Q8FS07 (GCP_COREF) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	CE0599

Organism

Corynebacterium efficiens [Complete proteome] [HAMAP]

Taxonomic identifier

152794 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	344 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 344	344	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303337

Sequences

	Sequence		Length	Mass (Da)
	Q8FS07 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 8330D2A800DE8A8F	FASTA	344	35,509
	10 20 30 40 50 60 MIVLGIESSC DETGVGVVDL DEQGNLTILA DAVASSMQDH ARFGGVVPEI ASRAHLESMV 70 80 90 100 110 120 PVMREALHRA GIDKPDAVAA TVGPGLAGAL LVGASAAKAY AAAWDVPFYA VNHLGGHVAV 130 140 150 160 170 180 ANLDGEPLPH SVALLVSGGH TQLLEVEAVG LPMKELGSTL DDAAGEAYDK VSRLLGLGYP 190 200 210 220 230 240 GGPVIDKLAR RGDPQAIAFP RGLMKKSDSR HDFSFSGLKT AVARYVEAAE RAGEVISVED 250 260 270 280 290 300 VCASFQEAVC DVLTFKAVRA CQDVGAKVLL LGGGVAANSR LRELAQERCD AAGIELRVPS 310 320 330 340 FKLCTDNGVM IAALAAQRIH EGAGGSALTV GTDPSLAVET PQVF

References

[1]

"Comparative complete genome sequence analysis of the amino acid replacements responsible for the thermostability of Corynebacterium efficiens." Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S., Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T. Genome Res. 13:1572-1579(2003) [PubMed: 12840036] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000035 Genomic DNA. Translation: BAC17409.1.
RefSeq	NP_737209.1. NC_004369.1.
3D structure databases
ProteinModelPortal	Q8FS07.
ModBase	Search...
Protein family/group databases
MEROPS	M22.A01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1032719.
GenomeReviews	Gene locus CE0599 in contig BA000035_GR.
KEGG	cef:CE0599.
NMPDR	fig|196164.1.peg.599.
PATRIC	21487368. VBICorEff9312_0626.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG304663.
OMA	PLYGVNH.
PhylomeDB	Q8FS07.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	CEFF196164:CE0599-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_COREF

Accession

Primary (citable) accession number: Q8FS07

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	March 1, 2003
Last modified:	January 25, 2012
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program