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Q8FVE4 (OCD_BRUSU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ornithine cyclodeaminase

Short name=OCD
EC=4.3.1.12
Gene names
Name:arcB
Ordered Locus Names:BRA0899, BS1330_II0891
OrganismBrucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]
Taxonomic identifier204722 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length358 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-ornithine = L-proline + NH3.

Cofactor

NAD.

Pathway

Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-ornithine: step 1/1.

Sequence similarities

Belongs to the ornithine cyclodeaminase family.

Ontologies

Keywords
   Biological processArginine metabolism
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processL-proline biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

arginine metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionornithine cyclodeaminase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 358358Ornithine cyclodeaminase
PRO_0000200672

Sequences

Sequence LengthMass (Da)Tools
Q8FVE4 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: DA2F02B1171B4C81

FASTA35839,299
        10         20         30         40         50         60 
MTQPNLNIVP FVSVDHMMKL VLRVGVETFL KELAGYVEED FRRWQNFDKT PRVASHSKEG 

        70         80         90        100        110        120 
VIELMPTSDG TLYGFKYVNG HPKNTRDGLQ TVTAFGVLAN VGSGYPMLLT EMTILTALRT 

       130        140        150        160        170        180 
AATSAVAAKH LAPKNARTMA IIGNGAQSEF QALAFKAILG VDKLRLYDLD PQATAKCIRN 

       190        200        210        220        230        240 
LQGAGFDIVA CKSVEEAVEG ADIITTVTAD KANATILTDN MVGAGVHINA VGGDCPGKTE 

       250        260        270        280        290        300 
LHGDILRRSD IFVEYPPQTR IEGEIQQLPE DYPVNELWEV ITGRIAGRKD ARQITLFDSV 

       310        320        330        340        350 
GFATEDFSAL RYVRDKLKDT GLYEQLDLLA DPDEPRDLYG MLLRHEKLLQ SESTKPAA 

« Hide

References

[1]"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts."
Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. expand/collapse author list , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M.
Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.
[2]"Revised genome sequence of Brucella suis 1330."
Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R.
J. Bacteriol. 193:6410-6410(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014292 Genomic DNA. Translation: AAN34071.1.
CP002998 Genomic DNA. Translation: AEM20347.1.
RefSeqNP_700066.1. NC_004311.2.
YP_005614573.1. NC_017250.1.

3D structure databases

ProteinModelPortalQ8FVE4.
SMRQ8FVE4. Positions 11-339.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING204722.BRA0899.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN34071; AAN34071; BRA0899.
AEM20347; AEM20347; BS1330_II0891.
GeneID1165343.
12139121.
KEGGbms:BRA0899.
bsi:BS1330_II0891.
PATRIC17794617. VBIBruSui107850_3117.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2423.
HOGENOMHOG000137262.
KOK01750.
OMAVFVEYPP.
OrthoDBEOG6C0149.

Enzyme and pathway databases

UniPathwayUPA00098; UER00357.

Family and domain databases

Gene3D3.30.1780.10. 1 hit.
3.40.50.720. 1 hit.
InterProIPR016040. NAD(P)-bd_dom.
IPR003462. ODC_Mu_crystall.
IPR023401. ODC_N.
[Graphical view]
PfamPF02423. OCD_Mu_crystall. 1 hit.
[Graphical view]
PIRSFPIRSF001439. CryM. 1 hit.
ProtoNetSearch...

Entry information

Entry nameOCD_BRUSU
AccessionPrimary (citable) accession number: Q8FVE4
Secondary accession number(s): G0KDQ9
Entry history
Integrated into UniProtKB/Swiss-Prot: November 7, 2003
Last sequence update: March 1, 2003
Last modified: May 14, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Brucella suis

Brucella suis (strain 1330): entries and gene names