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Q8FSG3 (Q8FSG3_COREF) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Pyrroline-5-carboxylate reductase RuleBase RU003903
EC=1.5.1.2 RuleBase RU003903
Gene names
Name:proC EMBL BAC17240.1
Ordered Locus Names:CE0430
OrganismCorynebacterium efficiens [Complete proteome] [HAMAP]
Taxonomic identifier152794 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length273 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-proline + NAD(P)+ = 1-pyrroline-5-carboxylate + NAD(P)H. RuleBase RU003903

Pathway

Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1. RuleBase RU003903

Sequence similarities

Belongs to the pyrroline-5-carboxylate reductase family. RuleBase RU003903

Sequences

Sequence LengthMass (Da)Tools
Q8FSG3 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 3AA0743B15706F73

FASTA27328,424
        10         20         30         40         50         60 
MEGMTIIAVI GGGQIGEALV SGLVAADVNP QNIRVTNRRE ERGAELEERY GVVTMTDNAQ 

        70         80         90        100        110        120 
AVDGADVVFL CVKPKMILDV LAEIATTVDN NSVSTVVVSM AAGINLASME EKVSAGMPIV 

       130        140        150        160        170        180 
RVMPNTPMLV RKGMCTVTGG RFVDAEQLEL VQELLTSVGD VMVVEESDLD AVTALSGSSP 

       190        200        210        220        230        240 
AYLFLVTEAL IDAGVSLGLT RAAAKQLAVS AFDGAGTMLK ETGREPSDLR AGVSSPAGTT 

       250        260        270 
VAALRELEES GIRGAFFRAA QACADRSAEM GRN

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References

[1]"Comparative complete genome sequence analysis of the amino acid replacements responsible for the thermostability of Corynebacterium efficiens."
Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S., Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T.
Genome Res. 13:1572-1579(2003) [PubMed: 12840036] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000035 Genomic DNA. Translation: BAC17240.1.
RefSeqNP_737040.1. NC_004369.1.

3D structure databases

ProteinModelPortalQ8FSG3.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1034896.
GenomeReviewsGene locus CE0430 in contig BA000035_GR.
KEGGcef:CE0430.
NMPDRfig|196164.1.peg.430.
PATRIC21487016. VBICorEff9312_0454.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG726602.
OMARTFNEHQ.
PhylomeDBQ8FSG3.
ProtClustDBPRK11880.

Family and domain databases

InterProIPR008927. 6-PGluconate_DH_C-like.
IPR016040. NAD(P)-bd_dom.
IPR004455. NADP_OxRdtase_F420.
IPR000304. Pyrroline-COOH_reductase.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK00286.
PANTHERPTHR11645. P5CR. 1 hit.
PfamPF03807. F420_oxidored. 1 hit.
[Graphical view]
PIRSFPIRSF000193. Pyrrol-5-carb_rd. 1 hit.
SUPFAMSSF48179. 6DGDH_C_like. 1 hit.
TIGRFAMsTIGR00112. ProC. 1 hit.
PROSITEPS00521. P5CR. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ8FSG3_COREF
AccessionPrimary (citable) accession number: Q8FSG3
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: December 14, 2011
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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