Reviewed, UniProtKB/Swiss-Prot Q8FP91 (MQO_COREF)

Names and origin

Protein names

Recommended name:
    Probable malate:quinone oxidoreductase
    EC=1.1.99.16
Alternative name(s):
    Malate dehydrogenase [acceptor]
    MQO

Gene names

Name:	mqo
Ordered Locus Names:	CE1894

Organism

Corynebacterium efficiens [Complete proteome] [HAMAP]

Taxonomic identifier

152794 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	642 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(S)-malate + acceptor = oxaloacetate + reduced acceptor. HAMAP MF_00212
Cofactor	FAD By similarity.
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle. HAMAP MF_00212
Sequence similarities	In the C-terminal section; belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW tricarboxylic acid cycle Inferred from electronic annotation. Source: HAMAP
Molecular function	malate dehydrogenase (acceptor) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 642	642	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_0000128710
Regions
	Region	1 – 142	142	Unknown HAMAP MF_00212
	Region	143 – 642	500	MQO domain HAMAP MF_00212

Sequences

	Sequence		Length	Mass (Da)
	Q8FP91-1 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 19E8271DEF472725	FASTA	642	70,126
	10 20 30 40 50 60 MIVVFRHEST IGHVFLTGGD YHSGAGGFSR APSTAVTYVA PWLRTSQFPG GDRGLSGGGQ 70 80 90 100 110 120 RGRLWAYGPG YVEGIYVPPY QQAYTTELRT TCTCTPSRSR PGQVFTTCRS AIHPCAGPRV 130 140 150 160 170 180 DSCVQHAGCV RQTTRGDKRK LNMSDSPKNA QKVTDEADVV LVGAGIMSAT LGAMLRQLEP 190 200 210 220 230 240 SWSQVIFERL DGAAQESSSP WNNAGTGHSA LCELNYTPEK NGKIDISKAV NINEKFQVSR 250 260 270 280 290 300 QFWAHQVEEG ILPDPKEFIN AVPHVSFGHG ADQVAYIKNR YNALKDHPLF PGMQYADDEE 310 320 330 340 350 360 TFTEKLPLMA QGRDFSDPVA ISWIQEGTDI NYGSQSKQFL KAAEAGGTEI RYGHEVKDIT 370 380 390 400 410 420 KDGAKWKVTV KNVHTGDTQT IRANFVFVGA GGMALPLLQK SGIAEIRGFG GFPVSGQWLR 430 440 450 460 470 480 CTNEELIEQH AAKVYGKASV GAPPMSVPHL DTRVIDGEKG LLFGPYAGWT PKFLKEGSNL 490 500 510 520 530 540 DLFSSLRPTN LASLLGVGVQ EMGLTKYLIT EVVKDMEARM ESLREYMPNA KKSDWELITA 550 560 570 580 590 600 GQRVQVIKPV GAPRFGSLEF GTTLISNSEG TIAGLLGASP GASIAPAAMI ELLERCFGKR 610 620 630 640 MIEWGDKIQE MVPSYGKKLA DEPEMFAELW EYTQKTLKLE KA

References

[1]

"Comparative complete genome sequence analysis of the amino acid replacements responsible for the thermostability of Corynebacterium efficiens." Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S., Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T. Genome Res. 13:1572-1579(2003) [PubMed: 12840036] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000035 Genomic DNA. Translation: BAC18704.1.
RefSeq	NP_738504.2.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1032048.
GenomeReviews	Gene locus CE1894 in contig BA000035_GR.
KEGG	cef:CE1894.
NMPDR	fig|196164.1.peg.1894.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8FP91.
OMA	Q8FP91. HLAKAYG.
Enzyme and pathway databases
BioCyc	CEFF196164:CE1894-MON.
BRENDA	1.1.99.16. 277326.
Family and domain databases
HAMAP	MF_00212. Fused. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_COREF

Accession

Primary (citable) accession number: Q8FP91

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 2003
Last sequence update:	March 1, 2003
Last modified:	June 16, 2009
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)