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Protein

Ribosomal RNA small subunit methyltransferase G

Gene

rsmG

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(527) in 16S rRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(527) in 16S rRNA.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei75S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation1
Binding sitei80S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation1
Binding sitei144S-adenosyl-L-methionineUniRule annotation1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA small subunit methyltransferase GUniRule annotation (EC:2.1.1.170UniRule annotation)
Alternative name(s):
16S rRNA 7-methylguanosine methyltransferaseUniRule annotation
Short name:
16S rRNA m7G methyltransferaseUniRule annotation
Gene namesi
Name:rsmGUniRule annotation
Synonyms:gidB
Ordered Locus Names:BR2060, BS1330_I2054
OrganismiBrucella suis biovar 1 (strain 1330)
Taxonomic identifieri204722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000007104 Componenti: Chromosome I

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001842301 – 213Ribosomal RNA small subunit methyltransferase GAdd BLAST213

Structurei

3D structure databases

ProteinModelPortaliQ8FY29.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni128 – 129S-adenosyl-L-methionine bindingUniRule annotation2

Sequence similaritiesi

Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000221015.
KOiK03501.
OMAiCLFLKGR.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_00074. 16SrRNA_methyltr_G. 1 hit.
InterProiIPR003682. rRNA_ssu_MeTfrase_G.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PfamiPF02527. GidB. 1 hit.
[Graphical view]
PIRSFiPIRSF003078. GidB. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00138. rsmG_gidB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8FY29-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSADIRFDSL KTIVPAVSRE TADRLIAFED LFRKWSKAIN LASPSTLADL
60 70 80 90 100
WNRHILDSAQ LFPLAKEATR WLDIGSGGGF PGIVTACFLA ERSGGCIDLV
110 120 130 140 150
ESAGKKAAFL RTAAGHLYVP ARVHSARIES MWEKIETPQV VTARALASLG
160 170 180 190 200
DLFTLAEPWL SDGAKALFQK GRDYQREIDE SRVGWSFDLV KHPSAIDQAS
210
VILEISNLRR KTD
Length:213
Mass (Da):23,499
Last modified:March 1, 2003 - v1
Checksum:iD81EAB78ED7B02F2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014291 Genomic DNA. Translation: AAN30950.1.
CP002997 Genomic DNA. Translation: AEM19367.1.
RefSeqiWP_006191026.1. NZ_KN046804.1.

Genome annotation databases

EnsemblBacteriaiAAN30950; AAN30950; BR2060.
AEM19367; AEM19367; BS1330_I2054.
KEGGibms:BR2060.
bsi:BS1330_I2054.
PATRICi17792547. VBIBruSui107850_2094.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014291 Genomic DNA. Translation: AAN30950.1.
CP002997 Genomic DNA. Translation: AEM19367.1.
RefSeqiWP_006191026.1. NZ_KN046804.1.

3D structure databases

ProteinModelPortaliQ8FY29.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN30950; AAN30950; BR2060.
AEM19367; AEM19367; BS1330_I2054.
KEGGibms:BR2060.
bsi:BS1330_I2054.
PATRICi17792547. VBIBruSui107850_2094.

Phylogenomic databases

HOGENOMiHOG000221015.
KOiK03501.
OMAiCLFLKGR.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_00074. 16SrRNA_methyltr_G. 1 hit.
InterProiIPR003682. rRNA_ssu_MeTfrase_G.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PfamiPF02527. GidB. 1 hit.
[Graphical view]
PIRSFiPIRSF003078. GidB. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00138. rsmG_gidB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRSMG_BRUSU
AccessioniPrimary (citable) accession number: Q8FY29
Secondary accession number(s): G0K908
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 25, 2003
Last sequence update: March 1, 2003
Last modified: September 7, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella suis
    Brucella suis (strain 1330): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.