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Q8FUI4

- PKN2_COREF

UniProt

Q8FUI4 - PKN2_COREF

Protein

Serine/threonine-protein kinases drp72

Gene

CE0034

Organism
Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 72 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei49 – 491ATPPROSITE-ProRule annotation
    Active sitei148 – 1481Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi26 – 349ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. protein serine/threonine kinase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciCEFF196164:GJW8-36-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Serine/threonine-protein kinases drp72 (EC:2.7.11.1)
    Gene namesi
    Ordered Locus Names:CE0034
    OrganismiCorynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
    Taxonomic identifieri196164 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
    ProteomesiUP000001409: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 520520Serine/threonine-protein kinases drp72PRO_0000171198Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi196164.CE0034.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8FUI4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini20 – 281262Protein kinasePROSITE-ProRule annotationAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi372 – 492121Pro/Thr-richAdd
    BLAST

    Sequence similaritiesi

    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Phylogenomic databases

    HOGENOMiHOG000037187.
    KOiK08884.
    OMAiHGGMSTV.
    OrthoDBiEOG6B35XT.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8FUI4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNTADDNAKQ RLQELIGPDY TLQWIVGHGG MSTVWLADDN VNDREVAVKV    50
    LRPEFSDNTE FLSRFRNEAR AAENIHSEHV VTTYDYREVA DPAGHTFCFI 100
    VLEYIRGESL ADMLEREGAL PEELALDVME QAAHGLSVIH RMGLVHRDIK 150
    PGNMLITANG ILKITDFGIA KAAASVPLTR TGMVVGTAQY VSPEQAQGHQ 200
    VTPASDVYSL GVVGYEMLSG RRPFTGDSSV SVAIAHINEA PPQMPTSVSA 250
    QARELIGIAL RKDPARRFAD GNELARAVSA VRLGNRPPQP HSPAVQATAV 300
    APSPSASTAM LGQVARPTTS VPASPTVLPE RQEKRGSGVG LGLLIAAVIA 350
    AVIGGIIWAG ATGVFSGDSE ETTTPETITQ TVTPTETTTS EEPTLAPPPV 400
    QPTRQPVPTP DETPTRLPTT TQESPTRVSP TPEETDEPGE QTTPGGQPPL 450
    STLPTSLGWQ NNQGGTGNQG NPNTTGNPAN PGTPGTTGGN GTGNAGGNSP 500
    DAADELLMSL DELMNVGGNQ 520
    Length:520
    Mass (Da):54,631
    Last modified:March 1, 2003 - v1
    Checksum:i84CC987FE9F902F9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000035 Genomic DNA. Translation: BAC16844.1.
    RefSeqiNP_736644.1. NC_004369.1.
    WP_011074779.1. NC_004369.1.

    Genome annotation databases

    EnsemblBacteriaiBAC16844; BAC16844; BAC16844.
    GeneIDi1032163.
    KEGGicef:CE0034.
    PATRICi21486253. VBICorEff9312_0082.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000035 Genomic DNA. Translation: BAC16844.1 .
    RefSeqi NP_736644.1. NC_004369.1.
    WP_011074779.1. NC_004369.1.

    3D structure databases

    ProteinModelPortali Q8FUI4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 196164.CE0034.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAC16844 ; BAC16844 ; BAC16844 .
    GeneIDi 1032163.
    KEGGi cef:CE0034.
    PATRICi 21486253. VBICorEff9312_0082.

    Phylogenomic databases

    HOGENOMi HOG000037187.
    KOi K08884.
    OMAi HGGMSTV.
    OrthoDBi EOG6B35XT.

    Enzyme and pathway databases

    BioCyci CEFF196164:GJW8-36-MONOMER.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Comparative complete genome sequence analysis of the amino acid replacements responsible for the thermostability of Corynebacterium efficiens."
      Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S., Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T.
      Genome Res. 13:1572-1579(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395.

    Entry informationi

    Entry nameiPKN2_COREF
    AccessioniPrimary (citable) accession number: Q8FUI4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 4, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 72 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3