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Q8G069

- RPOB_BRUSU

UniProt

Q8G069 - RPOB_BRUSU

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Protein

DNA-directed RNA polymerase subunit beta

Gene
rpoB, BR1243, BS1330_I1239
Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates By similarity.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-HAMAP
  2. DNA-directed RNA polymerase activity Source: UniProtKB-HAMAP
  3. ribonucleoside binding Source: InterPro

GO - Biological processi

  1. transcription, DNA-templated Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit beta (EC:2.7.7.6)
Short name:
RNAP subunit beta
Alternative name(s):
RNA polymerase subunit beta
Transcriptase subunit beta
Gene namesi
Name:rpoB
Ordered Locus Names:BR1243, BS1330_I1239
OrganismiBrucella suis biovar 1 (strain 1330)
Taxonomic identifieri204722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000824: Chromosome I, UP000007104: Chromosome I

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 13771377DNA-directed RNA polymerase subunit betaUniRule annotationPRO_0000047871Add
BLAST

Interactioni

Subunit structurei

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription By similarity.

Protein-protein interaction databases

STRINGi204722.BR1243.

Structurei

3D structure databases

ProteinModelPortaliQ8G069.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0085.
HOGENOMiHOG000218612.
KOiK03043.
OMAiFPITDFS.
OrthoDBiEOG6M9DS6.

Family and domain databases

Gene3Di2.30.150.10. 1 hit.
2.40.270.10. 2 hits.
2.40.50.150. 2 hits.
3.90.1110.10. 2 hits.
HAMAPiMF_01321. RNApol_bact_RpoB.
InterProiIPR010243. DNA-dir_RNA_pol_bsu.
IPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view]
PANTHERiPTHR20856. PTHR20856. 1 hit.
PfamiPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 2 hits.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02013. rpoB. 1 hit.
PROSITEiPS01166. RNA_POL_BETA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8G069-1 [UniParc]FASTAAdd to Basket

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MAQTHSFNGR KRVRKFFGKI PEVAEMPNLI EVQKASYDQF LMVEEPSGGR     50
PDEGLQAVFK SVFPIQDFSG ASMLEFVRYE FDPPKFDVDE CRQRDLTYSA 100
PLKVTLRLIV FDIDEDTGAK SIKDIKEQDV YMGDMPLMTD NGTFIVNGTE 150
RVIVSQMHRS PGVFFDHDKG KTHSSGKLLF AARVIPYRGS WLDIEFDSKD 200
IVYARIDRRR KLPATTLLMA LGMDGEEILS TFYKTVTYTR DGDNWRIPYS 250
AERFKGMKII SDLVDADTGE AVLEAGKKLT ARAAKQLAEK GLKAIKATED 300
DLFGSYLAED VVNYATGEIY LEAGDEIDEK VLKTLIDTGE TEINVLDIDH 350
VNIGAYIRNT LAVDKNESRQ EALFDIYRVM RPGEPPTMDS AEAMFHSLFF 400
DSERYDLSAV GRVKMNMRLD LDAEDTVRVL RKEDILAVVK MLVELRDGRG 450
EIDDIDNLGN RRVRSVGELM ENQYRVGLLR MERAIKERMS SIEIDTVMPQ 500
DLINAKPAAA AVREFFGSSQ LSQFMDQTNP LSEITHKRRL SALGPGGLTR 550
ERAGFEVRDV HPTHYGRICP IETPEGPNIG LINSLATFAR VNKYGFIESP 600
YRKVVDGKVT NDVVYLSAME EAKHSVAQAN VELDEQGGFV DEFVICRHAG 650
EVMMAPRENV DLMDVSPKQL VSVAAALIPF LENDDANRAL MGSNMQRQAV 700
PLVRAEAPFV GTGMEPIVAR DSGAAIAARR GGIVDQVDAT RIVIRATEEL 750
DPSKSGVDIY RLQKFQRSNQ STCINQRPLV RVGDRIHKGD IIADGPSTDL 800
GDLALGRNVL VAFMPWNGYN YEDSILLSEK IVSDDVFTSI HIEEFEVAAR 850
DTKLGPEEIT RDIPNVSEEA LKNLDEAGIV YIGAEVHPGD ILVGKITPKG 900
ESPMTPEEKL LRAIFGEKAS DVRDTSMRMP PGTYGTVVEV RVFNRHGVEK 950
DERAMAIERE EIERLAKDRD DEQAILDRNV YGRLADMIDG KVAAAGPKGF 1000
KKGTTITREL MTEYPRSQWW QFAVEDEKLQ GELEALRSQY DDSKKLLEAR 1050
FMDKVEKVQR GDEMPPGVMK MVKVFVAVKR KIQPGDKMAG RHGNKGVVSR 1100
ILPVEDMPFL EDGTHADIVL NPLGVPSRMN VGQILETHLG WACAGMGKKI 1150
GELLDVYRKT ANIEPLRQTL EHIYPDNDRN EPVRSYDDDA ILMLANQVKR 1200
GVSIATPVFD GAVEADINAM LTDAGLATSG QSTLYDGRTG EPFDRQVTMG 1250
YIYMLKLHHL VDDKIHARSI GPYSLVTQQP LGGKAQFGGQ RFGEMEVWAL 1300
EAYGAAYTLQ EMLTVKSDDV AGRTKVYEAI VRGDDTFEAG IPESFNVLVK 1350
EMRSLGLNVE LDDTREAEQP ALPDAAE 1377
Length:1,377
Mass (Da):153,641
Last modified:March 1, 2003 - v1
Checksum:i5523F3E2A260F57F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014291 Genomic DNA. Translation: AAN30162.1.
CP002997 Genomic DNA. Translation: AEM18580.1.
RefSeqiNP_698247.1. NC_004310.3.
YP_005616072.1. NC_017251.1.

