Q8FUI5 (PKN1_COREF) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable serine/threonine-protein kinase CE0033
EC=2.7.11.1

Gene names

Ordered Locus Names:

CE0033

Organism

Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395) [Complete proteome] [HAMAP]

Taxonomic identifier

196164 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium › Corynebacterium efficiens

Protein attributes

Sequence length	660 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + a protein = ADP + a phosphoprotein.
Sequence similarities	Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Contains 3 PASTA domains. Contains 1 protein kinase domain.

Ontologies

Keywords
Domain	Repeat
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW penicillin binding Inferred from electronic annotation. Source: InterPro protein serine/threonine kinase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 660	660	Probable serine/threonine-protein kinase CE0033		PRO_0000171196
Regions
	Domain	9 – 278	270	Protein kinase
	Domain	377 – 443	67	PASTA 1
	Domain	444 – 512	69	PASTA 2
	Domain	513 – 577	65	PASTA 3
	Nucleotide binding	15 – 23	9	ATP By similarity
Sites
	Active site	136	1	Proton acceptor By similarity
	Binding site	38	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8FUI5 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: D33D797EB02D44B1	FASTA	660	69,647
	10 20 30 40 50 60 MTFVIADRYE LGASIGSGGM SEVFAATDLL IGREVAVKML RTDLAKDVNF RERFRREAQN 70 80 90 100 110 120 AGKLSHPSIV AVFDTGEVDR DGISVPYIVM ERVHGRDLRD IVREDGPYSP SQAATIMIPV 130 140 150 160 170 180 CHALQSSHEA GIIHRDVKPA NIMINNTGGV KVMDFGIARA LDDSTSAMTQ TAAVIGTAQY 190 200 210 220 230 240 LSPEQARGKP ADARSDVYAA GCVLYELVTG RPPFEGESPF AVAYQHVQEE PTPPSEYISD 250 260 270 280 290 300 LSPTAALNVD AVVLTAMAKH PADRYQTAAE MAADLELLSR NAVSRAARAH VEKPDEPETV 310 320 330 340 350 360 VVPQRLSTPP PPPTPAMPAA TVAAPAAAPT AVGSRPAAAR QPKRGSRALT VLAIVLTLGV 370 380 390 400 410 420 IGVGGAFTYD FLSNSSSAST QQIPNIVGLP ENEAVLELER LGFTVVLTTE PSPDVAEGLV 430 440 450 460 470 480 IRTSPNVGSE IREGATVTLT ISSGREVVTI PDVTGLTLAE ATREIEGAGL VLDQSIREEN 490 500 510 520 530 540 SDDYPAGTVI QQNPRAGGET SVGASITLTV STGPSLVRVP VITGMQWSQA ESNITSLGLV 550 560 570 580 590 600 PDIYYVDSLL PEGQVISASG QGTELPRGST VTVEISNGML IEAPDLARLD VDNALKALRD 610 620 630 640 650 660 AGWTAPDTSL IEGAPIPTGA LVDQGRIGFQ DPSPGQPLRK DAVVNIRLYR FDLTALVPEP

References

[1]

"Comparative complete genome sequence analysis of the amino acid replacements responsible for the thermostability of Corynebacterium efficiens." Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S., Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T. Genome Res. 13:1572-1579(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000035 Genomic DNA. Translation: BAC16843.1.
RefSeq	NP_736643.1. NC_004369.1.
3D structure databases
ProteinModelPortal	Q8FUI5.
SMR	Q8FUI5. Positions 5-275.
ModBase	Search...
Protein-protein interaction databases
STRING	196164.CE0033.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAC16843; BAC16843; BAC16843.
GeneID	1032162.
KEGG	cef:CE0033.
PATRIC	21486251. VBICorEff9312_0081.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000037185.
KO	K08884.
OMA	TGKDPGT.
ProtClustDB	CLSK632622.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR005543. PASTA. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR008271. Ser/Thr_kinase_AS. [Graphical view]
Pfam	PF03793. PASTA. 4 hits. PF00069. Pkinase. 1 hit. [Graphical view]
SMART	SM00740. PASTA. 3 hits. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS51178. PASTA. 4 hits. PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PKN1_COREF

Accession

Primary (citable) accession number: Q8FUI5

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 4, 2003
Last sequence update:	March 1, 2003
Last modified:	May 1, 2013
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program