SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8G075

- EFG_BRUSU

UniProt

Q8G075 - EFG_BRUSU

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Elongation factor G
Gene
fusA, BR1236, BS1330_I1232
Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi17 – 248GTP By similarity
Nucleotide bindingi86 – 905GTP By similarity
Nucleotide bindingi140 – 1434GTP By similarity

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-HAMAP
  2. GTPase activity Source: InterPro
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Elongation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor G
Short name:
EF-G
Gene namesi
Name:fusA
Ordered Locus Names:BR1236, BS1330_I1232
OrganismiBrucella suis biovar 1 (strain 1330)
Taxonomic identifieri204722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000824: Chromosome I, UP000007104: Chromosome I

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 694694Elongation factor GUniRule annotation
PRO_0000091089Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi204722.BR1236.

Structurei

3D structure databases

ProteinModelPortaliQ8G075.
SMRiQ8G075. Positions 4-691.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini8 – 287280tr-type G
Add
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0480.
HOGENOMiHOG000231585.
KOiK02355.
OMAiSGVQPQT.
OrthoDBiEOG6X6RBF.

Family and domain databases

Gene3Di3.30.230.10. 1 hit.
3.30.70.240. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00054_B. EF_G_EF_2_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR009022. EFG_III-V.
IPR000640. EFG_V.
IPR027417. P-loop_NTPase.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR004540. Transl_elong_EFG/EF2.
IPR005517. Transl_elong_EFG/EF2_IV.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view]
PfamiPF00679. EFG_C. 1 hit.
PF14492. EFG_II. 1 hit.
PF03764. EFG_IV. 1 hit.
PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SMARTiSM00838. EFG_C. 1 hit.
SM00889. EFG_IV. 1 hit.
[Graphical view]
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF54211. SSF54211. 1 hit.
SSF54980. SSF54980. 2 hits.
TIGRFAMsiTIGR00484. EF-G. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8G075-1 [UniParc]FASTAAdd to Basket

« Hide

MAREYKIEDY RNFGIMAHID AGKTTMTERI LFYTGKNHKI GETHDGASTM    50
DWMEQEQERG ITITSAATTT FWQGRDGKKR RFNIIDTPGH VDFTIEVERS 100
LRVLDGAIAL LDANAGVEPQ TETVWRQAEK YHVPRMVFVN KMDKIGADFY 150
RSVEMVGSRL GAVALPVQLP IGAENDFVGV VDLIEMKALT WDGTIGAPAT 200
VGEIPADMAD KAEEYREKLI ELAVEIDEAA MEAYLEGTMP TNDELRALIR 250
KGTIEVKFHP ILCGTAFKNR GVQPLLDAVV EFLPAPTDVP AIKGIDVKTE 300
TETTRESSDE APLSMLAFKI MNDPFVGSLT FARIYSGKLT KGVSLENTVK 350
GKRERIGRML QMHSNSREDI DEAFAGDIVA LAGLKETTTG DTLCDPLKPV 400
ILERMEFPDP VIEIAIEPKT KADQEKMGIA LNRLAAEDPS FRVKSDEESG 450
QTIIAGMGEL HLDILVDRMK REFKVEANVG APQVAYRESI TRAAEIDYTH 500
KKQSGGSGQF ARVKIIFEPH DGDDFIFESK IVGGSVPKEY IPGVQKGIES 550
VMGAGPLAGF PMLGVKATLI DGAYHDVDSS VLAFEIASRA AFREGAQKAG 600
AQLLEPIMKV EVVTPEDYVG DVIGDLNSRR GQISGTEARG IATVVNAMVP 650
LANMFGYVNS LRSMSQGRAQ YTMQFDHYEP VPTAVAQEIQ KKFA 694
Length:694
Mass (Da):76,265
Last modified:March 1, 2003 - v1
Checksum:i1EC9ABC88B769A59
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014291 Genomic DNA. Translation: AAN30155.1.
CP002997 Genomic DNA. Translation: AEM18573.1.
RefSeqiNP_698240.1. NC_004310.3.
YP_005616065.1. NC_017251.1.

Genome annotation databases

EnsemblBacteriaiAAN30155; AAN30155; BR1236.
AEM18573; AEM18573; BS1330_I1232.
GeneIDi1166912.
12138265.
KEGGibms:BR1236.
bsi:BS1330_I1232.
PATRICi17790809. VBIBruSui107850_1258.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014291 Genomic DNA. Translation: AAN30155.1 .
CP002997 Genomic DNA. Translation: AEM18573.1 .
RefSeqi NP_698240.1. NC_004310.3.
YP_005616065.1. NC_017251.1.

3D structure databases

ProteinModelPortali Q8G075.
SMRi Q8G075. Positions 4-691.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 204722.BR1236.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN30155 ; AAN30155 ; BR1236 .
AEM18573 ; AEM18573 ; BS1330_I1232 .
GeneIDi 1166912.
12138265.
KEGGi bms:BR1236.
bsi:BS1330_I1232.
PATRICi 17790809. VBIBruSui107850_1258.

Phylogenomic databases

eggNOGi COG0480.
HOGENOMi HOG000231585.
KOi K02355.
OMAi SGVQPQT.
OrthoDBi EOG6X6RBF.

Family and domain databases

Gene3Di 3.30.230.10. 1 hit.
3.30.70.240. 1 hit.
3.40.50.300. 1 hit.
HAMAPi MF_00054_B. EF_G_EF_2_B.
InterProi IPR000795. EF_GTP-bd_dom.
IPR009022. EFG_III-V.
IPR000640. EFG_V.
IPR027417. P-loop_NTPase.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR004540. Transl_elong_EFG/EF2.
IPR005517. Transl_elong_EFG/EF2_IV.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view ]
Pfami PF00679. EFG_C. 1 hit.
PF14492. EFG_II. 1 hit.
PF03764. EFG_IV. 1 hit.
PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
[Graphical view ]
PRINTSi PR00315. ELONGATNFCT.
SMARTi SM00838. EFG_C. 1 hit.
SM00889. EFG_IV. 1 hit.
[Graphical view ]
SUPFAMi SSF50447. SSF50447. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF54211. SSF54211. 1 hit.
SSF54980. SSF54980. 2 hits.
TIGRFAMsi TIGR00484. EF-G. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.

Entry informationi

Entry nameiEFG_BRUSU
AccessioniPrimary (citable) accession number: Q8G075
Secondary accession number(s): G0KAF7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 29, 2003
Last sequence update: March 1, 2003
Last modified: September 3, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella suis
    Brucella suis (strain 1330): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi