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Protein

Molybdenum import ATP-binding protein ModC

Gene

modC

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system.UniRule annotation

Catalytic activityi

ATP + H2O + molybdate(Out) = ADP + phosphate + molybdate(In).UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi32 – 398ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. molybdate transmembrane-transporting ATPase activity Source: UniProtKB-HAMAP
  3. molybdenum ion transmembrane transporter activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Transport

Keywords - Ligandi

ATP-binding, Molybdenum, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Molybdenum import ATP-binding protein ModCUniRule annotation (EC:3.6.3.29UniRule annotation)
Gene namesi
Name:modCUniRule annotation
Ordered Locus Names:BRA0090, BS1330_II0090
OrganismiBrucella suis biovar 1 (strain 1330)
Taxonomic identifieri204722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000007104 Componenti: Chromosome II UP000000824 Componenti: Chromosome II

Subcellular locationi

Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

  1. ATP-binding cassette (ABC) transporter complex Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 359359Molybdenum import ATP-binding protein ModCPRO_0000092536Add
BLAST

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (ModC), two transmembrane proteins (ModB) and a solute-binding protein (ModA).UniRule annotation

Protein-protein interaction databases

STRINGi204722.BRA0090.

Structurei

3D structure databases

ProteinModelPortaliQ8FXI7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 233233ABC transporterUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family. [View classification]UniRule annotation
Contains 1 ABC transporter domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG4148.
KOiK02017.
OMAiFVSHAME.
OrthoDBiEOG664CG0.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR015852. ABC_transpr_ModC.
IPR008995. Mo/tungstate-bd_C_term_dom.
IPR011868. ModC_ABC_ATP-bd.
IPR027417. P-loop_NTPase.
IPR005116. Transp-assoc_OB_typ1.
[Graphical view]
PfamiPF00005. ABC_tran. 1 hit.
PF03459. TOBE. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF50331. SSF50331. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR02142. modC_ABC. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
PS51241. MODC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8FXI7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGLTVSIRG RNGAFAIEAG FAAEGGVTAL FGHSGAGKTT LLKMIAGTLR
60 70 80 90 100
PENGRIAVGD FTLFDAQKGI NLPPEKRCIG YVFQDARLFA YMSVKRNLTY
110 120 130 140 150
ARWAGHRQAT RSFDEVVALL GIGHLLDRRP STLSGGERQR VAIGRALLSD
160 170 180 190 200
PALLLLDEPL SSLDHARRQE ILPFIERLRD ESHVPIVYVS HEIDEVARLA
210 220 230 240 250
DQIVLLSAGR VTASGAAADI FPLIDAESEG GGVLLEGIVS AYDERYKLAE
260 270 280 290 300
IDLGGASFQL SDAGLKQTMH VRLRVRARDV SIARKIPEAI SIRNLLPVTV
310 320 330 340 350
TGIERGEGPN AHVFLDFRGR RLGARLTRRS VDDLGLSVGD QVVALVKAVS

VDRAAIREK
Length:359
Mass (Da):38,859
Last modified:February 28, 2003 - v1
Checksum:i06DB5CFCA2CA8349
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014292 Genomic DNA. Translation: AAN33300.1.
CP002998 Genomic DNA. Translation: AEM19580.1.
RefSeqiNP_699295.1. NC_004311.2.
YP_005613806.1. NC_017250.1.

Genome annotation databases

EnsemblBacteriaiAAN33300; AAN33300; BRA0090.
AEM19580; AEM19580; BS1330_II0090.
KEGGibms:BRA0090.
bsi:BS1330_II0090.
PATRICi17792985. VBIBruSui107850_2311.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014292 Genomic DNA. Translation: AAN33300.1.
CP002998 Genomic DNA. Translation: AEM19580.1.
RefSeqiNP_699295.1. NC_004311.2.
YP_005613806.1. NC_017250.1.

3D structure databases

ProteinModelPortaliQ8FXI7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi204722.BRA0090.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN33300; AAN33300; BRA0090.
AEM19580; AEM19580; BS1330_II0090.
KEGGibms:BRA0090.
bsi:BS1330_II0090.
PATRICi17792985. VBIBruSui107850_2311.

Phylogenomic databases

eggNOGiCOG4148.
KOiK02017.
OMAiFVSHAME.
OrthoDBiEOG664CG0.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR015852. ABC_transpr_ModC.
IPR008995. Mo/tungstate-bd_C_term_dom.
IPR011868. ModC_ABC_ATP-bd.
IPR027417. P-loop_NTPase.
IPR005116. Transp-assoc_OB_typ1.
[Graphical view]
PfamiPF00005. ABC_tran. 1 hit.
PF03459. TOBE. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF50331. SSF50331. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR02142. modC_ABC. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
PS51241. MODC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.

Entry informationi

Entry nameiMODC_BRUSU
AccessioniPrimary (citable) accession number: Q8FXI7
Secondary accession number(s): G0KET6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 31, 2005
Last sequence update: February 28, 2003
Last modified: March 31, 2015
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella suis
    Brucella suis (strain 1330): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.