Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q8FUU5 (ZNUC_BRUSU) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 86. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Zinc import ATP-binding protein ZnuC

EC=3.6.3.-
Gene names
Name:znuC
Ordered Locus Names:BRA1123, BS1330_II1114
OrganismBrucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]
Taxonomic identifier204722 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length298 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system By similarity.

Subunit structure

The complex is composed of two ATP-binding proteins (ZnuC), two transmembrane proteins (ZnuB) and a solute-binding protein (ZnuA) Potential.

Subcellular location

Cell inner membrane; Peripheral membrane protein By similarity.

Sequence similarities

Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. [View classification]

Contains 1 ABC transporter domain.

Ontologies

Keywords
   Biological processIon transport
Transport
Zinc transport
   Cellular componentCell inner membrane
Cell membrane
Membrane
   LigandATP-binding
Nucleotide-binding
Zinc
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentplasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

ATPase activity

Inferred from electronic annotation. Source: InterPro

zinc transporting ATPase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 298298Zinc import ATP-binding protein ZnuC
PRO_0000281498

Regions

Domain17 – 232216ABC transporter
Nucleotide binding49 – 568ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q8FUU5 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 7334CC45DDBAE000

FASTA29832,247
        10         20         30         40         50         60 
MDKKSSHPAG AARDILIELR NAGVYRDGRW LVRNVDLSVE RGEIVTLIGP NGAGKSTAAK 

        70         80         90        100        110        120 
MALHILKPDE GMVSHKPGLR IGYVPQKINI DRTLPLSVER LMTLTGPLPR KEIDAALEAV 

       130        140        150        160        170        180 
GIAHLAKAET AHLSGGEFQR ALMARALARK PDIMVLDEPV QGVDFSGEAA LYELIARLRD 

       190        200        210        220        230        240 
DTGCGVLLSS HDLHLVMAAT DRVICLNGHV CCSGTPRDVT SSPEYVRLFG SRAVGPLAVY 

       250        260        270        280        290 
EHHHDHTHLP DGRVLYADGT TADPIAGSTM GPRGHCHVED GHHHDHEHHH HEGGQPRA 

« Hide

References

[1]"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts."
Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. expand/collapse author list , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M.
Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.
[2]"Revised genome sequence of Brucella suis 1330."
Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R.
J. Bacteriol. 193:6410-6410(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014292 Genomic DNA. Translation: AAN34283.1.
CP002998 Genomic DNA. Translation: AEM20559.1.
RefSeqNP_700278.1. NC_004311.2.
YP_005614785.1. NC_017250.1.

3D structure databases

ProteinModelPortalQ8FUU5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING204722.BRA1123.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN34283; AAN34283; BRA1123.
AEM20559; AEM20559; BS1330_II1114.
GeneID1165576.
12139360.
KEGGbms:BRA1123.
bsi:BS1330_II1114.
PATRIC17795105. VBIBruSui107850_3351.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1121.
KOK09817.
OMAWRKPKLR.
OrthoDBEOG6VXF80.
ProtClustDBCLSK881518.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
InterProIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR017882. ABC_transptr_Zn_ATP-bd_ZnuC.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
PS51298. ZNUC. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROQ8FUU5.

Entry information

Entry nameZNUC_BRUSU
AccessionPrimary (citable) accession number: Q8FUU5
Secondary accession number(s): G0KEC1
Entry history
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: March 1, 2003
Last modified: April 16, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella suis

Brucella suis (strain 1330): entries and gene names