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Q8FNQ8

- COX4_COREF

UniProt

Q8FNQ8 - COX4_COREF

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Protein
Cytochrome c oxidase polypeptide 4
Gene
ctaF, CE2086
Organism
Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Part of cytochrome c oxidase, its function is unknown By similarity.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Oxidoreductase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c oxidase polypeptide 4 (EC:1.9.3.1)
    Alternative name(s):
    Cytochrome aa3 subunit 4
    Cytochrome c oxidase polypeptide IV
    Gene namesi
    Name:ctaF
    Ordered Locus Names:CE2086
    OrganismiCorynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
    Taxonomic identifieri196164 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
    ProteomesiUP000001409: Chromosome

    Subcellular locationi

    Topology

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei7 – 2721Helical; Reviewed prediction
    Add
    BLAST
    Transmembranei40 – 6021Helical; Reviewed prediction
    Add
    BLAST
    Transmembranei83 – 10321Helical; Reviewed prediction
    Add
    BLAST
    Transmembranei105 – 12521Helical; Reviewed prediction
    Add
    BLAST

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell
    Complete GO annotation...

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 143143Cytochrome c oxidase polypeptide 4
    PRO_0000220014Add
    BLAST

    Interactioni

    Subunit structurei

    Associates with subunits I, II and III to form cytochrome c oxidase By similarity.

    Protein-protein interaction databases

    STRINGi196164.CE2086.

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    HOGENOMiHOG000237887.
    OMAiGAKLFYG.
    OrthoDBiEOG63FW2X.

    Family and domain databases

    InterProiIPR021050. Cyt_c_oxidase_su4_actinobac.
    [Graphical view]
    PfamiPF12270. Cyt_c_ox_IV. 1 hit.
    [Graphical view]
    PIRSFiPIRSF017385. CtaF. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8FNQ8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKSSSKIMYG LTVFLAAMAV IYIFGTMYVD DRGSVMGLEW VGATALVLST    50
    ALTLMLGVYI HITERRTDVL PEDWEEAEVA DKAGTLGFFS PGSIWPAAMS 100
    GAVGLLGFGI IFMHYWLILV GALALTYTIA KLNFQYGVPR EKH 143
    Length:143
    Mass (Da):15,646
    Last modified:March 1, 2003 - v1
    Checksum:i531814488D5F39DC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000035 Genomic DNA. Translation: BAC18896.1.
    RefSeqiNP_738696.1. NC_004369.1.

    Genome annotation databases

    EnsemblBacteriaiBAC18896; BAC18896; BAC18896.
    GeneIDi1034873.
    KEGGicef:CE2086.
    PATRICi21490307. VBICorEff9312_2068.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000035 Genomic DNA. Translation: BAC18896.1 .
    RefSeqi NP_738696.1. NC_004369.1.

    3D structure databases

    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 196164.CE2086.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAC18896 ; BAC18896 ; BAC18896 .
    GeneIDi 1034873.
    KEGGi cef:CE2086.
    PATRICi 21490307. VBICorEff9312_2068.

    Phylogenomic databases

    HOGENOMi HOG000237887.
    OMAi GAKLFYG.
    OrthoDBi EOG63FW2X.

    Family and domain databases

    InterProi IPR021050. Cyt_c_oxidase_su4_actinobac.
    [Graphical view ]
    Pfami PF12270. Cyt_c_ox_IV. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF017385. CtaF. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Comparative complete genome sequence analysis of the amino acid replacements responsible for the thermostability of Corynebacterium efficiens."
      Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S., Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T.
      Genome Res. 13:1572-1579(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395.

    Entry informationi

    Entry nameiCOX4_COREF
    AccessioniPrimary (citable) accession number: Q8FNQ8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 26, 2005
    Last sequence update: March 1, 2003
    Last modified: May 14, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

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