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Q8FUI5

- PKN1_COREF

UniProt

Q8FUI5 - PKN1_COREF

Protein

Probable serine/threonine-protein kinase CE0033

Gene

CE0033

Organism
Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 75 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei38 – 381ATPPROSITE-ProRule annotation
    Active sitei136 – 1361Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi15 – 239ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. penicillin binding Source: InterPro
    3. protein serine/threonine kinase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable serine/threonine-protein kinase CE0033 (EC:2.7.11.1)
    Gene namesi
    Ordered Locus Names:CE0033
    OrganismiCorynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
    Taxonomic identifieri196164 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
    ProteomesiUP000001409: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 660660Probable serine/threonine-protein kinase CE0033PRO_0000171196Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi196164.CE0033.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8FUI5.
    SMRiQ8FUI5. Positions 5-275.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini9 – 278270Protein kinasePROSITE-ProRule annotationAdd
    BLAST
    Domaini377 – 44367PASTA 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini444 – 51269PASTA 2PROSITE-ProRule annotationAdd
    BLAST
    Domaini513 – 57765PASTA 3PROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
    Contains 3 PASTA domains.PROSITE-ProRule annotation
    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    HOGENOMiHOG000037185.
    KOiK08884.
    OMAiMSKNPAN.
    OrthoDBiEOG6B35XT.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR005543. PASTA_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF03793. PASTA. 4 hits.
    PF00069. Pkinase. 1 hit.
    [Graphical view]
    SMARTiSM00740. PASTA. 3 hits.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS51178. PASTA. 4 hits.
    PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8FUI5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTFVIADRYE LGASIGSGGM SEVFAATDLL IGREVAVKML RTDLAKDVNF    50
    RERFRREAQN AGKLSHPSIV AVFDTGEVDR DGISVPYIVM ERVHGRDLRD 100
    IVREDGPYSP SQAATIMIPV CHALQSSHEA GIIHRDVKPA NIMINNTGGV 150
    KVMDFGIARA LDDSTSAMTQ TAAVIGTAQY LSPEQARGKP ADARSDVYAA 200
    GCVLYELVTG RPPFEGESPF AVAYQHVQEE PTPPSEYISD LSPTAALNVD 250
    AVVLTAMAKH PADRYQTAAE MAADLELLSR NAVSRAARAH VEKPDEPETV 300
    VVPQRLSTPP PPPTPAMPAA TVAAPAAAPT AVGSRPAAAR QPKRGSRALT 350
    VLAIVLTLGV IGVGGAFTYD FLSNSSSAST QQIPNIVGLP ENEAVLELER 400
    LGFTVVLTTE PSPDVAEGLV IRTSPNVGSE IREGATVTLT ISSGREVVTI 450
    PDVTGLTLAE ATREIEGAGL VLDQSIREEN SDDYPAGTVI QQNPRAGGET 500
    SVGASITLTV STGPSLVRVP VITGMQWSQA ESNITSLGLV PDIYYVDSLL 550
    PEGQVISASG QGTELPRGST VTVEISNGML IEAPDLARLD VDNALKALRD 600
    AGWTAPDTSL IEGAPIPTGA LVDQGRIGFQ DPSPGQPLRK DAVVNIRLYR 650
    FDLTALVPEP 660
    Length:660
    Mass (Da):69,647
    Last modified:March 1, 2003 - v1
    Checksum:iD33D797EB02D44B1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000035 Genomic DNA. Translation: BAC16843.1.
    RefSeqiNP_736643.1. NC_004369.1.
    WP_006768658.1. NZ_GG700684.1.

    Genome annotation databases

    EnsemblBacteriaiBAC16843; BAC16843; BAC16843.
    GeneIDi1032162.
    KEGGicef:CE0033.
    PATRICi21486251. VBICorEff9312_0081.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000035 Genomic DNA. Translation: BAC16843.1 .
    RefSeqi NP_736643.1. NC_004369.1.
    WP_006768658.1. NZ_GG700684.1.

    3D structure databases

    ProteinModelPortali Q8FUI5.
    SMRi Q8FUI5. Positions 5-275.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 196164.CE0033.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAC16843 ; BAC16843 ; BAC16843 .
    GeneIDi 1032162.
    KEGGi cef:CE0033.
    PATRICi 21486251. VBICorEff9312_0081.

    Phylogenomic databases

    HOGENOMi HOG000037185.
    KOi K08884.
    OMAi MSKNPAN.
    OrthoDBi EOG6B35XT.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR005543. PASTA_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF03793. PASTA. 4 hits.
    PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SMARTi SM00740. PASTA. 3 hits.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS51178. PASTA. 4 hits.
    PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Comparative complete genome sequence analysis of the amino acid replacements responsible for the thermostability of Corynebacterium efficiens."
      Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S., Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T.
      Genome Res. 13:1572-1579(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395.

    Entry informationi

    Entry nameiPKN1_COREF
    AccessioniPrimary (citable) accession number: Q8FUI5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 4, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 75 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3