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Protein

Ornithine cyclodeaminase

Gene

arcB

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-ornithine = L-proline + NH3.

Cofactori

Pathwayi

GO - Molecular functioni

  1. ornithine cyclodeaminase activity Source: UniProtKB-EC

GO - Biological processi

  1. arginine metabolic process Source: UniProtKB-KW
  2. L-proline biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Arginine metabolism

Keywords - Ligandi

NAD

Enzyme and pathway databases

UniPathwayiUPA00098; UER00357.

Names & Taxonomyi

Protein namesi
Recommended name:
Ornithine cyclodeaminase (EC:4.3.1.12)
Short name:
OCD
Gene namesi
Name:arcB
Ordered Locus Names:BRA0899, BS1330_II0891
OrganismiBrucella suis biovar 1 (strain 1330)
Taxonomic identifieri204722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000824: Chromosome II, UP000007104: Chromosome II

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 358358Ornithine cyclodeaminasePRO_0000200672Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi204722.BRA0899.

Structurei

3D structure databases

ProteinModelPortaliQ8FVE4.
SMRiQ8FVE4. Positions 11-339.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ornithine cyclodeaminase family.Curated

Phylogenomic databases

eggNOGiCOG2423.
HOGENOMiHOG000137262.
KOiK01750.
OMAiVNGHPRN.
OrthoDBiEOG6C0149.

Family and domain databases

Gene3Di3.30.1780.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR003462. ODC_Mu_crystall.
IPR023401. ODC_N.
[Graphical view]
PfamiPF02423. OCD_Mu_crystall. 1 hit.
[Graphical view]
PIRSFiPIRSF001439. CryM. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8FVE4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTQPNLNIVP FVSVDHMMKL VLRVGVETFL KELAGYVEED FRRWQNFDKT
60 70 80 90 100
PRVASHSKEG VIELMPTSDG TLYGFKYVNG HPKNTRDGLQ TVTAFGVLAN
110 120 130 140 150
VGSGYPMLLT EMTILTALRT AATSAVAAKH LAPKNARTMA IIGNGAQSEF
160 170 180 190 200
QALAFKAILG VDKLRLYDLD PQATAKCIRN LQGAGFDIVA CKSVEEAVEG
210 220 230 240 250
ADIITTVTAD KANATILTDN MVGAGVHINA VGGDCPGKTE LHGDILRRSD
260 270 280 290 300
IFVEYPPQTR IEGEIQQLPE DYPVNELWEV ITGRIAGRKD ARQITLFDSV
310 320 330 340 350
GFATEDFSAL RYVRDKLKDT GLYEQLDLLA DPDEPRDLYG MLLRHEKLLQ

SESTKPAA
Length:358
Mass (Da):39,299
Last modified:March 1, 2003 - v1
Checksum:iDA2F02B1171B4C81
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014292 Genomic DNA. Translation: AAN34071.1.
CP002998 Genomic DNA. Translation: AEM20347.1.
RefSeqiNP_700066.1. NC_004311.2.
YP_005614573.1. NC_017250.1.

Genome annotation databases

EnsemblBacteriaiAAN34071; AAN34071; BRA0899.
AEM20347; AEM20347; BS1330_II0891.
GeneIDi1165343.
12139121.
KEGGibms:BRA0899.
bsi:BS1330_II0891.
PATRICi17794617. VBIBruSui107850_3117.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014292 Genomic DNA. Translation: AAN34071.1.
CP002998 Genomic DNA. Translation: AEM20347.1.
RefSeqiNP_700066.1. NC_004311.2.
YP_005614573.1. NC_017250.1.

3D structure databases

ProteinModelPortaliQ8FVE4.
SMRiQ8FVE4. Positions 11-339.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi204722.BRA0899.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN34071; AAN34071; BRA0899.
AEM20347; AEM20347; BS1330_II0891.
GeneIDi1165343.
12139121.
KEGGibms:BRA0899.
bsi:BS1330_II0891.
PATRICi17794617. VBIBruSui107850_3117.

Phylogenomic databases

eggNOGiCOG2423.
HOGENOMiHOG000137262.
KOiK01750.
OMAiVNGHPRN.
OrthoDBiEOG6C0149.

Enzyme and pathway databases

UniPathwayiUPA00098; UER00357.

Family and domain databases

Gene3Di3.30.1780.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR003462. ODC_Mu_crystall.
IPR023401. ODC_N.
[Graphical view]
PfamiPF02423. OCD_Mu_crystall. 1 hit.
[Graphical view]
PIRSFiPIRSF001439. CryM. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.

Entry informationi

Entry nameiOCD_BRUSU
AccessioniPrimary (citable) accession number: Q8FVE4
Secondary accession number(s): G0KDQ9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 7, 2003
Last sequence update: March 1, 2003
Last modified: January 7, 2015
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella suis
    Brucella suis (strain 1330): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.