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Q8FUI5

- PKN1_COREF

UniProt

Q8FUI5 - PKN1_COREF

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Protein

Probable serine/threonine-protein kinase CE0033

Gene

CE0033

Organism
Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei38 – 381ATPPROSITE-ProRule annotation
Active sitei136 – 1361Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi15 – 239ATPPROSITE-ProRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. penicillin binding Source: InterPro
  3. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable serine/threonine-protein kinase CE0033 (EC:2.7.11.1)
Gene namesi
Ordered Locus Names:CE0033
OrganismiCorynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
Taxonomic identifieri196164 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
ProteomesiUP000001409: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 660660Probable serine/threonine-protein kinase CE0033PRO_0000171196Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi196164.CE0033.

Structurei

3D structure databases

ProteinModelPortaliQ8FUI5.
SMRiQ8FUI5. Positions 5-275.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini9 – 278270Protein kinasePROSITE-ProRule annotationAdd
BLAST
Domaini377 – 44367PASTA 1PROSITE-ProRule annotationAdd
BLAST
Domaini444 – 51269PASTA 2PROSITE-ProRule annotationAdd
BLAST
Domaini513 – 57765PASTA 3PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
Contains 3 PASTA domains.PROSITE-ProRule annotation
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

HOGENOMiHOG000037185.
KOiK08884.
OMAiMSKNPAN.
OrthoDBiEOG6B35XT.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF03793. PASTA. 4 hits.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00740. PASTA. 3 hits.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS51178. PASTA. 4 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8FUI5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTFVIADRYE LGASIGSGGM SEVFAATDLL IGREVAVKML RTDLAKDVNF
60 70 80 90 100
RERFRREAQN AGKLSHPSIV AVFDTGEVDR DGISVPYIVM ERVHGRDLRD
110 120 130 140 150
IVREDGPYSP SQAATIMIPV CHALQSSHEA GIIHRDVKPA NIMINNTGGV
160 170 180 190 200
KVMDFGIARA LDDSTSAMTQ TAAVIGTAQY LSPEQARGKP ADARSDVYAA
210 220 230 240 250
GCVLYELVTG RPPFEGESPF AVAYQHVQEE PTPPSEYISD LSPTAALNVD
260 270 280 290 300
AVVLTAMAKH PADRYQTAAE MAADLELLSR NAVSRAARAH VEKPDEPETV
310 320 330 340 350
VVPQRLSTPP PPPTPAMPAA TVAAPAAAPT AVGSRPAAAR QPKRGSRALT
360 370 380 390 400
VLAIVLTLGV IGVGGAFTYD FLSNSSSAST QQIPNIVGLP ENEAVLELER
410 420 430 440 450
LGFTVVLTTE PSPDVAEGLV IRTSPNVGSE IREGATVTLT ISSGREVVTI
460 470 480 490 500
PDVTGLTLAE ATREIEGAGL VLDQSIREEN SDDYPAGTVI QQNPRAGGET
510 520 530 540 550
SVGASITLTV STGPSLVRVP VITGMQWSQA ESNITSLGLV PDIYYVDSLL
560 570 580 590 600
PEGQVISASG QGTELPRGST VTVEISNGML IEAPDLARLD VDNALKALRD
610 620 630 640 650
AGWTAPDTSL IEGAPIPTGA LVDQGRIGFQ DPSPGQPLRK DAVVNIRLYR
660
FDLTALVPEP
Length:660
Mass (Da):69,647
Last modified:March 1, 2003 - v1
Checksum:iD33D797EB02D44B1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000035 Genomic DNA. Translation: BAC16843.1.
RefSeqiNP_736643.1. NC_004369.1.
WP_006768658.1. NZ_GG700684.1.

Genome annotation databases

EnsemblBacteriaiBAC16843; BAC16843; BAC16843.
GeneIDi1032162.
KEGGicef:CE0033.
PATRICi21486251. VBICorEff9312_0081.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000035 Genomic DNA. Translation: BAC16843.1 .
RefSeqi NP_736643.1. NC_004369.1.
WP_006768658.1. NZ_GG700684.1.

3D structure databases

ProteinModelPortali Q8FUI5.
SMRi Q8FUI5. Positions 5-275.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 196164.CE0033.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAC16843 ; BAC16843 ; BAC16843 .
GeneIDi 1032162.
KEGGi cef:CE0033.
PATRICi 21486251. VBICorEff9312_0081.

Phylogenomic databases

HOGENOMi HOG000037185.
KOi K08884.
OMAi MSKNPAN.
OrthoDBi EOG6B35XT.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF03793. PASTA. 4 hits.
PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00740. PASTA. 3 hits.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS51178. PASTA. 4 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Comparative complete genome sequence analysis of the amino acid replacements responsible for the thermostability of Corynebacterium efficiens."
    Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S., Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T.
    Genome Res. 13:1572-1579(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395.

Entry informationi

Entry nameiPKN1_COREF
AccessioniPrimary (citable) accession number: Q8FUI5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2003
Last sequence update: March 1, 2003
Last modified: October 1, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3