Q8FW70 (Q8FW70_BRUSU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA topoisomerase IV subunit B EMBL AEM20057.1

Submitted name:
DNA topoisomerase IV, B subunit EMBL AAN33780.1
EC=5.99.1.- EMBL AAN33780.1

Gene names

Name:	parE EMBL AAN33780.1
Ordered Locus Names:	BRA0591, BS1330_II0586 EMBL AEM20057.1

Organism

Brucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]

Taxonomic identifier

204722 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	699 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the type II topoisomerase family. RuleBase RU000380

Ontologies

Keywords
Ligand	ATP-binding SAAS SAAS002288 RuleBase RU000380 Nucleotide-binding
Molecular function	Isomerase Topoisomerase SAAS SAAS002288 RuleBase RU000380
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA topological change Inferred from electronic annotation. Source: InterPro
Cellular component	chromosome Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA topoisomerase (ATP-hydrolyzing) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8FW70 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 6D3A37CFB3BC380C	FASTA	699	77,207
	10 20 30 40 50 60 MDDSNDLFSR VVNNARERQM ERQTGENTVA QPVVQPAPSA PKPVPAAAKA PPAASGGDDY 70 80 90 100 110 120 NASSIRVLEG LEPVRLRPGM YIGGTDEKAL HHLFAEVIDN SMDEAVAGHA NFIEVTVDKE 130 140 150 160 170 180 GFVTVSDNGR GIPVDKHPQV PGKSTLEVIM TKLHAGGKFD GKAYETSGGL HGVGVSVVNA 190 200 210 220 230 240 LSDVLEVEVA RNRRLYRQCF SRGIPQGGLE ELGEVHNRRG TRVRFHPDPE IFGKNAHFDP 250 260 270 280 290 300 HRLYRMARSK AYLFGGVEIR WNCDPSLLDP KKETPEKAVF HFPGGLKDYL EASLGKEHQV 310 320 330 340 350 360 TREVFAGRTE KQGGHGAVEW AVAWFGGDGF VHSYCNTIPT GDGGTHEAGL RIALTRGLKA 370 380 390 400 410 420 YAELTNNKRA SIITTDDVMV SAAGMLSVFI REPEFVGQTK DKLATVEAQR LVENAIRDPF 430 440 450 460 470 480 DHWLAASPQE ASRLLEWVID RADERLRRRQ EKETVRKSAT RKLRLPGKLA DCTQNAAAGA 490 500 510 520 530 540 ELFIVEGDSA GGSAKQARNR ANQAILPLRG KILNVASAGR EKLTANQQIA DLVQALGCGT 550 560 570 580 590 600 RKNYREDDLR YDRVIVMTDA DVDGAHIASL LITFFYQEMP ELIRNGHLYL AVPPLYRLSQ 610 620 630 640 650 660 GGKTAYARDD AHKEELLRTV FTGRGKIEIG RFKGLGEMRA DQLKETTMDP AKRTLLRVQV 670 680 690 DEEYGDETRN TVDDLMGTKP EARFRFIQDR AAFVEELDI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts." Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed: 12271122] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.
[2]	"Revised Genome Sequence of Brucella suis 1330." Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R. J. Bacteriol. 193:6410-6410(2011) Cited for: NUCLEOTIDE SEQUENCE. Strain: 1330 EMBL AEM20057.1.
[3]	"Revised genome sequence of Brucella suis 1330." Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R. J. Bacteriol. 193:6410-6410(2011) [PubMed: 22038969] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014292 Genomic DNA. Translation: AAN33780.1. CP002998 Genomic DNA. Translation: AEM20057.1.
RefSeq	NP_699775.1. NC_004311.2.
3D structure databases
HSSP	HSSP built from PDB template 1AJ6 based on UniProtKB P06982.
ProteinModelPortal	Q8FW70.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1165031.
GenomeReviews	Gene locus BRA0591 in contig AE014292_GR.
KEGG	bms:BRA0591.
NMPDR	fig|204722.1.peg.2684.
PATRIC	17793987. VBIBruSui107850_2807.
TIGR	BRA0591.
Phylogenomic databases
HOGENOM	HBG304889.
OMA	QARDKEF.
PhylomeDB	Q8FW70.
ProtClustDB	PRK05559.
Family and domain databases
InterPro	IPR003594. ATPase-like_ATP-bd. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. IPR001241. Topo_IIA. IPR013759. Topo_IIA_B/N_ab. IPR002288. Topo_IIA_B_C. IPR013506. Topo_IIA_bsu_dom2. IPR013760. Topo_IIA_cen. IPR018522. TopoIIA_CS. IPR005737. TopoIV_B_Gneg. IPR006171. Toprim_domain. [Graphical view]
Gene3D	G3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit. G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit. G3DSA:3.40.50.670. Topo_IIA_B/N_ab. 1 hit.
KO	K02622.
Pfam	PF00204. DNA_gyraseB. 1 hit. PF00986. DNA_gyraseB_C. 1 hit. PF02518. HATPase_c. 1 hit. PF01751. Toprim. 1 hit. [Graphical view]
PRINTS	PR00418. TPI2FAMILY.
SMART	SM00387. HATPase_c. 1 hit. SM00433. TOP2c. 1 hit. [Graphical view]
SUPFAM	SSF55874. ATP_bd_ATPase. 1 hit. SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit. SSF56719. Topo_IIA_cen. 1 hit.
TIGRFAMs	TIGR01055. ParE_Gneg. 1 hit.
PROSITE	PS00177. TOPOISOMERASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8FW70_BRUSU

Accession

Primary (citable) accession number: Q8FW70

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	January 25, 2012
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)