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Q8FY19 (SECB_BRUSU) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein-export protein SecB
Gene names
Name:secB
Ordered Locus Names:BR2072, BS1330_I2066
OrganismBrucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]
Taxonomic identifier204722 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length163 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA By similarity. HAMAP-Rule MF_00821

Subunit structure

Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00821.

Sequence similarities

Belongs to the SecB family.

Ontologies

Keywords
   Biological processProtein transport
Translocation
Transport
   Cellular componentCytoplasm
   Molecular functionChaperone
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processprotein folding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

protein tetramerization

Inferred from electronic annotation. Source: InterPro

protein transport

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 163163Protein-export protein SecB HAMAP-Rule MF_00821
PRO_0000055355

Sequences

Sequence LengthMass (Da)Tools
Q8FY19 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 79D31398E1690A28

FASTA16317,878
        10         20         30         40         50         60 
MSDKAAGETK NGNGATTEPS LNILAQYVKD LSFESPGAPL SLRPREKAPS ININVNVNAN 

        70         80         90        100        110        120 
PLSETDFDVV LTLEAKAVDG KDILFNTELV YGGVFRIQGI PQEHMLPLLF IECPRLLFPF 

       130        140        150        160 
ARQIIADATR NGGYPPLMID PIDFAQMFQQ RMAEEQAKSA VKS 

« Hide

References

[1]"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts."
Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. expand/collapse author list , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M.
Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.
[2]"Revised genome sequence of Brucella suis 1330."
Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R.
J. Bacteriol. 193:6410-6410(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014291 Genomic DNA. Translation: AAN30962.1.
CP002997 Genomic DNA. Translation: AEM19379.1.
PIRAI3508.
RefSeqNP_699047.1. NC_004310.3.
YP_005616871.1. NC_017251.1.

3D structure databases

ProteinModelPortalQ8FY19.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING204722.BR2072.

Proteomic databases

PRIDEQ8FY19.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN30962; AAN30962; BR2072.
AEM19379; AEM19379; BS1330_I2066.
GeneID1167775.
12137855.
KEGGbms:BR2072.
bsi:BS1330_I2066.
PATRIC17792573. VBIBruSui107850_2107.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1952.
HOGENOMHOG000218193.
KOK03071.
OMAGFPPLMI.
OrthoDBEOG6DVJZZ.
ProtClustDBPRK05751.

Family and domain databases

Gene3D3.10.420.10. 1 hit.
HAMAPMF_00821. SecB.
InterProIPR003708. SecB.
[Graphical view]
PfamPF02556. SecB. 1 hit.
[Graphical view]
PRINTSPR01594. SECBCHAPRONE.
SUPFAMSSF54611. SSF54611. 1 hit.
TIGRFAMsTIGR00809. secB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSECB_BRUSU
AccessionPrimary (citable) accession number: Q8FY19
Secondary accession number(s): G0K920
Entry history
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: March 1, 2003
Last modified: February 19, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella suis

Brucella suis (strain 1330): entries and gene names