Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Chaperone protein DnaK

Gene

dnaK

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Acts as a chaperone.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Stress response

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein DnaKUniRule annotation
Alternative name(s):
HSP70UniRule annotation
Heat shock 70 kDa proteinUniRule annotation
Heat shock protein 70UniRule annotation
Gene namesi
Name:dnaKUniRule annotation
Ordered Locus Names:BR2125, BS1330_I2119
OrganismiBrucella suis biovar 1 (strain 1330)
Taxonomic identifieri204722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000007104 Componenti: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000784321 – 637Chaperone protein DnaKAdd BLAST637

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei198Phosphothreonine; by autocatalysisUniRule annotation1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiQ8FXX2.

Expressioni

Inductioni

By stress conditions e.g. heat shock.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ8FXX2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000228136.
KOiK04043.
OMAiEKMAPPQ.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK. 1 hit.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8FXX2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKVIGIDLG TTNSCVAVMD GKNAKVIENA EGARTTPSII AFTDGDERLA
60 70 80 90 100
GQPAKRQAVT NPEGTLFAVK RLIGRRYDDP MVTKDKDLVP YKIVKGDNGD
110 120 130 140 150
AWVEVHGKKY SPSQISAMIL QKMKETAESY LGETVTQAVI TVPAYFNDAQ
160 170 180 190 200
RQATKDAGKI AGLEVLRIIN EPTAAALAYG LDKSEGKTIA VYDLGGGTFD
210 220 230 240 250
VSVLEIGDGV FEVKSTNGDT FLGGEDFDIR LVEYLVAEFK KESGIDLKND
260 270 280 290 300
KLALQRLKEA AEKAKIELSS SQQTEINLPF ITADQTGPKH LAIKLSRAKF
310 320 330 340 350
ESLVDDLVQR TVEPCKAALK DAGLKAGEID EVVLVGGMTR MPKIQEVVKA
360 370 380 390 400
FFGKEPHKGV NPDEVVAMGA AIQGGVLQGD VKDVLLLDVT PLSLGIETLG
410 420 430 440 450
GVFTRLIERN TTIPTKKSQT FSTAEDNQSA VTIRVFQGER EMAADNKLLG
460 470 480 490 500
QFDLVGIPPA PRGVPQIEVT FDIDANGIVN VSAKDKGTGK EHQIRIQASG
510 520 530 540 550
GLTDADIEKM VKDAEANAEA DKKRRESVEA KNQAESLVHS TEKSLAEYGD
560 570 580 590 600
KVSADDKKAI EDAIAALKTS LEGEDAEDIK AKTQALAEVS MKLGQAMYEA
610 620 630
AQAAEGAGAE GGEQASSSKD DVVDADYEEI DDNKKSS
Length:637
Mass (Da):68,208
Last modified:March 1, 2003 - v1
Checksum:iC082ABDE53F2BBD5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014291 Genomic DNA. Translation: AAN31015.1.
CP002997 Genomic DNA. Translation: AEM19432.1.
RefSeqiWP_004691170.1. NZ_KN046804.1.

Genome annotation databases

EnsemblBacteriaiAAN31015; AAN31015; BR2125.
AEM19432; AEM19432; BS1330_I2119.
KEGGibms:BR2125.
bsi:BS1330_I2119.
PATRICi17792685. VBIBruSui107850_2163.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014291 Genomic DNA. Translation: AAN31015.1.
CP002997 Genomic DNA. Translation: AEM19432.1.
RefSeqiWP_004691170.1. NZ_KN046804.1.

3D structure databases

ProteinModelPortaliQ8FXX2.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ8FXX2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN31015; AAN31015; BR2125.
AEM19432; AEM19432; BS1330_I2119.
KEGGibms:BR2125.
bsi:BS1330_I2119.
PATRICi17792685. VBIBruSui107850_2163.

Phylogenomic databases

HOGENOMiHOG000228136.
KOiK04043.
OMAiEKMAPPQ.

Miscellaneous databases

PROiQ8FXX2.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK. 1 hit.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDNAK_BRUSU
AccessioniPrimary (citable) accession number: Q8FXX2
Secondary accession number(s): G0K973
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 19, 2003
Last sequence update: March 1, 2003
Last modified: October 5, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella suis
    Brucella suis (strain 1330): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.