Q8FT74 (Q8FT74_COREF) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Glucose-6-phosphate 1-dehydrogenase RuleBase RU000497
EC=1.1.1.49 RuleBase RU000497

Gene names

Name:	zwf EMBL EEW49669.1
ORF Names:	HMPREF0290_1731 EMBL EEW49669.1

Organism

Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395) [Complete proteome] [HAMAP] EMBL BAC18506.1

Taxonomic identifier

196164 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium › Corynebacterium efficiens

Protein attributes

Sequence length	514 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH. RuleBase RU000497
Pathway	Carbohydrate degradation; pentose phosphate pathway. RuleBase RU000497
Sequence similarities	Belongs to the glucose-6-phosphate dehydrogenase family. RuleBase RU000497

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glucose metabolism RuleBase RU000497
Ligand	NADP RuleBase RU000497
Molecular function	Oxidoreductase RuleBase RU000497 EMBL EEW49669.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	pentose-phosphate shunt Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	NADP binding Inferred from electronic annotation. Source: InterPro glucose-6-phosphate dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8FT74 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 27CFBFDD591C42B8	FASTA	514	57,621
	10 20 30 40 50 60 MSSHTNPTTW INPLRDPQDK RLPRIAGPSG LVIFGVTGDL ARKKLLPAIY DLANRGLLPP 70 80 90 100 110 120 GFALVGYGRR DWSKEDFENY VREAVEAGAR TEFRGNVWER LAEGMEFVKG NFDDDSAFDN 130 140 150 160 170 180 LADTLKRLDE TRGTAGNWAF YLSIPPDSFA AVCHQLERSG MAASTDESWR RVIIEKPFGN 190 200 210 220 230 240 DLKTAHELNE TVNAVFPEES VFRIDHYLGK ETVQNILALR FANQLFEPLW NSNYVDHVQI 250 260 270 280 290 300 TMAEDIGLGG RAGYYDGIGA ARDVIQNHLI QLLALVAMEE PISFTPTQLQ AEKIKVLRAT 310 320 330 340 350 360 KPSLPIAENS ARGQYSAGWQ GSEYVKGLRE EDGFDPESTT ETYAACTLEI TSRRWAGVPF 370 380 390 400 410 420 YLRTGKRLGR RVTEIAVVFK DAPHQPFDPG MTAALGNNAI VIRVQPDEGV LIRFGSKVPG 430 440 450 460 470 480 SAMEVRDVNM DFSYSESFTE ESPEAYERLI LDALLDESSL FPTNEEVELS WKILDPILEI 490 500 510 WEENGQPEEY PAGTWGPKSA DEMLARNGHQ WRRP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Comparative complete genome sequence analysis of the amino acid replacements responsible for the thermostability of Corynebacterium efficiens." Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S., Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T. Genome Res. 13:1572-1579(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395 and YS-314 EMBL BAC18506.1.
[2]	Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L., Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V., Kovar C., Mata R., Mathew T., Ngo R. , Nguyen L., Nguyen N., Okwuonu G., Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A., Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C., Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S., Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S., Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L., Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P., Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K., Petrosino J., Highlander S., Gibbs R. Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: YS-314 EMBL EEW49669.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000035 Genomic DNA. Translation: BAC18506.1. ACLI01000086 Genomic DNA. Translation: EEW49669.1.
RefSeq	NP_738306.1. NC_004369.1.
3D structure databases
HSSP	HSSP built from PDB template 1QKI based on UniProtKB P11413.
ModBase	Search...
Protein-protein interaction databases
STRING	196164.CE1696.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAC18506; BAC18506; BAC18506.
GeneID	1034193.
KEGG	cef:CE1696.
PATRIC	21489533. VBICorEff9312_1687.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0364.
HOGENOM	HOG000046191.
KO	K00036.
OMA	FANQMFE.
ProtClustDB	PRK05722.
Enzyme and pathway databases
BioCyc	CEFF196164:GJW8-1725-MONOMER.
UniPathway	UPA00115.
Family and domain databases
Gene3D	3.40.50.720. 1 hit.
InterPro	IPR001282. G6P_DH. IPR019796. G6P_DH_AS. IPR022675. G6P_DH_C. IPR022674. G6P_DH_NAD-bd. IPR016040. NAD(P)-bd_dom. [Graphical view]
PANTHER	PTHR23429. PTHR23429. 1 hit.
Pfam	PF02781. G6PD_C. 1 hit. PF00479. G6PD_N. 1 hit. [Graphical view]
PIRSF	PIRSF000110. G6PD. 1 hit.
PRINTS	PR00079. G6PDHDRGNASE.
TIGRFAMs	TIGR00871. zwf. 1 hit.
PROSITE	PS00069. G6P_DEHYDROGENASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8FT74_COREF

Accession

Primary (citable) accession number: Q8FT74
Secondary accession number(s): C8NP06

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	May 1, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)