Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8G077

- RL4_BRUSU

UniProt

Q8G077 - RL4_BRUSU

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

50S ribosomal protein L4

Gene

rplD

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.UniRule annotation
Forms part of the polypeptide exit tunnel.UniRule annotation

GO - Molecular functioni

  1. rRNA binding Source: UniProtKB-HAMAP
  2. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L4UniRule annotation
Gene namesi
Name:rplDUniRule annotation
Ordered Locus Names:BR1232, BS1330_I1228
OrganismiBrucella suis biovar 1 (strain 1330)
Taxonomic identifieri204722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000824: Chromosome I, UP000007104: Chromosome I

Subcellular locationi

GO - Cellular componenti

  1. ribosome Source: UniProtKB-KW
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 20620650S ribosomal protein L4PRO_0000129194Add
BLAST

Proteomic databases

PRIDEiQ8G077.

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit.UniRule annotation

Protein-protein interaction databases

STRINGi204722.BR1232.

Structurei

3D structure databases

ProteinModelPortaliQ8G077.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L4P family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0088.
HOGENOMiHOG000248767.
KOiK02926.
OMAiILNHECV.
OrthoDBiEOG6M0T9G.

Family and domain databases

Gene3Di3.40.1370.10. 1 hit.
HAMAPiMF_01328_B. Ribosomal_L4_B.
InterProiIPR002136. Ribosomal_L4/L1e.
IPR013005. Ribosomal_L4/L1e_bac-type.
IPR023574. Ribosomal_L4_dom.
[Graphical view]
PANTHERiPTHR10746. PTHR10746. 1 hit.
PfamiPF00573. Ribosomal_L4. 1 hit.
[Graphical view]
SUPFAMiSSF52166. SSF52166. 1 hit.
TIGRFAMsiTIGR03953. rplD_bact. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8G077-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDLTITTLEG KDAGKVKLNE EIFGLDPRDD ILQRVVRWQL ARRQQGSHKA
60 70 80 90 100
QGRGDVSRTG SKMYKQKGTG RARHHSARAP QFRGGGQAHG PVVRNHDHDL
110 120 130 140 150
PKKVRALGLR HALSAKAKAS DLIIIDDLAS ADAKTKQLVS QFAKLGLENA
160 170 180 190 200
LLIGGAEIDA NFQRAASNIP NIDVLPVQGI NVYDILRRGK LVLSKAAVEA

LEERFK
Length:206
Mass (Da):22,561
Last modified:March 1, 2003 - v1
Checksum:i1CE73FA611BD2557
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ289570 Genomic DNA. Translation: ABB91848.1.
AE014291 Genomic DNA. Translation: AAN30151.1.
CP002997 Genomic DNA. Translation: AEM18569.1.
RefSeqiNP_698236.1. NC_004310.3.
YP_005616061.1. NC_017251.1.

Genome annotation databases

EnsemblBacteriaiAAN30151; AAN30151; BR1232.
AEM18569; AEM18569; BS1330_I1228.
GeneIDi1166908.
12138261.
KEGGibms:BR1232.
bsi:BS1330_I1228.
PATRICi17790801. VBIBruSui107850_1254.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ289570 Genomic DNA. Translation: ABB91848.1 .
AE014291 Genomic DNA. Translation: AAN30151.1 .
CP002997 Genomic DNA. Translation: AEM18569.1 .
RefSeqi NP_698236.1. NC_004310.3.
YP_005616061.1. NC_017251.1.

3D structure databases

ProteinModelPortali Q8G077.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 204722.BR1232.

Proteomic databases

PRIDEi Q8G077.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN30151 ; AAN30151 ; BR1232 .
AEM18569 ; AEM18569 ; BS1330_I1228 .
GeneIDi 1166908.
12138261.
KEGGi bms:BR1232.
bsi:BS1330_I1228.
PATRICi 17790801. VBIBruSui107850_1254.

Phylogenomic databases

eggNOGi COG0088.
HOGENOMi HOG000248767.
KOi K02926.
OMAi ILNHECV.
OrthoDBi EOG6M0T9G.

Family and domain databases

Gene3Di 3.40.1370.10. 1 hit.
HAMAPi MF_01328_B. Ribosomal_L4_B.
InterProi IPR002136. Ribosomal_L4/L1e.
IPR013005. Ribosomal_L4/L1e_bac-type.
IPR023574. Ribosomal_L4_dom.
[Graphical view ]
PANTHERi PTHR10746. PTHR10746. 1 hit.
Pfami PF00573. Ribosomal_L4. 1 hit.
[Graphical view ]
SUPFAMi SSF52166. SSF52166. 1 hit.
TIGRFAMsi TIGR03953. rplD_bact. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Intrinsic and selected resistance to antibiotics binding the ribosome: analyses of Brucella 23S rrn, L4, L22, EF-Tu1, EF-Tu2, efflux and phylogenetic implications."
    Halling S.M., Jensen A.E.
    BMC Microbiol. 6:84-84(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 1330.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.

Entry informationi

Entry nameiRL4_BRUSU
AccessioniPrimary (citable) accession number: Q8G077
Secondary accession number(s): Q072A6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: March 1, 2003
Last modified: October 1, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella suis
    Brucella suis (strain 1330): entries and gene names
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3