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Q8FVU0

- 14KL_BRUSU

UniProt

Q8FVU0 - 14KL_BRUSU

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Protein

Lectin-like protein BA14k

Gene

BRA0735

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Has immunoglobulin-binding and hemagglutination properties, and can bind to mannose. Essential for virulence. May be involved in LPS biosynthesis or polysaccharide transport (By similarity).By similarity

GO - Molecular functioni

  1. carbohydrate binding Source: UniProtKB-KW

GO - Biological processi

  1. pathogenesis Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Virulence

Keywords - Ligandi

Lectin

Names & Taxonomyi

Protein namesi
Recommended name:
Lectin-like protein BA14k
Gene namesi
Ordered Locus Names:BRA0735, BS1330_II0728
OrganismiBrucella suis biovar 1 (strain 1330)
Taxonomic identifieri204722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000824: Chromosome II, UP000007104: Chromosome II

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei80 – 10021HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2626Sequence AnalysisAdd
BLAST
Chaini27 – 147121Lectin-like protein BA14kPRO_0000361302Add
BLAST

Proteomic databases

PRIDEiQ8FVU0.

Interactioni

Protein-protein interaction databases

STRINGi204722.BRA0735.

Family & Domainsi

Sequence similaritiesi

Belongs to the BA14k family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG08130.
HOGENOMiHOG000274446.
OMAiHVAWCAN.
OrthoDBiEOG6358FW.

Family and domain databases

InterProiIPR012413. BA14K.
[Graphical view]
PfamiPF07886. BA14K. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8FVU0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNSFRKTCAG ALALIFGATS IVPTVAAPMN MDRPAINQNV IQARAHYRPQ
60 70 80 90 100
NYNRGHRPGY WHGHRGYRHY RHGYRRHNDG WWYPLAAFGA GAIIGGAISQ
110 120 130 140
PRPVYRAPAG SPHVQWCYSR YKSYRASDNT FQPYNGPRKQ CRSPYSR
Length:147
Mass (Da):16,823
Last modified:March 1, 2003 - v1
Checksum:i7CEE6F1FB2BB38DB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014292 Genomic DNA. Translation: AAN33917.1.
CP002998 Genomic DNA. Translation: AEM20193.1.
PIRiAG3578.
RefSeqiNP_699912.1. NC_004311.2.
YP_005614419.1. NC_017250.1.

Genome annotation databases

EnsemblBacteriaiAAN33917; AAN33917; BRA0735.
AEM20193; AEM20193; BS1330_II0728.
GeneIDi1165177.
12138956.
KEGGibms:BRA0735.
bsi:BS1330_II0728.
PATRICi17794276. VBIBruSui107850_2949.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014292 Genomic DNA. Translation: AAN33917.1 .
CP002998 Genomic DNA. Translation: AEM20193.1 .
PIRi AG3578.
RefSeqi NP_699912.1. NC_004311.2.
YP_005614419.1. NC_017250.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 204722.BRA0735.

Proteomic databases

PRIDEi Q8FVU0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN33917 ; AAN33917 ; BRA0735 .
AEM20193 ; AEM20193 ; BS1330_II0728 .
GeneIDi 1165177.
12138956.
KEGGi bms:BRA0735.
bsi:BS1330_II0728.
PATRICi 17794276. VBIBruSui107850_2949.

Phylogenomic databases

eggNOGi NOG08130.
HOGENOMi HOG000274446.
OMAi HVAWCAN.
OrthoDBi EOG6358FW.

Family and domain databases

InterProi IPR012413. BA14K.
[Graphical view ]
Pfami PF07886. BA14K. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.

Entry informationi

Entry namei14KL_BRUSU
AccessioniPrimary (citable) accession number: Q8FVU0
Secondary accession number(s): G0KDA5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: March 1, 2003
Last modified: October 29, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella suis
    Brucella suis (strain 1330): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3