Reviewed, UniProtKB/Swiss-Prot Q8FP19 (ACYP_COREF)

Names and origin

Protein names

Recommended name:
    Acylphosphatase
    EC=3.6.1.7
Alternative name(s):
    Acylphosphate phosphohydrolase

Gene names

Name:	acyP
Ordered Locus Names:	CE1973

Organism

Corynebacterium efficiens [Complete proteome] [HAMAP]

Taxonomic identifier

152794 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	99 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	An acylphosphate + H2O = a carboxylate + phosphate. HAMAP MF_01450
Sequence similarities	Belongs to the acylphosphatase family. Contains 1 acylphosphatase-like domain.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	acylphosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 99	99	Acylphosphatase HAMAP MF_01450		PRO_0000326690
Regions
	Domain	10 – 99	90	Acylphosphatase-like
Sites
	Active site	25	1	By similarity
	Active site	43	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8FP19-1 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 0A553E3E3E152A10	FASTA	99	11,112
	10 20 30 40 50 60 MSMQPTDHIR LTAFVHGHVQ GVGFRWWTRS QALELGLAGS ATNLDDGRVC VVAEGPEDRC 70 80 90 RELLTRLGEQ PSRHRRVGTV STVIEQWSEP RGVEGFTER

References

[1]

"Comparative complete genome sequence analysis of the amino acid replacements responsible for the thermostability of Corynebacterium efficiens." Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S., Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T. Genome Res. 13:1572-1579(2003) [PubMed: 12840036] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000035 Genomic DNA. Translation: BAC18783.1.
RefSeq	NP_738583.1.
3D structure databases
HSSP	HSSP built from PDB template 2BJD based on UniProtKB Q97ZL0.
SMR	Q8FP19. Positions 7-99.
ModBase	Search...
Genome annotation databases
GeneID	1034693.
GenomeReviews	Gene locus CE1973 in contig BA000035_GR.
KEGG	cef:CE1973.
NMPDR	fig|196164.1.peg.1973.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG750266.
OMA	GRVCVVA.
PhylomeDB	Q8FP19.
Enzyme and pathway databases
BioCyc	CEFF196164:CE1973-MONOMER.
BRENDA	3.6.1.7. 277326.
Family and domain databases
HAMAP	MF_01450. Acylphosphatase. [Tree]
InterPro	IPR001792. Acylphosphatase-like. IPR017968. Acylphosphatase_CS. [Graphical view]
PANTHER	PTHR10029. Acylphosphatase. 1 hit.
Pfam	PF00708. Acylphosphatase. 1 hit. [Graphical view]
PROSITE	PS00150. ACYLPHOSPHATASE_1. 1 hit. PS00151. ACYLPHOSPHATASE_2. False negative. PS51160. ACYLPHOSPHATASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACYP_COREF

Accession

Primary (citable) accession number: Q8FP19

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	March 1, 2003
Last modified:	January 19, 2010
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)