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Q8FS36 (IF1_COREF) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Translation initiation factor IF-1
Gene names
Name:infA
Ordered Locus Names:CE0568
OrganismCorynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395) [Complete proteome] [HAMAP]
Taxonomic identifier196164 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium

Protein attributes

Sequence length72 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 By similarity. HAMAP-Rule MF_00075

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00075.

Sequence similarities

Belongs to the IF-1 family.

Contains 1 S1-like domain.

Sequence caution

The sequence BAC17378.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   Molecular functionInitiation factor
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functiontranslation initiation factor activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 7272Translation initiation factor IF-1 HAMAP-Rule MF_00075
PRO_0000095778

Regions

Domain1 – 7272S1-like

Sequences

Sequence LengthMass (Da)Tools
Q8FS36 [UniParc].

Last modified March 28, 2003. Version 2.
Checksum: 31A498C8150EABE9

FASTA728,361
        10         20         30         40         50         60 
MAKEGAIEVE GRVVEPLPNA MFRVELDNGH KVLAHISGKM RQHYIRILPE DRVVVELSPY 

        70 
DLTRGRIVYR YK 

« Hide

References

[1]"Comparative complete genome sequence analysis of the amino acid replacements responsible for the thermostability of Corynebacterium efficiens."
Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S., Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T.
Genome Res. 13:1572-1579(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000035 Genomic DNA. Translation: BAC17378.1. Different initiation.
RefSeqNP_737178.2. NC_004369.1.

3D structure databases

ProteinModelPortalQ8FS36.
SMRQ8FS36. Positions 2-72.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING196164.CE0568.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAC17378; BAC17378; BAC17378.
GeneID1032689.
KEGGcef:CE0568.
PATRIC21487306. VBICorEff9312_0595.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000221323.
KOK02518.
OrthoDBEOG6384SC.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
HAMAPMF_00075. IF_1.
InterProIPR012340. NA-bd_OB-fold.
IPR022967. RNA-binding_domain_S1.
IPR006196. RNA-binding_domain_S1_IF1.
IPR004368. TIF_IF1.
[Graphical view]
PfamPF01176. eIF-1a. 1 hit.
[Graphical view]
SMARTSM00316. S1. 1 hit.
[Graphical view]
SUPFAMSSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00008. infA. 1 hit.
PROSITEPS50832. S1_IF1_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameIF1_COREF
AccessionPrimary (citable) accession number: Q8FS36
Entry history
Integrated into UniProtKB/Swiss-Prot: March 28, 2003
Last sequence update: March 28, 2003
Last modified: May 14, 2014
This is version 66 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Translation initiation factors

List of translation initiation factor entries