Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8FYR3

- ATPA_BRUSU

UniProt

Q8FYR3 - ATPA_BRUSU

Protein

ATP synthase subunit alpha

Gene

atpA

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 91 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.UniRule annotation

    Catalytic activityi

    ATP + H2O + H+(In) = ADP + phosphate + H+(Out).UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei370 – 3701Required for activityUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi169 – 1768ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. proton-transporting ATPase activity, rotational mechanism Source: InterPro
    3. proton-transporting ATP synthase activity, rotational mechanism Source: UniProtKB-HAMAP

    GO - Biological processi

    1. ATP hydrolysis coupled proton transport Source: InterPro
    2. plasma membrane ATP synthesis coupled proton transport Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    ATP synthesis, Hydrogen ion transport, Ion transport, Transport

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    ATP synthase subunit alphaUniRule annotation (EC:3.6.3.14UniRule annotation)
    Alternative name(s):
    ATP synthase F1 sector subunit alphaUniRule annotation
    F-ATPase subunit alphaUniRule annotation
    Gene namesi
    Name:atpAUniRule annotation
    Ordered Locus Names:BR1801, BS1330_I1795
    OrganismiBrucella suis biovar 1 (strain 1330)
    Taxonomic identifieri204722 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000000824: Chromosome I, UP000007104: Chromosome I

    Subcellular locationi

    Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation

    GO - Cellular componenti

    1. plasma membrane Source: UniProtKB-SubCell
    2. proton-transporting ATP synthase complex, catalytic core F(1) Source: UniProtKB-KW

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, CF(1), Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 509509ATP synthase subunit alphaPRO_0000238216Add
    BLAST

    Proteomic databases

    PRIDEiQ8FYR3.

    Interactioni

    Subunit structurei

    F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a1, b2 and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF1 is attached to CF0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.UniRule annotation

    Protein-protein interaction databases

    STRINGi204722.BR1801.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8FYR3.
    SMRiQ8FYR3. Positions 24-501.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATPase alpha/beta chains family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0056.
    HOGENOMiHOG000130111.
    KOiK02111.
    OMAiIRPSEIS.
    OrthoDBiEOG67X1S1.

    Family and domain databases

    Gene3Di2.40.30.20. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPiMF_01346. ATP_synth_alpha_bact.
    InterProiIPR020003. ATPase_a/bsu_AS.
    IPR023366. ATPase_asu-like.
    IPR005294. ATPase_F1-cplx_asu.
    IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C.
    IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
    IPR004100. ATPase_F1_a/bsu_N.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF00006. ATP-synt_ab. 1 hit.
    PF00306. ATP-synt_ab_C. 1 hit.
    PF02874. ATP-synt_ab_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF47917. SSF47917. 1 hit.
    SSF50615. SSF50615. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00962. atpA. 1 hit.
    PROSITEiPS00152. ATPASE_ALPHA_BETA. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8FYR3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDIRAAEISA ILKEQIKNFG KEAEVSEVGQ VLSVGDGIAR VYGLDNVQAG    50
    EMVEFPGGIR GMALNLESDN VGVVIFGADR DIKEGDVVKR TGAIVDVPVG 100
    PELLGRVVDA LGNPIDGKGP IKAKERRRVD VKAPGIIPRK SVHEPMSTGL 150
    KAIDALIPVG RGQRELVIGD RQTGKTAIIL DTFLNQKPIH DNGPDKDKLY 200
    CVYVAVGQKR STVAQFVKVL EERGALEYSI VVAATASDPA PMQYLAPFAG 250
    CAMGEYFRDN GQHALIGYDD LSKQAVAYRQ MSLLLRRPPG REAYPGDVFY 300
    LHSRLLERAA KLNDENGAGS LTALPVIETQ GNDVSAFIPT NVISITDGQI 350
    FLETNLFYQG IRPAVNVGLS VSRVGSSAQI KAMKQVAGSI KGELAQHREM 400
    AAFAQFGSDL DAATQRLLNR GARLTELLKQ PQFSPLKTEE QVAVIYAGVN 450
    GYLDKLAVNQ VGKFEEGLLA SLRTEHKDVL EGIRNEKALT DDLKAKLKAA 500
    IDAFAKSFA 509
    Length:509
    Mass (Da):54,916
    Last modified:March 1, 2003 - v1
    Checksum:iD6ED094014D258B9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014291 Genomic DNA. Translation: AAN30696.1.
    CP002997 Genomic DNA. Translation: AEM19113.1.
    RefSeqiNP_698781.1. NC_004310.3.
    YP_005616605.1. NC_017251.1.

    Genome annotation databases

    EnsemblBacteriaiAAN30696; AAN30696; BR1801.
    AEM19113; AEM19113; BS1330_I1795.
    GeneIDi1167494.
    12137565.
    KEGGibms:BR1801.
    bsi:BS1330_I1795.
    PATRICi17791992. VBIBruSui107850_1829.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014291 Genomic DNA. Translation: AAN30696.1 .
    CP002997 Genomic DNA. Translation: AEM19113.1 .
    RefSeqi NP_698781.1. NC_004310.3.
    YP_005616605.1. NC_017251.1.

    3D structure databases

    ProteinModelPortali Q8FYR3.
    SMRi Q8FYR3. Positions 24-501.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 204722.BR1801.

    Proteomic databases

    PRIDEi Q8FYR3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAN30696 ; AAN30696 ; BR1801 .
    AEM19113 ; AEM19113 ; BS1330_I1795 .
    GeneIDi 1167494.
    12137565.
    KEGGi bms:BR1801.
    bsi:BS1330_I1795.
    PATRICi 17791992. VBIBruSui107850_1829.

    Phylogenomic databases

    eggNOGi COG0056.
    HOGENOMi HOG000130111.
    KOi K02111.
    OMAi IRPSEIS.
    OrthoDBi EOG67X1S1.

    Family and domain databases

    Gene3Di 2.40.30.20. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPi MF_01346. ATP_synth_alpha_bact.
    InterProi IPR020003. ATPase_a/bsu_AS.
    IPR023366. ATPase_asu-like.
    IPR005294. ATPase_F1-cplx_asu.
    IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C.
    IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
    IPR004100. ATPase_F1_a/bsu_N.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF00006. ATP-synt_ab. 1 hit.
    PF00306. ATP-synt_ab_C. 1 hit.
    PF02874. ATP-synt_ab_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47917. SSF47917. 1 hit.
    SSF50615. SSF50615. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00962. atpA. 1 hit.
    PROSITEi PS00152. ATPASE_ALPHA_BETA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 1330.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 1330.

    Entry informationi

    Entry nameiATPA_BRUSU
    AccessioniPrimary (citable) accession number: Q8FYR3
    Secondary accession number(s): G0K7D7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2006
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 91 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Brucella suis
      Brucella suis (strain 1330): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3