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Protein

HTH-type transcriptional regulator RipA

Gene

ripA

Organism
Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Under iron limitation, represses the acn (aconitase), catA (catechol 1,2 dioxygenase), leuCD (isopropylmalate dehydratase), narKGHJI (nitrite/nitrate transporter and nitrate reductase), sdhCAB (succinate dehydrogenase), pta (phosphotransacetylase) and katA (catalase) genes.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi113 – 159H-T-H motifPROSITE-ProRule annotationAdd BLAST47
DNA bindingi165 – 208H-T-H motifPROSITE-ProRule annotationAdd BLAST44

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional regulator RipABy similarity
Alternative name(s):
Repressor of iron proteins ABy similarity
Short name:
RIPABy similarity
Gene namesi
Name:ripABy similarity
Ordered Locus Names:CE1047
OrganismiCorynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
Taxonomic identifieri196164 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesCorynebacteriaceaeCorynebacterium
Proteomesi
  • UP000001409 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002232381 – 332HTH-type transcriptional regulator RipAAdd BLAST332

Expressioni

Inductioni

Repressed by DtxR under iron excess.By similarity

Interactioni

Protein-protein interaction databases

STRINGi196164.HMPREF0290_1415.

Structurei

3D structure databases

ProteinModelPortaliQ8FQS2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 HTH araC/xylS-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG2207. LUCA.
HOGENOMiHOG000263853.
OrthoDBiPOG091H09TX.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
2.60.120.10. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR018062. HTH_AraC-typ_CS.
IPR014710. RmlC-like_jellyroll.
[Graphical view]
PfamiPF12833. HTH_18. 1 hit.
[Graphical view]
SMARTiSM00342. HTH_ARAC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
PROSITEiPS00041. HTH_ARAC_FAMILY_1. 1 hit.
PS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8FQS2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNARLLWCH SGVVNVCLGE QTFTLVAGDL LYAPEGAFWS DTGSGLILEL
60 70 80 90 100
RFRILGIDGP ARRIHLGRAW AERMVHEYSR SLFGEDAVSG DVAKLFADRV
110 120 130 140 150
PTPPLPAPRH ARAVAQTLAA NPADQTSLEE FAAQRGVSAR TLQRQFLSST
160 170 180 190 200
GYSFSEWRAA QRVCVATSLL AHDFSIAVVA NLVGFSATSS LTRAFRRHIG
210 220 230 240 250
TTPSAFTTGG IGMGVAGTPA AIPSRTTFAA ATRDQQLWIY TGTATVTTPG
260 270 280 290 300
YCRFLTQGDM ATIPAGTHTR IDVAAGSIAI PVPIGVGEQG MSLQEVATLR
310 320 330
DQEPSTGLML VEESRWVHLG RELLPATAPV SL
Length:332
Mass (Da):35,447
Last modified:February 7, 2006 - v2
Checksum:i2A52BC6B7EB12743
GO

Sequence cautioni

The sequence BAC17857 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000035 Genomic DNA. Translation: BAC17857.1. Different initiation.
RefSeqiWP_006769994.1. NZ_GG700688.1.

Genome annotation databases

EnsemblBacteriaiBAC17857; BAC17857; BAC17857.
KEGGicef:CE1047.
PATRICi21488230. VBICorEff9312_1049.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000035 Genomic DNA. Translation: BAC17857.1. Different initiation.
RefSeqiWP_006769994.1. NZ_GG700688.1.

3D structure databases

ProteinModelPortaliQ8FQS2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi196164.HMPREF0290_1415.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC17857; BAC17857; BAC17857.
KEGGicef:CE1047.
PATRICi21488230. VBICorEff9312_1049.

Phylogenomic databases

eggNOGiCOG2207. LUCA.
HOGENOMiHOG000263853.
OrthoDBiPOG091H09TX.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
2.60.120.10. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR018062. HTH_AraC-typ_CS.
IPR014710. RmlC-like_jellyroll.
[Graphical view]
PfamiPF12833. HTH_18. 1 hit.
[Graphical view]
SMARTiSM00342. HTH_ARAC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
PROSITEiPS00041. HTH_ARAC_FAMILY_1. 1 hit.
PS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRIPA_COREF
AccessioniPrimary (citable) accession number: Q8FQS2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 7, 2006
Last sequence update: February 7, 2006
Last modified: November 30, 2016
This is version 87 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.