Q8FS36 (IF1_COREF) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Translation initiation factor IF-1

Gene names

Name:	infA
Ordered Locus Names:	CE0568

Organism

Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395) [Complete proteome] [HAMAP]

Taxonomic identifier

196164 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium › Corynebacterium efficiens

Protein attributes

Sequence length	72 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 By similarity. HAMAP-Rule MF_00075
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the IF-1 family. Contains 1 S1-like domain.
Sequence caution	The sequence BAC17378.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Molecular function	Initiation factor
Technical term	Complete proteome
Gene Ontology (GO)
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	translation initiation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 72	72	Translation initiation factor IF-1 HAMAP-Rule MF_00075		PRO_0000095778
Regions
	Domain	1 – 72	72	S1-like

Sequences

	Sequence		Length	Mass (Da)
	Q8FS36 [UniParc]. Last modified March 28, 2003. Version 2. Checksum: 31A498C8150EABE9	FASTA	72	8,361
	10 20 30 40 50 60 MAKEGAIEVE GRVVEPLPNA MFRVELDNGH KVLAHISGKM RQHYIRILPE DRVVVELSPY 70 DLTRGRIVYR YK

References

[1]

"Comparative complete genome sequence analysis of the amino acid replacements responsible for the thermostability of Corynebacterium efficiens." Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S., Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T. Genome Res. 13:1572-1579(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000035 Genomic DNA. Translation: BAC17378.1. Different initiation.
RefSeq	NP_737178.2. NC_004369.1.
3D structure databases
ProteinModelPortal	Q8FS36.
SMR	Q8FS36. Positions 2-72.
ModBase	Search...
Protein-protein interaction databases
STRING	196164.CE0568.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAC17378; BAC17378; BAC17378.
GeneID	1032689.
KEGG	cef:CE0568.
PATRIC	21487306. VBICorEff9312_0595.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000221323.
KO	K02518.
ProtClustDB	PRK00276.
Family and domain databases
Gene3D	2.40.50.140. 1 hit.
HAMAP	MF_00075. IF-1.
InterPro	IPR012340. NA-bd_OB-fold. IPR022967. RNA-binding_domain_S1. IPR006196. RNA-binding_domain_S1_IF1. IPR004368. TIF_IF1. [Graphical view]
Pfam	PF01176. eIF-1a. 1 hit. [Graphical view]
SMART	SM00316. S1. 1 hit. [Graphical view]
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit.
TIGRFAMs	TIGR00008. infA. 1 hit.
PROSITE	PS50832. S1_IF1_TYPE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

IF1_COREF

Accession

Primary (citable) accession number: Q8FS36

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 28, 2003
Last sequence update:	March 28, 2003
Last modified:	May 1, 2013
This is version 61 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program