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Q8FW65 (RUVX_BRUSU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative Holliday junction resolvase

EC=3.1.-.-
Gene names
Ordered Locus Names:BRA0597, BS1330_II0592
OrganismBrucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]
Taxonomic identifier204722 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length162 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Could be a nuclease that resolves Holliday junction intermediates in genetic recombination By similarity. HAMAP-Rule MF_00651

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00651.

Sequence similarities

Belongs to the YqgF HJR family.

Ontologies

Keywords
   Biological processDNA damage
DNA recombination
DNA repair
   Cellular componentCytoplasm
   Molecular functionHydrolase
Nuclease
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processDNA recombination

Inferred from electronic annotation. Source: UniProtKB-KW

DNA repair

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionnuclease activity

Inferred from electronic annotation. Source: UniProtKB-KW

nucleic acid binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 162162Putative Holliday junction resolvase HAMAP-Rule MF_00651
PRO_0000172033

Sequences

Sequence LengthMass (Da)Tools
Q8FW65 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 75BBAF07458EBDB5

FASTA16217,526
        10         20         30         40         50         60 
MATAEIEEIP ALLKPGQTVA GLDLGTKTIG LAVSDLGLSF AHPRPVIKRV KFTIDAQVLL 

        70         80         90        100        110        120 
KALETDKVGV IVIGLPMNMD GTAGPRVQAT RAFVRTMQPL TDLPFVFWDE RLSTVAAERA 

       130        140        150        160 
LIGMDVSRGK RADRIDSAAA AFILQGALDR LHMMRRNDYD AG 

« Hide

References

[1]"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts."
Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. expand/collapse author list , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M.
Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.
[2]"Revised genome sequence of Brucella suis 1330."
Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R.
J. Bacteriol. 193:6410-6410(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014292 Genomic DNA. Translation: AAN33786.1.
CP002998 Genomic DNA. Translation: AEM20063.1.
RefSeqNP_699781.1. NC_004311.2.
YP_005614289.1. NC_017250.1.

3D structure databases

ProteinModelPortalQ8FW65.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING204722.BRA0597.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN33786; AAN33786; BRA0597.
AEM20063; AEM20063; BS1330_II0592.
GeneID1165037.
12138818.
KEGGbms:BRA0597.
bsi:BS1330_II0592.
PATRIC17794001. VBIBruSui107850_2814.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0816.
HOGENOMHOG000016953.
KOK07447.
OMAWTAQGIE.
OrthoDBEOG6N94FV.

Family and domain databases

Gene3D3.30.420.140. 1 hit.
HAMAPMF_00651. HJR_YqgF.
InterProIPR005227. Resolv_Hlld_junc_YqgF-like.
IPR012337. RNaseH-like_dom.
IPR006641. YqgF/RNaseH-like_dom.
[Graphical view]
PfamPF03652. UPF0081. 1 hit.
[Graphical view]
SMARTSM00732. YqgFc. 1 hit.
[Graphical view]
SUPFAMSSF53098. SSF53098. 1 hit.
TIGRFAMsTIGR00250. RNAse_H_YqgF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRUVX_BRUSU
AccessionPrimary (citable) accession number: Q8FW65
Secondary accession number(s): G0KCX5
Entry history
Integrated into UniProtKB/Swiss-Prot: June 16, 2003
Last sequence update: March 1, 2003
Last modified: May 14, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella suis

Brucella suis (strain 1330): entries and gene names