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Q8FZV1 (CRCB1_BRUSU) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative fluoride ion transporter CrcB 1
Gene names
Name:crcB1
Ordered Locus Names:BR1369, BS1330_I1364
OrganismBrucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]
Taxonomic identifier204722 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length254 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Important for reducing fluoride concentration in the cell, thus reducing its toxicity By similarity. HAMAP-Rule MF_00454

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_00454.

Sequence similarities

Belongs to the CrcB (TC 9.B.71) family. [View classification]

Ontologies

Keywords
   Biological processTransport
   Cellular componentCell inner membrane
Cell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentintegral component of plasma membrane

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functioninorganic anion transmembrane transporter activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 254254Putative fluoride ion transporter CrcB 1 HAMAP-Rule MF_00454
PRO_0000110075

Regions

Transmembrane19 – 3921Helical; Potential
Transmembrane51 – 7121Helical; Potential
Transmembrane80 – 10021Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q8FZV1 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 9AD334D39C4A0987

FASTA25426,808
        10         20         30         40         50         60 
MTREFIMLMM PPLTDGFPLD ILVANVVACF LLGTVTALYA RKIHSRDVHT IIGMGMMGGV 

        70         80         90        100        110        120 
STFSSFAYGS VVLASASMSA FLIAAAYVTV SVVAGYVAVL AGMKFGEKSA DILHRYPPMA 

       130        140        150        160        170        180 
SIIDSGLVTV ESRHSVAETI ERVAAKAKSM GMNVFTRVDH GAGAKEAGLG LPPTELIIFG 

       190        200        210        220        230        240 
NPQNGTVLMQ DKRTIGLDLP IRALAWEDGS GKVWLTVNDP AWLAQRHSLG LSSDVAIKAM 

       250 
VTGTGTVTKY AAGD 

« Hide

References

[1]"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts."
Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. expand/collapse author list , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M.
Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.
[2]"Revised genome sequence of Brucella suis 1330."
Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R.
J. Bacteriol. 193:6410-6410(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014291 Genomic DNA. Translation: AAN30283.1.
CP002997 Genomic DNA. Translation: AEM18700.1.
RefSeqNP_698368.1. NC_004310.3.
YP_005616192.1. NC_017251.1.

3D structure databases

ProteinModelPortalQ8FZV1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING204722.BR1369.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN30283; AAN30283; BR1369.
AEM18700; AEM18700; BS1330_I1364.
GeneID1167051.
12138403.
KEGGbms:BR1369.
bsi:BS1330_I1364.
PATRIC17791089. VBIBruSui107850_1391.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3439.
HOGENOMHOG000289132.
OMAIIGMGMM.
OrthoDBEOG6VB726.

Family and domain databases

Gene3D3.30.310.70. 1 hit.
HAMAPMF_00454. CrcB.
InterProIPR003691. CrcB.
IPR005180. DUF302.
[Graphical view]
PfamPF02537. CRCB. 1 hit.
PF03625. DUF302. 1 hit.
[Graphical view]
SUPFAMSSF103247. SSF103247. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCRCB1_BRUSU
AccessionPrimary (citable) accession number: Q8FZV1
Secondary accession number(s): G0KB54
Entry history
Integrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: March 1, 2003
Last modified: April 16, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella suis

Brucella suis (strain 1330): entries and gene names