Genome annotation databases

EnsemblBacteriaiAAN30162; AAN30162; BR1243.
AEM18580; AEM18580; BS1330_I1239.
GeneIDi1166919.
12138272.
KEGGibms:BR1243.
bsi:BS1330_I1239.
PATRICi17790823. VBIBruSui107850_1265.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014291 Genomic DNA. Translation: AAN30162.1 .
CP002997 Genomic DNA. Translation: AEM18580.1 .
RefSeqi NP_698247.1. NC_004310.3.
YP_005616072.1. NC_017251.1.

3D structure databases

ProteinModelPortali Q8G069.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 204722.BR1243.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN30162 ; AAN30162 ; BR1243 .
AEM18580 ; AEM18580 ; BS1330_I1239 .
GeneIDi 1166919.
12138272.
KEGGi bms:BR1243.
bsi:BS1330_I1239.
PATRICi 17790823. VBIBruSui107850_1265.

Phylogenomic databases

eggNOGi COG0085.
HOGENOMi HOG000218612.
KOi K03043.
OMAi FPITDFS.
OrthoDBi EOG6M9DS6.

Miscellaneous databases

PROi Q8G069.

Family and domain databases

Gene3Di 2.30.150.10. 1 hit.
2.40.270.10. 2 hits.
2.40.50.150. 2 hits.
3.90.1110.10. 2 hits.
HAMAPi MF_01321. RNApol_bact_RpoB.
InterProi IPR010243. DNA-dir_RNA_pol_bsu.
IPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view ]
PANTHERi PTHR20856. PTHR20856. 1 hit.
Pfami PF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 2 hits.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR02013. rpoB. 1 hit.
PROSITEi PS01166. RNA_POL_BETA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.

Entry informationi

Entry nameiRPOB_BRUSU
AccessioniPrimary (citable) accession number: Q8G069
Secondary accession number(s): G0KAG4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: March 1, 2003
Last modified: June 11, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella suis
    Brucella suis (strain 1330): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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