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Protein

Elongation factor G

Gene

fusA

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi17 – 24GTPUniRule annotation8
Nucleotide bindingi86 – 90GTPUniRule annotation5
Nucleotide bindingi140 – 143GTPUniRule annotation4

GO - Molecular functioni

Keywordsi

Molecular functionElongation factor
Biological processProtein biosynthesis
LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor GUniRule annotation
Short name:
EF-GUniRule annotation
Gene namesi
Name:fusAUniRule annotation
Ordered Locus Names:BR1236, BS1330_I1232
OrganismiBrucella suis biovar 1 (strain 1330)
Taxonomic identifieri204722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000007104 Componenti: Chromosome I

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000910891 – 694Elongation factor GAdd BLAST694

Structurei

3D structure databases

ProteinModelPortaliQ8G075.
SMRiQ8G075.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini8 – 287tr-type GAdd BLAST280

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000231585.
KOiK02355.
OMAiISRIYQM.

Family and domain databases

CDDicd16262. EFG_III. 1 hit.
cd01434. EFG_mtEFG1_IV. 1 hit.
cd03713. EFG_mtEFG_C. 1 hit.
Gene3Di3.30.230.10. 1 hit.
HAMAPiMF_00054_B. EF_G_EF_2_B. 1 hit.
InterProiView protein in InterPro
IPR009022. EFG_III.
IPR035647. EFG_III/V.
IPR035649. EFG_V.
IPR000640. EFG_V-like.
IPR004161. EFTu-like_2.
IPR031157. G_TR_CS.
IPR027417. P-loop_NTPase.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR004540. Transl_elong_EFG/EF2.
IPR005517. Transl_elong_EFG/EF2_IV.
PfamiView protein in Pfam
PF00679. EFG_C. 1 hit.
PF03764. EFG_IV. 1 hit.
PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PRINTSiPR00315. ELONGATNFCT.
SMARTiView protein in SMART
SM00838. EFG_C. 1 hit.
SM00889. EFG_IV. 1 hit.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF54211. SSF54211. 1 hit.
SSF54980. SSF54980. 2 hits.
TIGRFAMsiTIGR00484. EF-G. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiView protein in PROSITE
PS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8G075-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAREYKIEDY RNFGIMAHID AGKTTMTERI LFYTGKNHKI GETHDGASTM
60 70 80 90 100
DWMEQEQERG ITITSAATTT FWQGRDGKKR RFNIIDTPGH VDFTIEVERS
110 120 130 140 150
LRVLDGAIAL LDANAGVEPQ TETVWRQAEK YHVPRMVFVN KMDKIGADFY
160 170 180 190 200
RSVEMVGSRL GAVALPVQLP IGAENDFVGV VDLIEMKALT WDGTIGAPAT
210 220 230 240 250
VGEIPADMAD KAEEYREKLI ELAVEIDEAA MEAYLEGTMP TNDELRALIR
260 270 280 290 300
KGTIEVKFHP ILCGTAFKNR GVQPLLDAVV EFLPAPTDVP AIKGIDVKTE
310 320 330 340 350
TETTRESSDE APLSMLAFKI MNDPFVGSLT FARIYSGKLT KGVSLENTVK
360 370 380 390 400
GKRERIGRML QMHSNSREDI DEAFAGDIVA LAGLKETTTG DTLCDPLKPV
410 420 430 440 450
ILERMEFPDP VIEIAIEPKT KADQEKMGIA LNRLAAEDPS FRVKSDEESG
460 470 480 490 500
QTIIAGMGEL HLDILVDRMK REFKVEANVG APQVAYRESI TRAAEIDYTH
510 520 530 540 550
KKQSGGSGQF ARVKIIFEPH DGDDFIFESK IVGGSVPKEY IPGVQKGIES
560 570 580 590 600
VMGAGPLAGF PMLGVKATLI DGAYHDVDSS VLAFEIASRA AFREGAQKAG
610 620 630 640 650
AQLLEPIMKV EVVTPEDYVG DVIGDLNSRR GQISGTEARG IATVVNAMVP
660 670 680 690
LANMFGYVNS LRSMSQGRAQ YTMQFDHYEP VPTAVAQEIQ KKFA
Length:694
Mass (Da):76,265
Last modified:March 1, 2003 - v1
Checksum:i1EC9ABC88B769A59
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014291 Genomic DNA. Translation: AAN30155.1.
CP002997 Genomic DNA. Translation: AEM18573.1.
RefSeqiWP_004685700.1. NZ_KN046804.1.

Genome annotation databases

EnsemblBacteriaiAAN30155; AAN30155; BR1236.
AEM18573; AEM18573; BS1330_I1232.
KEGGibms:BR1236.
bsi:BS1330_I1232.
PATRICifig|204722.21.peg.3393.

Similar proteinsi

Entry informationi

Entry nameiEFG_BRUSU
AccessioniPrimary (citable) accession number: Q8G075
Secondary accession number(s): G0KAF7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 29, 2003
Last sequence update: March 1, 2003
Last modified: August 30, 2017
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella suis
    Brucella suis (strain 1330): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families