. 1 hit.
PROSITE	PS00050. RIBOSOMAL_L23. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL23_BRUSU

Accession

Primary (citable) accession number: Q8G078
Secondary accession number(s): G0KAF2

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 23, 2007
Last sequence update:	March 1, 2003
Last modified:	January 25, 2012
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program