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Protein

Probable acid stress chaperone HdeA

Gene

hdeA

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Required for optimal acid stress protection. Exhibits a chaperone-like activity only at low pH by suppressing non-specifically the aggregation of denaturated periplasmic proteins.UniRule annotation

GO - Biological processi

Keywordsi

Molecular functionChaperone

Names & Taxonomyi

Protein namesi
Recommended name:
Probable acid stress chaperone HdeAUniRule annotation
Gene namesi
Name:hdeAUniRule annotation
Ordered Locus Names:BRA0341, BS1330_II0338
OrganismiBrucella suis biovar 1 (strain 1330)
Taxonomic identifieri204722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000007104 Componenti: Chromosome II

Subcellular locationi

  • Periplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26UniRule annotationAdd BLAST26
ChainiPRO_000033863727 – 114Probable acid stress chaperone HdeAAdd BLAST88

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi46 ↔ 94UniRule annotation

Keywords - PTMi

Disulfide bond

Structurei

3D structure databases

ProteinModelPortaliQ8FWV4
SMRiQ8FWV4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the HdeA family.UniRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000125826
KOiK19777
OMAiFNEDITM

Family and domain databases

Gene3Di1.10.890.10, 1 hit
HAMAPiMF_00946 HdeA, 1 hit
InterProiView protein in InterPro
IPR024972 HdeA
IPR038303 HdeA/HdeB_sf
IPR036831 HdeA_sf
IPR010486 HNS-dep_expression_A/B
PfamiView protein in Pfam
PF06411 HdeA, 1 hit
PIRSFiPIRSF009564 HNS-dep_expression_A, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD065392 HNS-dep_expression_A, 1 hit
SUPFAMiSSF47752 SSF47752, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8FWV4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKALFNKNT ALAAVTILAL SGGAMAESAK THKTDMAKKK VSELTCEDFN
60 70 80 90 100
GLEESFKPTV VGWVVGFNKK GKEEDAVIDV DGIETVTPAI IEACKQEPKA
110
SFWKKAEAEL KKVF
Length:114
Mass (Da):12,362
Last modified:March 1, 2003 - v1
Checksum:iEA4B34293EF0B73E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014292 Genomic DNA Translation: AAN33539.1
CP002998 Genomic DNA Translation: AEM19818.1
RefSeqiWP_006191791.1, NZ_KN046805.1

Genome annotation databases

EnsemblBacteriaiAAN33539; AAN33539; BRA0341
AEM19818; AEM19818; BS1330_II0338
KEGGibms:BRA0341
bsi:BS1330_II0338
PATRICifig|204722.21.peg.161

Similar proteinsi

Entry informationi

Entry nameiHDEA_BRUSU
AccessioniPrimary (citable) accession number: Q8FWV4
Secondary accession number(s): G0KC80
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: March 1, 2003
Last modified: March 28, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health