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Q8FVM2 (UXUA_BRUSU) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Mannonate dehydratase
EC=4.2.1.8
Alternative name(s):
D-mannonate hydrolase
Gene names
Name:uxuA
Ordered Locus Names:BRA0814, BS1330_II0807
OrganismBrucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]
Taxonomic identifier204722 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length401 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O. HAMAP MF_00106

Pathway

Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00106

Sequence similarities

Belongs to the mannonate dehydratase family.

Ontologies

Keywords
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglucuronate catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionmannonate dehydratase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 401401Mannonate dehydratase HAMAP MF_00106
PRO_0000170667

Sequences

Sequence LengthMass (Da)Tools
Q8FVM2 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 399192F5F46A0921

FASTA40144,445
        10         20         30         40         50         60 
MRQAWRWFGP EAGVPLDAVR QAGATDIVSA LHEVPIGQEW TSAQIVERKN LIESTPTGRH 

        70         80         90        100        110        120 
PLTWSVVESI PVSDDIKRSG KAARHDIGAW IASMEALARN DIKVICYNFM PVVDWCRTDL 

       130        140        150        160        170        180 
DYITSTGATA MRFDQDRFAA FDLHILQRKG AEKDYSEEDR IAARAIFEAM DETEIEQLIV 

       190        200        210        220        230        240 
NIASALPGST TEPLTIPAFR EKLETYASID AAHLRRNLVE FLEAVTPVAD SLGVKLTLHP 

       250        260        270        280        290        300 
DDPPRSLFGL PRIASTEADY AAIFAAVPAQ SNGMCFCTGS LGVRADNDLP AIARRFASRI 

       310        320        330        340        350        360 
HFSHLRATTR EGDGRTFHEA AHLEGDVDMV GILRILLEED RKRDAGQTII FRSDHGHRMM 

       370        380        390        400 
DDLEKKVTPG YPVIGRMRGL AELRGIITAL DACALEYDPN V

« Hide

References

[1]"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts."
Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. expand/collapse author list , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M.
Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed: 12271122] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.
[2]"Revised genome sequence of Brucella suis 1330."
Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R.
J. Bacteriol. 193:6410-6410(2011) [PubMed: 22038969] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE014292 Genomic DNA. Translation: AAN33990.1.
CP002998 Genomic DNA. Translation: AEM20266.1.
RefSeqNP_699985.1. NC_004311.2.

3D structure databases

ProteinModelPortalQ8FVM2.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1165256.
GenomeReviewsGene locus BRA0814 in contig AE014292_GR.
KEGGbms:BRA0814.
NMPDRfig|204722.1.peg.2894.
PATRIC17794443. VBIBruSui107850_3032.
TIGRBRA0814.

Phylogenomic databases

HOGENOMHBG585927.
OMAVHEEIKT.
PhylomeDBQ8FVM2.
ProtClustDBPRK03906.

Enzyme and pathway databases

BioCycBSUI204722:BR_A0814-MONOMER.

Family and domain databases

HAMAPMF_00106. UxuA.
[Tree]
InterProIPR004628. Man_deHydtase.
IPR013022. Xyl_isomerase-like_TIM-brl.
[Graphical view]
Gene3DG3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
KOK01686.
PfamPF03786. UxuA. 1 hit.
[Graphical view]
PIRSFPIRSF016049. Man_dehyd. 1 hit.
SUPFAMSSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMsTIGR00695. UxuA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUXUA_BRUSU
AccessionPrimary (citable) accession number: Q8FVM2
Secondary accession number(s): G0KDH8
Entry history
Integrated into UniProtKB/Swiss-Prot: April 11, 2003
Last sequence update: March 1, 2003
Last modified: January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Brucella suis

Brucella suis (strain 1330): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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