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Protein

Uronate isomerase

Gene

uxaC

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:BRA0812, BS1330_II0805
OrganismiBrucella suis biovar 1 (strain 1330)
Taxonomic identifieri204722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000007104 Componenti: Chromosome II

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001727651 – 466Uronate isomeraseAdd BLAST466

Structurei

3D structure databases

ProteinModelPortaliQ8FVM4.
SMRiQ8FVM4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238114.
KOiK01812.
OMAiREMTTET.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8FVM4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALNPDRLFS AEPGTREIAR RLFASVEKLP IISPHGHTEP IWYARNEAFP
60 70 80 90 100
DPASLFVKPD HYITRMLYSQ GHSLESLGIA SRDGRPSETD ARKIWRLFAT
110 120 130 140 150
NWYLFRATPS RLWFEHAMET VFGITERLSQ ENADRIFDAI ADQLTQPHMR
160 170 180 190 200
PRALYDRFNI EAISTTDAAT DPLIYHDEVI ASGWHGRIIP AYRPDAAVDA
210 220 230 240 250
GRPDFASEVE KLVGVAGTPL TWQGYLDAHR NRREYFKRRG ATSSDHGHPT
260 270 280 290 300
AQTADLSAGD ASRLFDRVIK GNASTSDAEM FRAQMLTEMA RMSIDDGLVM
310 320 330 340 350
QIHPGSFRNH NPTVFERFGL DKGADIPRQT GFVDQLKPLL DAFGNDPRLT
360 370 380 390 400
VILFTLDETA YSRELAPLAG HYPALKLGPA WWFFDSPEGI LRYRKLTTET
410 420 430 440 450
AGFYNTVGFN DDTRAYLSIP ARHDMARRVD CAYLAGLVAD HRLEEDEAYE
460
VAHDLAYRLA KQTYKL
Length:466
Mass (Da):52,750
Last modified:March 1, 2003 - v1
Checksum:i7334C3D0A1927802
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014292 Genomic DNA. Translation: AAN33988.1.
CP002998 Genomic DNA. Translation: AEM20264.1.
RefSeqiWP_004687147.1. NZ_KN046805.1.

Genome annotation databases

EnsemblBacteriaiAAN33988; AAN33988; BRA0812.
AEM20264; AEM20264; BS1330_II0805.
KEGGibms:BRA0812.
bsi:BS1330_II0805.
PATRICi17794439. VBIBruSui107850_3030.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014292 Genomic DNA. Translation: AAN33988.1.
CP002998 Genomic DNA. Translation: AEM20264.1.
RefSeqiWP_004687147.1. NZ_KN046805.1.

3D structure databases

ProteinModelPortaliQ8FVM4.
SMRiQ8FVM4.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN33988; AAN33988; BRA0812.
AEM20264; AEM20264; BS1330_II0805.
KEGGibms:BRA0812.
bsi:BS1330_II0805.
PATRICi17794439. VBIBruSui107850_3030.

Phylogenomic databases

HOGENOMiHOG000238114.
KOiK01812.
OMAiREMTTET.

Enzyme and pathway databases

UniPathwayiUPA00246.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUXAC_BRUSU
AccessioniPrimary (citable) accession number: Q8FVM4
Secondary accession number(s): G0KDH6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2003
Last sequence update: March 1, 2003
Last modified: November 2, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella suis
    Brucella suis (strain 1330): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.