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Q8FWV5

- GLSA_BRUSU

UniProt

Q8FWV5 - GLSA_BRUSU

Protein

Glutaminase

Gene

glsA

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei67 – 671SubstrateUniRule annotation
    Binding sitei118 – 1181SubstrateUniRule annotation
    Binding sitei162 – 1621SubstrateUniRule annotation
    Binding sitei169 – 1691SubstrateUniRule annotation
    Binding sitei193 – 1931SubstrateUniRule annotation
    Binding sitei245 – 2451SubstrateUniRule annotation
    Binding sitei263 – 2631Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. glutaminase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glutamine metabolic process Source: InterPro

    Keywords - Molecular functioni

    Hydrolase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
    Gene namesi
    Name:glsAUniRule annotation
    Ordered Locus Names:BRA0340, BS1330_II0337
    OrganismiBrucella suis biovar 1 (strain 1330)
    Taxonomic identifieri204722 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000000824: Chromosome II, UP000007104: Chromosome II

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 317317GlutaminasePRO_0000110599Add
    BLAST

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi204722.BRA0340.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8FWV5.
    SMRiQ8FWV5. Positions 5-309.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glutaminase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2066.
    HOGENOMiHOG000216890.
    KOiK01425.
    OMAiQCSVGVT.
    OrthoDBiEOG6N94BK.

    Family and domain databases

    Gene3Di3.40.710.10. 1 hit.
    HAMAPiMF_00313. Glutaminase.
    InterProiIPR012338. Beta-lactam/transpept-like.
    IPR015868. Glutaminase.
    [Graphical view]
    PANTHERiPTHR12544. PTHR12544. 1 hit.
    PfamiPF04960. Glutaminase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56601. SSF56601. 1 hit.
    TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8FWV5-1 [UniParc]FASTAAdd to Basket

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    MSSSSDAIKA ALEKGRAAGL SATGGKNADY IPFLASVPSD LFGLAVVTAD    50
    GQTFKTGDAD FAFAIESISK VFTLALVMEE IGPDSVREKV GADPTGLPFN 100
    SVIALELHNG KSLSPLVNAG AIATASLVPG DTADARWNNI LECQCGFAGR 150
    RLKLSNEVNQ SEQTTNFHNR AIAWLLYSAG TCYSDPMEAV DIYTRQCSTL 200
    VTATDLATMG ATLAAGGVNP ISGKRMVSAG NVAPILAEMT MEGLYTASGD 250
    WAYTVGLPGK SGVGGGIMAV VPGELAIAAF SPPLDPAGNS VKAMAAVAAV 300
    ADSLGHNLYT TRGKVSS 317
    Length:317
    Mass (Da):32,443
    Last modified:March 1, 2003 - v1
    Checksum:iA7B2A39A9A7EB02D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014292 Genomic DNA. Translation: AAN33538.1.
    CP002998 Genomic DNA. Translation: AEM19817.1.
    RefSeqiNP_699533.1. NC_004311.2.
    YP_005614043.1. NC_017250.1.

    Genome annotation databases

    EnsemblBacteriaiAAN33538; AAN33538; BRA0340.
    AEM19817; AEM19817; BS1330_II0337.
    GeneIDi1164778.
    12139772.
    KEGGibms:BRA0340.
    bsi:BS1330_II0337.
    PATRICi17793479. VBIBruSui107850_2556.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014292 Genomic DNA. Translation: AAN33538.1 .
    CP002998 Genomic DNA. Translation: AEM19817.1 .
    RefSeqi NP_699533.1. NC_004311.2.
    YP_005614043.1. NC_017250.1.

    3D structure databases

    ProteinModelPortali Q8FWV5.
    SMRi Q8FWV5. Positions 5-309.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 204722.BRA0340.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAN33538 ; AAN33538 ; BRA0340 .
    AEM19817 ; AEM19817 ; BS1330_II0337 .
    GeneIDi 1164778.
    12139772.
    KEGGi bms:BRA0340.
    bsi:BS1330_II0337.
    PATRICi 17793479. VBIBruSui107850_2556.

    Phylogenomic databases

    eggNOGi COG2066.
    HOGENOMi HOG000216890.
    KOi K01425.
    OMAi QCSVGVT.
    OrthoDBi EOG6N94BK.

    Family and domain databases

    Gene3Di 3.40.710.10. 1 hit.
    HAMAPi MF_00313. Glutaminase.
    InterProi IPR012338. Beta-lactam/transpept-like.
    IPR015868. Glutaminase.
    [Graphical view ]
    PANTHERi PTHR12544. PTHR12544. 1 hit.
    Pfami PF04960. Glutaminase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56601. SSF56601. 1 hit.
    TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 1330.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 1330.

    Entry informationi

    Entry nameiGLSA_BRUSU
    AccessioniPrimary (citable) accession number: Q8FWV5
    Secondary accession number(s): G0KC79
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 24, 2004
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Brucella suis
      Brucella suis (strain 1330): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3