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Protein

Serine/threonine-protein kinases drp72

Gene

CE0034

Organism
Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei49 – 491ATPPROSITE-ProRule annotation
Active sitei148 – 1481Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi26 – 349ATPPROSITE-ProRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCEFF196164:GJW8-36-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein kinases drp72 (EC:2.7.11.1)
Gene namesi
Ordered Locus Names:CE0034
OrganismiCorynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
Taxonomic identifieri196164 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
ProteomesiUP000001409: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 520520Serine/threonine-protein kinases drp72PRO_0000171198Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi196164.CE0034.

Structurei

3D structure databases

ProteinModelPortaliQ8FUI4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini20 – 281262Protein kinasePROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi372 – 492121Pro/Thr-richAdd
BLAST

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000037187.
KOiK08884.
OMAiASEHIDS.
OrthoDBiEOG6B35XT.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8FUI4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNTADDNAKQ RLQELIGPDY TLQWIVGHGG MSTVWLADDN VNDREVAVKV
60 70 80 90 100
LRPEFSDNTE FLSRFRNEAR AAENIHSEHV VTTYDYREVA DPAGHTFCFI
110 120 130 140 150
VLEYIRGESL ADMLEREGAL PEELALDVME QAAHGLSVIH RMGLVHRDIK
160 170 180 190 200
PGNMLITANG ILKITDFGIA KAAASVPLTR TGMVVGTAQY VSPEQAQGHQ
210 220 230 240 250
VTPASDVYSL GVVGYEMLSG RRPFTGDSSV SVAIAHINEA PPQMPTSVSA
260 270 280 290 300
QARELIGIAL RKDPARRFAD GNELARAVSA VRLGNRPPQP HSPAVQATAV
310 320 330 340 350
APSPSASTAM LGQVARPTTS VPASPTVLPE RQEKRGSGVG LGLLIAAVIA
360 370 380 390 400
AVIGGIIWAG ATGVFSGDSE ETTTPETITQ TVTPTETTTS EEPTLAPPPV
410 420 430 440 450
QPTRQPVPTP DETPTRLPTT TQESPTRVSP TPEETDEPGE QTTPGGQPPL
460 470 480 490 500
STLPTSLGWQ NNQGGTGNQG NPNTTGNPAN PGTPGTTGGN GTGNAGGNSP
510 520
DAADELLMSL DELMNVGGNQ
Length:520
Mass (Da):54,631
Last modified:March 1, 2003 - v1
Checksum:i84CC987FE9F902F9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000035 Genomic DNA. Translation: BAC16844.1.
RefSeqiNP_736644.1. NC_004369.1.

Genome annotation databases

EnsemblBacteriaiBAC16844; BAC16844; BAC16844.
GeneIDi1032163.
KEGGicef:CE0034.
PATRICi21486253. VBICorEff9312_0082.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000035 Genomic DNA. Translation: BAC16844.1.
RefSeqiNP_736644.1. NC_004369.1.

3D structure databases

ProteinModelPortaliQ8FUI4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi196164.CE0034.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC16844; BAC16844; BAC16844.
GeneIDi1032163.
KEGGicef:CE0034.
PATRICi21486253. VBICorEff9312_0082.

Phylogenomic databases

HOGENOMiHOG000037187.
KOiK08884.
OMAiASEHIDS.
OrthoDBiEOG6B35XT.

Enzyme and pathway databases

BioCyciCEFF196164:GJW8-36-MONOMER.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Comparative complete genome sequence analysis of the amino acid replacements responsible for the thermostability of Corynebacterium efficiens."
    Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S., Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T.
    Genome Res. 13:1572-1579(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395.

Entry informationi

Entry nameiPKN2_COREF
AccessioniPrimary (citable) accession number: Q8FUI4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2003
Last sequence update: March 1, 2003
Last modified: February 4, 2015
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.