Q8FNW4 (Q8FNW4_COREF) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative DNA polymerase III alpha subunit EMBL BAC18839.1

Gene names

Ordered Locus Names:

CE2029

Organism

Corynebacterium efficiens [Complete proteome] [HAMAP]

Taxonomic identifier

152794 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	1204 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). SAAS SAAS004013

Ontologies

Keywords
Biological process	DNA replication SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8FNW4 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: E26C9D77BD3F71BF	FASTA	1,204	133,527
	10 20 30 40 50 60 MSSRFLPPKS PARLSRMAKQ SSFVHLHNHT EYSMLDGMAK IDMLADEVNR QQMPAVGITD 70 80 90 100 110 120 HGNMYGSNAF YRKMTEAGVK PIIGIEAYLA PESRFNKERV RWGEPHQKSD DVSASGAYLH 130 140 150 160 170 180 QTMLAENATG LRNLFYLSSM ASYEGQLGKW PRMDAEIIAE RAEGIIATTG CPSGDVQTRL 190 200 210 220 230 240 RLGQFNEALE AAAMWQDIYG RDNYFLELMD HGLDIENRVR SELLEIGRKL NLPPLVTNDC 250 260 270 280 290 300 HYVLESQAQA HEAMLCVQTG KTLHDEDRFK FDGSGYYIKT AEQMRSLWDD TVPDGCDNTL 310 320 330 340 350 360 WIAERVQDYG EIWEEHPHDR MPVADVPEGH TPTSWLHHEV MAGLEDRFPG QQVPQEYIER 370 380 390 400 410 420 AEYEISVIDM KGYPSYFLIV AEIIKHARSI GIWVGPGRGS AAGALVAYAL TITNIDPIEH 430 440 450 460 470 480 GLLFERFLNP ERPSAPDIDI DFDDRRRGEM IRYAADRWGE DKIAQVITFG TVKTKQAIKD 490 500 510 520 530 540 SARVQFGQPG YQIADRITKV LPPPIMAKDI PLSGITDPEH ERYNEAGEVR ALIETDPDVR 550 560 570 580 590 600 KIYDTARGLE GVVRQAGVHA CAVIMSSQPL LECIPMWKRP ADGAYITGWD YPACEAIGLL 610 620 630 640 650 660 KMDFLGLRNL TVIGDAIENI KANRDGKVVD LENLSIEDEE TYKLLSRGET LGIFQLDGGG 670 680 690 700 710 720 MQELLKRMQP TGFNDIVAAL ALYRPGPMGV NAHWDYADRK NGRKPITPIH PELEEPLAEI 730 740 750 760 770 780 LGETYGLIVY QEQIMKISQK VANYTAGQAD GFRKAMGKKK PEVLAKEFAA FEAGMKANGF 790 800 810 820 830 840 SADAIKTLWD TILPFAGYAF NKSHAAGYGL VSFWTAYLKA HYAPEYMAAL LTSVGDNKDK 850 860 870 880 890 900 TAIYLADCRH LGIRVLSPDI NESALNFMPV GTDIRYGLGA IRNVGSEVVD SIIETRQSKG 910 920 930 940 950 960 MFRDFSDYLD KIDTLPCNKR ITESLIKAGA FDSLGHTRKG LMLVYEDAVD SVIATKKAAD 970 980 990 1000 1010 1020 KGQFDLFASF GAEAEDEVGG FFQIAVPDDK WDRKHELALE REMLGLYVSG HPLDGYEDAL 1030 1040 1050 1060 1070 1080 AAQIDTPLTT IIAGELRHGA EVTVGGIISG VDRRFSKKDG SPWAIVTMED HNGASVELLV 1090 1100 1110 1120 1130 1140 FNKVYSIVGS LIVEDNIILA KAHVSIRDDR MSLFCDDLRV PELGPGNGSG LPLRLTMRTD 1150 1160 1170 1180 1190 1200 QCTMTNISKL KQVLVGNRGE SDVYLNLVDG DSSTVMILGD HLRVTRSASL MGDLKATMGP GILG

References

[1]

"Comparative complete genome sequence analysis of the amino acid replacements responsible for the thermostability of Corynebacterium efficiens." Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S., Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T. Genome Res. 13:1572-1579(2003) [PubMed: 12840036] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000035 Genomic DNA. Translation: BAC18839.1.
RefSeq	NP_738639.1. NC_004369.1.
3D structure databases
ProteinModelPortal	Q8FNW4.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1034771.
GenomeReviews	Gene locus CE2029 in contig BA000035_GR.
KEGG	cef:CE2029.
NMPDR	fig|196164.1.peg.2029.
PATRIC	21490191. VBICorEff9312_2010.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG734490.
OMA	RVLQMPY.
PhylomeDB	Q8FNW4.
ProtClustDB	PRK05673.
Family and domain databases
InterPro	IPR011708. DNA_pol3_alpha. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K02337.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q8FNW4_COREF

Accession

Primary (citable) accession number: Q8FNW4

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	December 14, 2011
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)