Q8FY19 (SECB_BRUSU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein-export protein SecB

Gene names

Name:	secB
Ordered Locus Names:	BR2072, BS1330_I2066

Organism

Brucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]

Taxonomic identifier

204722 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella suis

Protein attributes

Sequence length	163 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA By similarity. HAMAP-Rule MF_00821
Subunit structure	Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the SecB family.

Ontologies

Keywords
Biological process	Protein transport Translocation Transport
Cellular component	Cytoplasm
Molecular function	Chaperone
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	protein folding Inferred from electronic annotation. Source: HAMAP protein tetramerization Inferred from electronic annotation. Source: InterPro protein transport Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 163	163	Protein-export protein SecB HAMAP-Rule MF_00821		PRO_0000055355

Sequences

	Sequence		Length	Mass (Da)
	Q8FY19 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 79D31398E1690A28	FASTA	163	17,878
	10 20 30 40 50 60 MSDKAAGETK NGNGATTEPS LNILAQYVKD LSFESPGAPL SLRPREKAPS ININVNVNAN 70 80 90 100 110 120 PLSETDFDVV LTLEAKAVDG KDILFNTELV YGGVFRIQGI PQEHMLPLLF IECPRLLFPF 130 140 150 160 ARQIIADATR NGGYPPLMID PIDFAQMFQQ RMAEEQAKSA VKS

References

[1]

"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts." Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.

[2]

"Revised genome sequence of Brucella suis 1330." Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R. J. Bacteriol. 193:6410-6410(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014291 Genomic DNA. Translation: AAN30962.1. CP002997 Genomic DNA. Translation: AEM19379.1.
PIR	AI3508.
RefSeq	NP_699047.1. NC_004310.3. YP_005616871.1. NC_017251.1.
3D structure databases
ProteinModelPortal	Q8FY19.
ModBase	Search...
Protein-protein interaction databases
STRING	204722.BR2072.
Proteomic databases
PRIDE	Q8FY19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAN30962; AAN30962; BR2072. AEM19379; AEM19379; BS1330_I2066.
GeneID	1167775. 12137855.
KEGG	bms:BR2072. bsi:BS1330_I2066.
PATRIC	17792573. VBIBruSui107850_2107.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1952.
HOGENOM	HOG000218193.
KO	K03071.
OMA	GFPPLMI.
ProtClustDB	PRK05751.
Family and domain databases
Gene3D	3.10.420.10. 1 hit.
HAMAP	MF_00821. SecB.
InterPro	IPR003708. SecB. [Graphical view]
Pfam	PF02556. SecB. 1 hit. [Graphical view]
PRINTS	PR01594. SECBCHAPRONE.
SUPFAM	SSF54611. SecB. 1 hit.
TIGRFAMs	TIGR00809. secB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SECB_BRUSU

Accession

Primary (citable) accession number: Q8FY19
Secondary accession number(s): G0K920

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 20, 2005
Last sequence update:	March 1, 2003
Last modified:	May 1, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program