Q8FP84 (Q8FP84_COREF) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Methionine aminopeptidase RuleBase RU003653
EC=3.4.11.18 RuleBase RU003653

Gene names

Ordered Locus Names:

CE1901

Organism

Corynebacterium efficiens [Complete proteome] [HAMAP]

Taxonomic identifier

152794 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	325 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Removes the N-terminal methionine from nascent proteins By similarity. RuleBase RU003653
Catalytic activity	Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides. RuleBase RU003653
Cofactor	Binds 2 cobalt ions per subunit By similarity. RuleBase RU003653
Sequence similarities	Belongs to the peptidase M24A family. RuleBase RU003653

Ontologies

Keywords
Ligand	Cobalt RuleBase RU003653 Metal-binding RuleBase RU003653
Molecular function	Aminopeptidase RuleBase RU003653 EMBL BAC18711.1 Hydrolase Protease
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular process Inferred from electronic annotation. Source: InterPro proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	aminopeptidase activity Inferred from electronic annotation. Source: UniProtKB-KW metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW metalloexopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8FP84 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: D1FA34C4771006AD	FASTA	325	35,982
	10 20 30 40 50 60 MMPRGGARRK ALPVPDSPTA PVRLPRGRGT SMVTMSTLRA PLVPGEPTPI RKVPAHIERP 70 80 90 100 110 120 EYVWKDEVLE AIGEPYVQTP EVIEAMRKTS RIAANALKVA GAAVAPGVTT DEIDRIAHEY 130 140 150 160 170 180 MCDHGAYPSD LGYRGFTKSV CVSLNEIVCH GIPDTTVIQD GDIVNIDVTA YKHGVHGDCN 190 200 210 220 230 240 ATFLSGNVSE EHRLLVERTE EALMRSIRAA KPGREINIIG RVIESYAKRF GYNVVRDFTG 250 260 270 280 290 300 HGIGPTFHNG LIVLHYDSTQ YRDLLVPGMT LTIEPMINLG SLDYEIWDDG WTVQNKDRKF 310 320 TAQFEHTIVI TEDGNEILTL PDENI

References

[1]

"Comparative complete genome sequence analysis of the amino acid replacements responsible for the thermostability of Corynebacterium efficiens." Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S., Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T. Genome Res. 13:1572-1579(2003) [PubMed: 12840036] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000035 Genomic DNA. Translation: BAC18711.1.
RefSeq	NP_738511.2. NC_004369.1.
3D structure databases
HSSP	HSSP built from PDB template 1C24 based on UniProtKB P07906.
ProteinModelPortal	Q8FP84.
SMR	Q8FP84. Positions 39-319.
ModBase	Search...
Protein family/group databases
MEROPS	M24.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1034599.
GenomeReviews	Gene locus CE1901 in contig BA000035_GR.
KEGG	cef:CE1901.
NMPDR	fig|196164.1.peg.1901.
PATRIC	21489949. VBICorEff9312_1888.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG299384.
OMA	ENGCEIM.
PhylomeDB	Q8FP84.
ProtClustDB	PRK12896.
Family and domain databases
InterPro	IPR001714. Pept_M24_MAP. IPR000994. Pept_M24_structural-domain. IPR002467. Pept_M24A_MAP1. [Graphical view]
Gene3D	G3DSA:3.90.230.10. Peptidase_M24_cat_core. 1 hit.
KO	K01265.
Pfam	PF00557. Peptidase_M24. 1 hit. [Graphical view]
PRINTS	PR00599. MAPEPTIDASE.
SUPFAM	SSF55920. Peptidase_M24_cat_core. 1 hit.
TIGRFAMs	TIGR00500. Met_pdase_I. 1 hit.
PROSITE	PS00680. MAP_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8FP84_COREF

Accession

Primary (citable) accession number: Q8FP84

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	December 14, 2011
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)