Reviewed, UniProtKB/Swiss-Prot Q8FSJ0 (DEOC_COREF)

Names and origin

Protein names

Recommended name:
    Deoxyribose-phosphate aldolase
    EC=4.1.2.4
Alternative name(s):
    Phosphodeoxyriboaldolase
      Short name=Deoxyriboaldolase
      Short name=DERA

Gene names

Name:	deoC
Ordered Locus Names:	CE0401

Organism

Corynebacterium efficiens [Complete proteome] [HAMAP]

Taxonomic identifier

152794 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	222 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00114
Pathway	Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose 1-phosphate: step 2/2. HAMAP MF_00114
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Schiff base
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate catabolic process Inferred from electronic annotation. Source: HAMAP deoxyribonucleotide catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	deoxyribose-phosphate aldolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 222	222	Deoxyribose-phosphate aldolase HAMAP MF_00114		PRO_0000057229
Sites
	Active site	156	1	Schiff-base intermediate with acetaldehyde By similarity
	Active site	186	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8FSJ0-1 [UniParc]. Last modified April 26, 2004. Version 2. Checksum: E56DB37B09819089	FASTA	222	22,539
	10 20 30 40 50 60 MTITRAEMAS ILDYTLLGPE VTTADLQALI DDALTLGVPT ICIPPSMMNA TKRAQDAGLR 70 80 90 100 110 120 IATVAGFPHG KSAPLVKAAE ARLAVQYGAS EVDVVLDIAA VKAADDNALL AEMVAIREAL 130 140 150 160 170 180 ASPVTLKFIV ESAVVDDVAL EVATHAARAA GADFIKTSTG FHPAGGATVE AVRVLAGAAQ 190 200 210 220 GQIGVKASGG IRTWEQAVAM VEAGATRIGT SNARAILEGA PA

References

[1]

"Comparative complete genome sequence analysis of the amino acid replacements responsible for the thermostability of Corynebacterium efficiens." Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S., Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T. Genome Res. 13:1572-1579(2003) [PubMed: 12840036] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000035 Genomic DNA. Translation: BAC17211.1. Different initiation.
RefSeq	NP_737011.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1032522.
GenomeReviews	Gene locus CE0401 in contig BA000035_GR.
KEGG	cef:CE0401.
NMPDR	fig|196164.1.peg.401.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8FSJ0.
Enzyme and pathway databases
BioCyc	CEFF196164:CE0401-MON.
BRENDA	4.1.2.4. 277326.
Family and domain databases
HAMAP	MF_00114. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/AroFGH_arch. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
PANTHER	PTHR10889. DeoC. 1 hit.
Pfam	PF01791. DeoC. 1 hit. [Graphical view]
PIRSF	PIRSF001357. DeoC. 1 hit.
TIGRFAMs	TIGR00126. deoC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DEOC_COREF

Accession

Primary (citable) accession number: Q8FSJ0

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 26, 2004
Last sequence update:	April 26, 2004
Last modified:	June 16, 2009
This is version 42 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)