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Q8FXI7 (MODC_BRUSU) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Molybdenum import ATP-binding protein ModC

EC=3.6.3.29
Gene names
Name:modC
Ordered Locus Names:BRA0090, BS1330_II0090
OrganismBrucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]
Taxonomic identifier204722 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length359 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system By similarity.

Catalytic activity

ATP + H2O + molybdate(Out) = ADP + phosphate + molybdate(In).

Subunit structure

The complex is composed of two ATP-binding proteins (ModC), two transmembrane proteins (ModB) and a solute-binding protein (ModA) Potential.

Subcellular location

Cell inner membrane; Peripheral membrane protein By similarity.

Sequence similarities

Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family. [View classification]

Contains 1 ABC transporter domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 359359Molybdenum import ATP-binding protein ModC
PRO_0000092536

Regions

Domain1 – 233233ABC transporter
Nucleotide binding32 – 398ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q8FXI7 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 06DB5CFCA2CA8349

FASTA35938,859
        10         20         30         40         50         60 
MSGLTVSIRG RNGAFAIEAG FAAEGGVTAL FGHSGAGKTT LLKMIAGTLR PENGRIAVGD 

        70         80         90        100        110        120 
FTLFDAQKGI NLPPEKRCIG YVFQDARLFA YMSVKRNLTY ARWAGHRQAT RSFDEVVALL 

       130        140        150        160        170        180 
GIGHLLDRRP STLSGGERQR VAIGRALLSD PALLLLDEPL SSLDHARRQE ILPFIERLRD 

       190        200        210        220        230        240 
ESHVPIVYVS HEIDEVARLA DQIVLLSAGR VTASGAAADI FPLIDAESEG GGVLLEGIVS 

       250        260        270        280        290        300 
AYDERYKLAE IDLGGASFQL SDAGLKQTMH VRLRVRARDV SIARKIPEAI SIRNLLPVTV 

       310        320        330        340        350 
TGIERGEGPN AHVFLDFRGR RLGARLTRRS VDDLGLSVGD QVVALVKAVS VDRAAIREK 

« Hide

References

[1]"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts."
Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. expand/collapse author list , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M.
Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.
[2]"Revised genome sequence of Brucella suis 1330."
Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R.
J. Bacteriol. 193:6410-6410(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014292 Genomic DNA. Translation: AAN33300.1.
CP002998 Genomic DNA. Translation: AEM19580.1.
RefSeqNP_699295.1. NC_004311.2.
YP_005613806.1. NC_017250.1.

3D structure databases

ProteinModelPortalQ8FXI7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING204722.BRA0090.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN33300; AAN33300; BRA0090.
AEM19580; AEM19580; BS1330_II0090.
GeneID1164527.
12139524.
KEGGbms:BRA0090.
bsi:BS1330_II0090.
PATRIC17792985. VBIBruSui107850_2311.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG4148.
KOK02017.
OMAKTSCLRC.
OrthoDBEOG664CG0.
ProtClustDBCLSK898641.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
InterProIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR015852. ABC_transpr_ModC.
IPR008995. Mo/tungstate-bd_C_term_dom.
IPR011868. ModC_ABC_ATP-bd.
IPR027417. P-loop_NTPase.
IPR005116. Transp-assoc_OB_typ1.
[Graphical view]
PfamPF00005. ABC_tran. 1 hit.
PF03459. TOBE. 1 hit.
[Graphical view]
SMARTSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMSSF50331. SSF50331. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR02142. modC_ABC. 1 hit.
PROSITEPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
PS51241. MODC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMODC_BRUSU
AccessionPrimary (citable) accession number: Q8FXI7
Secondary accession number(s): G0KET6
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: March 1, 2003
Last modified: April 16, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella suis

Brucella suis (strain 1330): entries and gene names