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Q8FT74 (Q8FT74_COREF) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length514 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone By similarity. HAMAP-Rule MF_00966

Catalytic activity

D-glucose 6-phosphate + NADP+ = 6-phospho-D-glucono-1,5-lactone + NADPH. RuleBase RU000497 HAMAP-Rule MF_00966

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3. RuleBase RU000497 HAMAP-Rule MF_00966

Sequence similarities

Belongs to the glucose-6-phosphate dehydrogenase family. RuleBase RU000497 HAMAP-Rule MF_00966

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2681Proton acceptor By similarity HAMAP-Rule MF_00966
Binding site691NADP By similarity HAMAP-Rule MF_00966
Binding site1761NADP By similarity HAMAP-Rule MF_00966
Binding site2061Substrate By similarity HAMAP-Rule MF_00966
Binding site2101Substrate By similarity HAMAP-Rule MF_00966
Binding site2441Substrate By similarity HAMAP-Rule MF_00966
Binding site2631Substrate By similarity HAMAP-Rule MF_00966
Binding site3661Substrate By similarity HAMAP-Rule MF_00966

Sequences

Sequence LengthMass (Da)Tools
Q8FT74 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 27CFBFDD591C42B8

FASTA51457,621
        10         20         30         40         50         60 
MSSHTNPTTW INPLRDPQDK RLPRIAGPSG LVIFGVTGDL ARKKLLPAIY DLANRGLLPP 

        70         80         90        100        110        120 
GFALVGYGRR DWSKEDFENY VREAVEAGAR TEFRGNVWER LAEGMEFVKG NFDDDSAFDN 

       130        140        150        160        170        180 
LADTLKRLDE TRGTAGNWAF YLSIPPDSFA AVCHQLERSG MAASTDESWR RVIIEKPFGN 

       190        200        210        220        230        240 
DLKTAHELNE TVNAVFPEES VFRIDHYLGK ETVQNILALR FANQLFEPLW NSNYVDHVQI 

       250        260        270        280        290        300 
TMAEDIGLGG RAGYYDGIGA ARDVIQNHLI QLLALVAMEE PISFTPTQLQ AEKIKVLRAT 

       310        320        330        340        350        360 
KPSLPIAENS ARGQYSAGWQ GSEYVKGLRE EDGFDPESTT ETYAACTLEI TSRRWAGVPF 

       370        380        390        400        410        420 
YLRTGKRLGR RVTEIAVVFK DAPHQPFDPG MTAALGNNAI VIRVQPDEGV LIRFGSKVPG 

       430        440        450        460        470        480 
SAMEVRDVNM DFSYSESFTE ESPEAYERLI LDALLDESSL FPTNEEVELS WKILDPILEI 

       490        500        510 
WEENGQPEEY PAGTWGPKSA DEMLARNGHQ WRRP 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000035 Genomic DNA. Translation: BAC18506.1.
ACLI01000086 Genomic DNA. Translation: EEW49669.1.
RefSeqNP_738306.1. NC_004369.1.

3D structure databases

ProteinModelPortalQ8FT74.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING196164.CE1696.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAC18506; BAC18506; BAC18506.
EEW49669; EEW49669; HMPREF0290_1731.
GeneID1034193.
KEGGcef:CE1696.
PATRIC21489533. VBICorEff9312_1687.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0364.
HOGENOMHOG000046191.
KOK00036.
OMAHAFTESS.
OrthoDBEOG61308Z.

Enzyme and pathway databases

UniPathwayUPA00115; UER00408.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
HAMAPMF_00966. G6PD.
InterProIPR001282. G6P_DH.
IPR019796. G6P_DH_AS.
IPR022675. G6P_DH_C.
IPR022674. G6P_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERPTHR23429. PTHR23429. 1 hit.
PfamPF02781. G6PD_C. 1 hit.
PF00479. G6PD_N. 1 hit.
[Graphical view]
PIRSFPIRSF000110. G6PD. 1 hit.
PRINTSPR00079. G6PDHDRGNASE.
TIGRFAMsTIGR00871. zwf. 1 hit.
PROSITEPS00069. G6P_DEHYDROGENASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ8FT74_COREF
AccessionPrimary (citable) accession number: Q8FT74
Secondary accession number(s): C8NP06
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: June 11, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)