Q8FW65 (RUVX_BRUSU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative Holliday junction resolvase
EC=3.1.-.-

Gene names

Ordered Locus Names:

BRA0597, BS1330_II0592

Organism

Brucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]

Taxonomic identifier

204722 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella suis

Protein attributes

Sequence length	162 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination By similarity. HAMAP-Rule MF_00651
Subcellular location	Cytoplasm Potential HAMAP-Rule MF_00651.
Sequence similarities	Belongs to the YqgF HJR family.

Ontologies

Keywords
Biological process	DNA damage DNA recombination DNA repair
Cellular component	Cytoplasm
Molecular function	Hydrolase Nuclease
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA recombination Inferred from electronic annotation. Source: UniProtKB-KW DNA repair Inferred from electronic annotation. Source: UniProtKB-KW nucleic acid phosphodiester bond hydrolysis Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	nuclease activity Inferred from electronic annotation. Source: UniProtKB-KW nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 162	162	Putative Holliday junction resolvase HAMAP-Rule MF_00651		PRO_0000172033

Sequences

	Sequence		Length	Mass (Da)
	Q8FW65 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 75BBAF07458EBDB5	FASTA	162	17,526
	10 20 30 40 50 60 MATAEIEEIP ALLKPGQTVA GLDLGTKTIG LAVSDLGLSF AHPRPVIKRV KFTIDAQVLL 70 80 90 100 110 120 KALETDKVGV IVIGLPMNMD GTAGPRVQAT RAFVRTMQPL TDLPFVFWDE RLSTVAAERA 130 140 150 160 LIGMDVSRGK RADRIDSAAA AFILQGALDR LHMMRRNDYD AG

References

[1]

"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts." Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.

[2]

"Revised genome sequence of Brucella suis 1330." Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R. J. Bacteriol. 193:6410-6410(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014292 Genomic DNA. Translation: AAN33786.1. CP002998 Genomic DNA. Translation: AEM20063.1.
RefSeq	NP_699781.1. NC_004311.2. YP_005614289.1. NC_017250.1.
3D structure databases
ProteinModelPortal	Q8FW65.
ModBase	Search...
Protein-protein interaction databases
STRING	204722.BRA0597.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAN33786; AAN33786; BRA0597. AEM20063; AEM20063; BS1330_II0592.
GeneID	1165037. 12138818.
KEGG	bms:BRA0597. bsi:BS1330_II0592.
PATRIC	17794001. VBIBruSui107850_2814.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0816.
HOGENOM	HOG000016953.
KO	K07447.
OMA	KNMNGTV.
ProtClustDB	PRK00109.
Family and domain databases
Gene3D	3.30.420.140. 1 hit.
HAMAP	MF_00651. HJR_YqgF.
InterPro	IPR005227. Resolv_Hlld_junc_YqgF-like. IPR012337. RNaseH-like_dom. IPR006641. YqgF/RNaseH-like_dom. [Graphical view]
Pfam	PF03652. UPF0081. 1 hit. [Graphical view]
SMART	SM00732. YqgFc. 1 hit. [Graphical view]
SUPFAM	SSF53098. RNaseH_fold. 1 hit.
TIGRFAMs	TIGR00250. RNAse_H_YqgF. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RUVX_BRUSU

Accession

Primary (citable) accession number: Q8FW65
Secondary accession number(s): G0KCX5

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 16, 2003
Last sequence update:	March 1, 2003
Last modified:	May 29, 2013
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program