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Protein

Cytochrome c oxidase polypeptide 4

Gene

ctaF

Organism
Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of cytochrome c oxidase, its function is unknown.By similarity

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase polypeptide 4 (EC:1.9.3.1)
Alternative name(s):
Cytochrome aa3 subunit 4
Cytochrome c oxidase polypeptide IV
Gene namesi
Name:ctaF
Ordered Locus Names:CE2086
OrganismiCorynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
Taxonomic identifieri196164 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesCorynebacteriaceaeCorynebacterium
ProteomesiUP000001409 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei7 – 2721HelicalSequence AnalysisAdd
BLAST
Transmembranei40 – 6021HelicalSequence AnalysisAdd
BLAST
Transmembranei83 – 10321HelicalSequence AnalysisAdd
BLAST
Transmembranei105 – 12521HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 143143Cytochrome c oxidase polypeptide 4PRO_0000220014Add
BLAST

Interactioni

Subunit structurei

Associates with subunits I, II and III to form cytochrome c oxidase.By similarity

Protein-protein interaction databases

STRINGi196164.HMPREF0290_2122.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000237887.
OMAiGAKLFYG.
OrthoDBiEOG63FW2X.

Family and domain databases

InterProiIPR021050. Cyt_c_oxidase_su4_actinobac.
[Graphical view]
PfamiPF12270. Cyt_c_ox_IV. 1 hit.
[Graphical view]
PIRSFiPIRSF017385. CtaF. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8FNQ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSSSKIMYG LTVFLAAMAV IYIFGTMYVD DRGSVMGLEW VGATALVLST
60 70 80 90 100
ALTLMLGVYI HITERRTDVL PEDWEEAEVA DKAGTLGFFS PGSIWPAAMS
110 120 130 140
GAVGLLGFGI IFMHYWLILV GALALTYTIA KLNFQYGVPR EKH
Length:143
Mass (Da):15,646
Last modified:March 1, 2003 - v1
Checksum:i531814488D5F39DC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000035 Genomic DNA. Translation: BAC18896.1.
RefSeqiWP_006768088.1. NZ_GG700683.1.

Genome annotation databases

EnsemblBacteriaiBAC18896; BAC18896; BAC18896.
KEGGicef:CE2086.
PATRICi21490307. VBICorEff9312_2068.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000035 Genomic DNA. Translation: BAC18896.1.
RefSeqiWP_006768088.1. NZ_GG700683.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi196164.HMPREF0290_2122.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC18896; BAC18896; BAC18896.
KEGGicef:CE2086.
PATRICi21490307. VBICorEff9312_2068.

Phylogenomic databases

HOGENOMiHOG000237887.
OMAiGAKLFYG.
OrthoDBiEOG63FW2X.

Family and domain databases

InterProiIPR021050. Cyt_c_oxidase_su4_actinobac.
[Graphical view]
PfamiPF12270. Cyt_c_ox_IV. 1 hit.
[Graphical view]
PIRSFiPIRSF017385. CtaF. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Comparative complete genome sequence analysis of the amino acid replacements responsible for the thermostability of Corynebacterium efficiens."
    Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S., Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T.
    Genome Res. 13:1572-1579(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395.

Entry informationi

Entry nameiCOX4_COREF
AccessioniPrimary (citable) accession number: Q8FNQ8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: March 1, 2003
Last modified: July 22, 2015
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.