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Q8FVC0 (DADA_BRUSU) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
D-amino acid dehydrogenase small subunit

EC=1.4.99.1
Gene names
Name:dadA
Ordered Locus Names:BRA0924, BS1330_II0916
OrganismBrucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]
Taxonomic identifier204722 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length416 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Oxidative deamination of D-amino acids By similarity. HAMAP-Rule MF_01202

Catalytic activity

A D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor. HAMAP-Rule MF_01202

Cofactor

FAD By similarity. HAMAP-Rule MF_01202

Subunit structure

Heterodimer of a small and a large subunit By similarity.

Sequence similarities

Belongs to the DadA oxidoreductase family.

Ontologies

Keywords
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processD-amino acid catabolic process

Inferred from electronic annotation. Source: InterPro

alanine catabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionD-amino-acid dehydrogenase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 416416D-amino acid dehydrogenase small subunit HAMAP-Rule MF_01202
PRO_0000166129

Regions

Nucleotide binding3 – 1715FAD Potential

Sequences

Sequence LengthMass (Da)Tools
Q8FVC0 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 25CF556CD82D0CA5

FASTA41645,094
        10         20         30         40         50         60 
MQITILGSGV IGVTTAYYLA KLGHEVTVID REEGPAPETS FANAGQVSPG YASPWAAPGI 

        70         80         90        100        110        120 
PLKAAKWLFQ KHAPLILRLT TDPVQYRWLL QMLANCTDSR YKINKTRMVR VAEYSRDCLI 

       130        140        150        160        170        180 
ELRKDTGIEY DQRSQGTLQL FREQYQLDGI GKDIEVLRQD GVPFEVLDRD GCVNVEPALA 

       190        200        210        220        230        240 
HAKDKFVGGL RLPNDETGDC FKFTNALAKI AEGLGVKFRF GVNIKSLLMS GGKISGVETS 

       250        260        270        280        290        300 
EGIVTAERYV VALGSYTPAL IKALGLNAPI YPVKGYSITA PIVDESRAPV STVLDESYKI 

       310        320        330        340        350        360 
AITRLGDRIR VGGMAEVSGF TDDLPAARRA TLDLSVTDLF PGGDLKAATF WSGLRPMTPD 

       370        380        390        400        410 
STPIIGGTRY DNLFINAGHG TLGWTMACGS GRLLADLISG NKADIRADDL GIARYN 

« Hide

References

[1]"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts."
Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. expand/collapse author list , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M.
Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.
[2]"Revised genome sequence of Brucella suis 1330."
Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R.
J. Bacteriol. 193:6410-6410(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014292 Genomic DNA. Translation: AAN34096.1.
CP002998 Genomic DNA. Translation: AEM20372.1.
RefSeqNP_700091.1. NC_004311.2.
YP_005614598.1. NC_017250.1.

3D structure databases

ProteinModelPortalQ8FVC0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING204722.BRA0924.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN34096; AAN34096; BRA0924.
AEM20372; AEM20372; BS1330_II0916.
GeneID1165368.
12139147.
KEGGbms:BRA0924.
bsi:BS1330_II0916.
PATRIC17794665. VBIBruSui107850_3141.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0665.
HOGENOMHOG000217450.
KOK00285.
OMANDLYPRG.
OrthoDBEOG6KMBD9.
ProtClustDBPRK00711.

Family and domain databases

HAMAPMF_01202. DadA.
InterProIPR023080. D-aa_DH_ssu_DadA.
IPR006076. FAD-dep_OxRdtase.
[Graphical view]
PfamPF01266. DAO. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDADA_BRUSU
AccessionPrimary (citable) accession number: Q8FVC0
Secondary accession number(s): G0KDT4
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2003
Last sequence update: March 1, 2003
Last modified: February 19, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella suis

Brucella suis (strain 1330): entries and gene names