Q8FUU5 (ZNUC_BRUSU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Zinc import ATP-binding protein ZnuC
EC=3.6.3.-

Gene names

Name:	znuC
Ordered Locus Names:	BRA1123, BS1330_II1114

Organism

Brucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]

Taxonomic identifier

204722 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella suis

Protein attributes

Sequence length	298 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system By similarity.
Subunit structure	The complex is composed of two ATP-binding proteins (ZnuC), two transmembrane proteins (ZnuB) and a solute-binding protein (ZnuA) Potential.
Subcellular location	Cell inner membrane; Peripheral membrane protein By similarity.
Sequence similarities	Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. [View classification] Contains 1 ABC transporter domain.

Ontologies

Keywords
Biological process	Ion transport Transport Zinc transport
Cellular component	Cell inner membrane Cell membrane Membrane
Ligand	ATP-binding Nucleotide-binding Zinc
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	ATP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity Inferred from electronic annotation. Source: InterPro zinc transporting ATPase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 298	298	Zinc import ATP-binding protein ZnuC		PRO_0000281498
Regions
	Domain	17 – 232	216	ABC transporter
	Nucleotide binding	49 – 56	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q8FUU5 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 7334CC45DDBAE000	FASTA	298	32,247
	10 20 30 40 50 60 MDKKSSHPAG AARDILIELR NAGVYRDGRW LVRNVDLSVE RGEIVTLIGP NGAGKSTAAK 70 80 90 100 110 120 MALHILKPDE GMVSHKPGLR IGYVPQKINI DRTLPLSVER LMTLTGPLPR KEIDAALEAV 130 140 150 160 170 180 GIAHLAKAET AHLSGGEFQR ALMARALARK PDIMVLDEPV QGVDFSGEAA LYELIARLRD 190 200 210 220 230 240 DTGCGVLLSS HDLHLVMAAT DRVICLNGHV CCSGTPRDVT SSPEYVRLFG SRAVGPLAVY 250 260 270 280 290 EHHHDHTHLP DGRVLYADGT TADPIAGSTM GPRGHCHVED GHHHDHEHHH HEGGQPRA

References

[1]

"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts." Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.

[2]

"Revised genome sequence of Brucella suis 1330." Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R. J. Bacteriol. 193:6410-6410(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014292 Genomic DNA. Translation: AAN34283.1. CP002998 Genomic DNA. Translation: AEM20559.1.
RefSeq	NP_700278.1. NC_004311.2. YP_005614785.1. NC_017250.1.
3D structure databases
ProteinModelPortal	Q8FUU5.
ModBase	Search...
Protein-protein interaction databases
STRING	204722.BRA1123.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAN34283; AAN34283; BRA1123. AEM20559; AEM20559; BS1330_II1114.
GeneID	1165576. 12139360.
KEGG	bms:BRA1123. bsi:BS1330_II1114.
PATRIC	17795105. VBIBruSui107850_3351.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1121.
KO	K09817.
OMA	GVRREQA.
ProtClustDB	CLSK881518.
Family and domain databases
InterPro	IPR003593. AAA+_ATPase. IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR017882. ABC_transptr_Zn_ATP-bd_ZnuC. [Graphical view]
Pfam	PF00005. ABC_tran. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
PROSITE	PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 1 hit. PS51298. ZNUC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ZNUC_BRUSU

Accession

Primary (citable) accession number: Q8FUU5
Secondary accession number(s): G0KEC1

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 20, 2007
Last sequence update:	March 1, 2003
Last modified:	May 1, 2013
This is version 81 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program