Q8FVU0 (14KL_BRUSU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Lectin-like protein BA14k

Gene names

Ordered Locus Names:

BRA0735, BS1330_II0728

Organism

Brucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]

Taxonomic identifier

204722 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella suis

Protein attributes

Sequence length	147 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has immunoglobulin-binding and hemagglutination properties, and can bind to mannose. Essential for virulence. May be involved in LPS biosynthesis or polysaccharide transport By similarity.
Subcellular location	Cell membrane; Single-pass membrane protein Potential.
Sequence similarities	Belongs to the BA14k family.

Ontologies

Keywords
Biological process	Virulence
Cellular component	Cell membrane Membrane
Domain	Signal Transmembrane Transmembrane helix
Ligand	Lectin
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	pathogenesis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 26	26	Potential
	Chain	27 – 147	121	Lectin-like protein BA14k		PRO_0000361302
Regions
	Transmembrane	80 – 100	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	Q8FVU0 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 7CEE6F1FB2BB38DB	FASTA	147	16,823
	10 20 30 40 50 60 MNSFRKTCAG ALALIFGATS IVPTVAAPMN MDRPAINQNV IQARAHYRPQ NYNRGHRPGY 70 80 90 100 110 120 WHGHRGYRHY RHGYRRHNDG WWYPLAAFGA GAIIGGAISQ PRPVYRAPAG SPHVQWCYSR 130 140 YKSYRASDNT FQPYNGPRKQ CRSPYSR

References

[1]

"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts." Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.

[2]

"Revised genome sequence of Brucella suis 1330." Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R. J. Bacteriol. 193:6410-6410(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014292 Genomic DNA. Translation: AAN33917.1. CP002998 Genomic DNA. Translation: AEM20193.1.
PIR	AG3578.
RefSeq	NP_699912.1. NC_004311.2. YP_005614419.1. NC_017250.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	204722.BRA0735.
Proteomic databases
PRIDE	Q8FVU0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAN33917; AAN33917; BRA0735. AEM20193; AEM20193; BS1330_II0728.
GeneID	1165177. 12138956.
KEGG	bms:BRA0735. bsi:BS1330_II0728.
PATRIC	17794276. VBIBruSui107850_2949.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	NOG08130.
HOGENOM	HOG000274446.
OMA	YRPGYRP.
ProtClustDB	CLSK898873.
Family and domain databases
InterPro	IPR012413. BA14K. [Graphical view]
Pfam	PF07886. BA14K. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

14KL_BRUSU

Accession

Primary (citable) accession number: Q8FVU0
Secondary accession number(s): G0KDA5

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 20, 2009
Last sequence update:	March 1, 2003
Last modified:	May 1, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program