Q8FUR8 (XYLG_BRUSU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Xylose import ATP-binding protein XylG
EC=3.6.3.17

Gene names

Name:	xylG
Ordered Locus Names:	BRA1151, BS1330_II1142

Organism

Brucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]

Taxonomic identifier

204722 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella suis

Protein attributes

Sequence length	511 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system By similarity.
Catalytic activity	ATP + H2O + monosaccharide(Out) = ADP + phosphate + monosaccharide(In).
Subunit structure	The complex is composed of two ATP-binding proteins (XylG), two transmembrane proteins (XylH) and a solute-binding protein (XylF) Potential.
Subcellular location	Cell inner membrane; Peripheral membrane protein By similarity.
Sequence similarities	Belongs to the ABC transporter superfamily. Xylose importer (TC 3.A.1.2.4) family. [View classification] Contains 2 ABC transporter domains.

Ontologies

Keywords
Biological process	Sugar transport Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Repeat
Ligand	ATP-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	ATP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW D-xylose-importing ATPase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 511	511	Xylose import ATP-binding protein XylG		PRO_0000271496
Regions
	Domain	6 – 244	239	ABC transporter 1
	Domain	261 – 506	246	ABC transporter 2
	Nucleotide binding	38 – 45	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q8FUR8 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 262044FA7B92B81E	FASTA	511	55,851
	10 20 30 40 50 60 MSEYLLEMRN IGKEFNGVKA LDGIYLKVRA GECVELCGEN GAGKSTLMKV PSGVYPHGTW 70 80 90 100 110 120 TGEIFWEGKE LKASGIRDTE AAGIVIIHQE LMMVPHLSVA ENIFLGCEPT TGGFIDYDQM 130 140 150 160 170 180 NARAAELLAR LKINDINVAL PVYHYSGGKQ QLIEIAKAIN KNAKLLILDE PTSALTASET 190 200 210 220 230 240 RVLIDLIKDF KKQGMACVYI SHKLDEVAEI SDTVTVIRDG AHIATRPMSE LTTPDIITMM 250 260 270 280 290 300 VGREMKNLFP REPHDIGEVM FEARNISCWD VTNPGRKVVD DVSFALRRGE ILGIAGLVGA 310 320 330 340 350 360 GRTELVSSLF GVWPGACQGQ VFLEGKEIKI RTPRDAVRQG ICMVPEDHKR DGILPIMPVG 370 380 390 400 410 420 HNMTISVLDR FSLRGLIDKD AELVAIQREI LRLKVKTADP MLAIASLSGG NQQKAVLSKM 430 440 450 460 470 480 MLPDPKVLIL DEPTRGVDVG AKYEIYKLIF ALARQGVSIL MVSSEMPEVL GISDRVLVIG 490 500 510 EGKLRGDFPN ENLTQEKVLA AAIGKPATNA A

References

[1]

"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts." Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.

[2]

"Revised genome sequence of Brucella suis 1330." Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R. J. Bacteriol. 193:6410-6410(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014292 Genomic DNA. Translation: AAN34310.1. CP002998 Genomic DNA. Translation: AEM20586.1.
RefSeq	NP_700305.1. NC_004311.2. YP_005614812.1. NC_017250.1.
3D structure databases
ProteinModelPortal	Q8FUR8.
ModBase	Search...
Protein-protein interaction databases
STRING	204722.BRA1151.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAN34310; AAN34310; BRA1151. AEM20586; AEM20586; BS1330_II1142.
GeneID	1165604. 12139390.
KEGG	bms:BRA1151. bsi:BS1330_II1142.
PATRIC	17795167. VBIBruSui107850_3382.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1129.
KO	K10545.
OMA	LPGGRMH.
ProtClustDB	PRK13549.
Family and domain databases
InterPro	IPR003593. AAA+_ATPase. IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR013455. ABC_transptr_xylose_ATP-bd. IPR027417. P-loop_NTPase. [Graphical view]
Pfam	PF00005. ABC_tran. 2 hits. [Graphical view]
SMART	SM00382. AAA. 2 hits. [Graphical view]
SUPFAM	SSF52540. SSF52540. 2 hits.
TIGRFAMs	TIGR02633. xylG. 1 hit.
PROSITE	PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 2 hits. PS51280. XYLG. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

XYLG_BRUSU

Accession

Primary (citable) accession number: Q8FUR8
Secondary accession number(s): G0KEE8

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 9, 2007
Last sequence update:	March 1, 2003
Last modified:	May 29, 2013
This is version 83 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program