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Q8FW08 (UGPE_BRUSU) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
sn-glycerol-3-phosphate transport system permease protein UgpE
Gene names
Name:ugpE
Ordered Locus Names:BRA0657, BS1330_II0651
OrganismBrucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]
Taxonomic identifier204722 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length282 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Probably responsible for the translocation of the substrate across the membrane By similarity.

Subunit structure

The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB) Probable.

Subcellular location

Cell inner membrane; Multi-pass membrane protein Probable.

Sequence similarities

Belongs to the binding-protein-dependent transport system permease family.

Contains 1 ABC transmembrane type-1 domain.

Ontologies

Keywords
   Biological processSugar transport
Transport
   Cellular componentCell inner membrane
Cell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcarbohydrate transport

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functiontransporter activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 282282sn-glycerol-3-phosphate transport system permease protein UgpE
PRO_0000290140

Regions

Transmembrane14 – 3421Helical; Potential
Transmembrane86 – 10621Helical; Potential
Transmembrane112 – 13221Helical; Potential
Transmembrane146 – 16823Helical; Potential
Transmembrane201 – 22121Helical; Potential
Transmembrane248 – 26821Helical; Potential
Domain78 – 269192ABC transmembrane type-1

Sequences

Sequence LengthMass (Da)Tools
Q8FW08 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: C7C8FD2C3F698660

FASTA28231,992
        10         20         30         40         50         60 
MIEQRPVSNL IGHLILILGI IIVAFPIYYT FVASLMTSTQ IIRPPISLLP GDHLVENYRE 

        70         80         90        100        110        120 
AIFGGVERVV GVSLERLLWN SFVVAMAIAV GKIIISFMSA FAIVFFRFPM RMFFFWMIFI 

       130        140        150        160        170        180 
TLMLPVEVRI LPTYKVIVDL GMIDTYAGLT LPLMASATAT FLFRQFFLTI PGELVEAARI 

       190        200        210        220        230        240 
DNAGPFRFMR DILLPLSKTN IAALFVILSI YGWTQYLWPL LVTNDAKMNT IIIGLRRMVD 

       250        260        270        280 
WADASTSWNY VMVTAILAII PPILVVVLMQ RWFVKGLVET EK 

« Hide

References

[1]"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts."
Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. expand/collapse author list , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M.
Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.
[2]"Revised genome sequence of Brucella suis 1330."
Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R.
J. Bacteriol. 193:6410-6410(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014292 Genomic DNA. Translation: AAN33846.1.
CP002998 Genomic DNA. Translation: AEM20122.1.
RefSeqNP_699841.1. NC_004311.2.
YP_005614348.1. NC_017250.1.

3D structure databases

ProteinModelPortalQ8FW08.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING204722.BRA0657.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN33846; AAN33846; BRA0657.
AEM20122; AEM20122; BS1330_II0651.
GeneID1165099.
12138879.
KEGGbms:BRA0657.
bsi:BS1330_II0651.
PATRIC17794118. VBIBruSui107850_2870.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0395.
HOGENOMHOG000220524.
KOK05815.
OMAATDWNLL.
OrthoDBEOG693GR8.
ProtClustDBCLSK881849.

Family and domain databases

Gene3D1.10.3720.10. 1 hit.
InterProIPR000515. MetI-like.
[Graphical view]
PfamPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMSSF161098. SSF161098. 1 hit.
PROSITEPS50928. ABC_TM1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUGPE_BRUSU
AccessionPrimary (citable) accession number: Q8FW08
Secondary accession number(s): G0KD34
Entry history
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: March 1, 2003
Last modified: March 19, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella suis

Brucella suis (strain 1330): entries and gene names