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Protein

Apolipoprotein N-acyltransferase

Gene

lnt

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Transfers the fatty acyl group on membrane lipoproteins.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds Source: InterPro
  2. N-acyltransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. lipoprotein biosynthetic process Source: UniProtKB-HAMAP
  2. nitrogen compound metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Enzyme and pathway databases

UniPathwayiUPA00666.

Names & Taxonomyi

Protein namesi
Recommended name:
Apolipoprotein N-acyltransferaseUniRule annotation (EC:2.3.1.-UniRule annotation)
Short name:
ALP N-acyltransferaseUniRule annotation
Gene namesi
Name:lntUniRule annotation
Ordered Locus Names:BR2158, BS1330_I2152
OrganismiBrucella suis biovar 1 (strain 1330)
Taxonomic identifieri204722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000007104 Componenti: Chromosome I UP000000824 Componenti: Chromosome I

Subcellular locationi

Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei13 – 3018HelicalUniRule annotationAdd
BLAST
Transmembranei35 – 5218HelicalUniRule annotationAdd
BLAST
Transmembranei73 – 9523HelicalUniRule annotationAdd
BLAST
Transmembranei99 – 12123HelicalUniRule annotationAdd
BLAST
Transmembranei133 – 15523HelicalUniRule annotationAdd
BLAST
Transmembranei177 – 19923HelicalUniRule annotationAdd
BLAST
Transmembranei204 – 22623HelicalUniRule annotationAdd
BLAST
Transmembranei505 – 52723HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 532532Apolipoprotein N-acyltransferasePRO_0000178051Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi204722.BR2158.

Structurei

3D structure databases

ProteinModelPortaliQ8FXT9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini240 – 532293CN hydrolaseUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.UniRule annotation
Contains 1 CN hydrolase domain.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0815.
HOGENOMiHOG000264280.
KOiK03820.
OMAiFLAIVRM.
OrthoDBiEOG6VTJXM.

Family and domain databases

Gene3Di3.60.110.10. 1 hit.
HAMAPiMF_01148. Lnt.
InterProiIPR004563. Apolipo_AcylTrfase.
IPR003010. C-N_Hydrolase.
[Graphical view]
PfamiPF00795. CN_hydrolase. 1 hit.
[Graphical view]
SUPFAMiSSF56317. SSF56317. 1 hit.
TIGRFAMsiTIGR00546. lnt. 1 hit.
PROSITEiPS50263. CN_HYDROLASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8FXT9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIARLAGRII LLSGWRRALA AFLSGAFATL TQPPFDIFVA GFVSFPVLVW
60 70 80 90 100
LIDGAIARTD AGPLRRLLPA AKVGWWFGFG YFVSGLWWIG TALLVDADQF
110 120 130 140 150
AWALPLAVLG LPAFLALFYA FAAMIARLLW SDGLGRILAL AFGFALAEWL
160 170 180 190 200
RTFIFTGFPW NLIGYAAMPV PLLMQSVAVI GLVGMSALAV FVFAAPALLT
210 220 230 240 250
GGHFARTGIG LAIFLALAHV GFGAWTLSRA PAIVDENGPL AVRIVQPSIA
260 270 280 290 300
QAMKWDNAER RAIFDKLVGL TEEAPAEGKP RPDVIVWPET AIPYILESTP
310 320 330 340 350
QALAHIGDAL QEGQVLLAGA VREEKGADGG EPRYYNSIYT IDDRGRIVST
360 370 380 390 400
ADKVHLVPFG EYLPFESFLR GLGLQEVVEM PGGFTAGTTR HALAVKDGRS
410 420 430 440 450
FLPLICYEAI FPDELGYEGA GASAIINVTN DAWYGDTPGP YQHFRQAQVR
460 470 480 490 500
AVEQGLPLIR AANNGLSAIV NTYGRITGSL ALDAVGVVDS YLPSPRDPFW
510 520 530
GRPPGWIQTV LILLTLLAAS VGLILYSRRR FH
Length:532
Mass (Da):57,461
Last modified:March 1, 2003 - v1
Checksum:iBE5FF9DE257148B5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014291 Genomic DNA. Translation: AAN31048.1.
CP002997 Genomic DNA. Translation: AEM19465.1.
RefSeqiNP_699133.1. NC_004310.3.
YP_005616957.1. NC_017251.1.

Genome annotation databases

EnsemblBacteriaiAAN31048; AAN31048; BR2158.
AEM19465; AEM19465; BS1330_I2152.
KEGGibms:BR2158.
bsi:BS1330_I2152.
PATRICi17792749. VBIBruSui107850_2195.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014291 Genomic DNA. Translation: AAN31048.1.
CP002997 Genomic DNA. Translation: AEM19465.1.
RefSeqiNP_699133.1. NC_004310.3.
YP_005616957.1. NC_017251.1.

3D structure databases

ProteinModelPortaliQ8FXT9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi204722.BR2158.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN31048; AAN31048; BR2158.
AEM19465; AEM19465; BS1330_I2152.
KEGGibms:BR2158.
bsi:BS1330_I2152.
PATRICi17792749. VBIBruSui107850_2195.

Phylogenomic databases

eggNOGiCOG0815.
HOGENOMiHOG000264280.
KOiK03820.
OMAiFLAIVRM.
OrthoDBiEOG6VTJXM.

Enzyme and pathway databases

UniPathwayiUPA00666.

Family and domain databases

Gene3Di3.60.110.10. 1 hit.
HAMAPiMF_01148. Lnt.
InterProiIPR004563. Apolipo_AcylTrfase.
IPR003010. C-N_Hydrolase.
[Graphical view]
PfamiPF00795. CN_hydrolase. 1 hit.
[Graphical view]
SUPFAMiSSF56317. SSF56317. 1 hit.
TIGRFAMsiTIGR00546. lnt. 1 hit.
PROSITEiPS50263. CN_HYDROLASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.

Entry informationi

Entry nameiLNT_BRUSU
AccessioniPrimary (citable) accession number: Q8FXT9
Secondary accession number(s): G0K9I4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: March 1, 2003
Last modified: April 1, 2015
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella suis
    Brucella suis (strain 1330): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.