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Protein

Putative fluoride ion transporter CrcB 1

Gene

crcB1

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Important for reducing fluoride concentration in the cell, thus reducing its toxicity.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Putative fluoride ion transporter CrcB 1UniRule annotation
Gene namesi
Name:crcB1UniRule annotation
Ordered Locus Names:BR1369, BS1330_I1364
OrganismiBrucella suis biovar 1 (strain 1330)
Taxonomic identifieri204722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000007104 Componenti: Chromosome I

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei19 – 3921HelicalUniRule annotationAdd
BLAST
Transmembranei51 – 7121HelicalUniRule annotationAdd
BLAST
Transmembranei80 – 10021HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 254254Putative fluoride ion transporter CrcB 1PRO_0000110075Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ8FZV1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CrcB (TC 9.B.71) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG3439.
HOGENOMiHOG000289132.
OMAiIIGMGMM.
OrthoDBiEOG6VB726.

Family and domain databases

Gene3Di3.30.310.70. 1 hit.
HAMAPiMF_00454. CrcB.
InterProiIPR003691. CrcB.
IPR005180. DUF302.
[Graphical view]
PfamiPF02537. CRCB. 1 hit.
PF03625. DUF302. 1 hit.
[Graphical view]
SUPFAMiSSF103247. SSF103247. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8FZV1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTREFIMLMM PPLTDGFPLD ILVANVVACF LLGTVTALYA RKIHSRDVHT
60 70 80 90 100
IIGMGMMGGV STFSSFAYGS VVLASASMSA FLIAAAYVTV SVVAGYVAVL
110 120 130 140 150
AGMKFGEKSA DILHRYPPMA SIIDSGLVTV ESRHSVAETI ERVAAKAKSM
160 170 180 190 200
GMNVFTRVDH GAGAKEAGLG LPPTELIIFG NPQNGTVLMQ DKRTIGLDLP
210 220 230 240 250
IRALAWEDGS GKVWLTVNDP AWLAQRHSLG LSSDVAIKAM VTGTGTVTKY

AAGD
Length:254
Mass (Da):26,808
Last modified:March 1, 2003 - v1
Checksum:i9AD334D39C4A0987
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014291 Genomic DNA. Translation: AAN30283.1.
CP002997 Genomic DNA. Translation: AEM18700.1.
RefSeqiNP_698368.1. NC_004310.3.
WP_011069009.1. NC_017251.1.
YP_005616192.1. NC_017251.1.

Genome annotation databases

EnsemblBacteriaiAAN30283; AAN30283; BR1369.
AEM18700; AEM18700; BS1330_I1364.
KEGGibms:BR1369.
bsi:BS1330_I1364.
PATRICi17791089. VBIBruSui107850_1391.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014291 Genomic DNA. Translation: AAN30283.1.
CP002997 Genomic DNA. Translation: AEM18700.1.
RefSeqiNP_698368.1. NC_004310.3.
WP_011069009.1. NC_017251.1.
YP_005616192.1. NC_017251.1.

3D structure databases

ProteinModelPortaliQ8FZV1.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN30283; AAN30283; BR1369.
AEM18700; AEM18700; BS1330_I1364.
KEGGibms:BR1369.
bsi:BS1330_I1364.
PATRICi17791089. VBIBruSui107850_1391.

Phylogenomic databases

eggNOGiCOG3439.
HOGENOMiHOG000289132.
OMAiIIGMGMM.
OrthoDBiEOG6VB726.

Family and domain databases

Gene3Di3.30.310.70. 1 hit.
HAMAPiMF_00454. CrcB.
InterProiIPR003691. CrcB.
IPR005180. DUF302.
[Graphical view]
PfamiPF02537. CRCB. 1 hit.
PF03625. DUF302. 1 hit.
[Graphical view]
SUPFAMiSSF103247. SSF103247. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.

Entry informationi

Entry nameiCRCB1_BRUSU
AccessioniPrimary (citable) accession number: Q8FZV1
Secondary accession number(s): G0KB54
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: March 1, 2003
Last modified: June 24, 2015
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella suis
    Brucella suis (strain 1330): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.