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Q8FNQ8

- COX4_COREF

UniProt

Q8FNQ8 - COX4_COREF

Protein

Cytochrome c oxidase polypeptide 4

Gene

ctaF

Organism
Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 66 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    Part of cytochrome c oxidase, its function is unknown.By similarity

    Catalytic activityi

    4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

    GO - Molecular functioni

    1. cytochrome-c oxidase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Oxidoreductase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c oxidase polypeptide 4 (EC:1.9.3.1)
    Alternative name(s):
    Cytochrome aa3 subunit 4
    Cytochrome c oxidase polypeptide IV
    Gene namesi
    Name:ctaF
    Ordered Locus Names:CE2086
    OrganismiCorynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
    Taxonomic identifieri196164 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
    ProteomesiUP000001409: Chromosome

    Subcellular locationi

    Cell membrane By similarity; Multi-pass membrane protein By similarity

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 143143Cytochrome c oxidase polypeptide 4PRO_0000220014Add
    BLAST

    Interactioni

    Subunit structurei

    Associates with subunits I, II and III to form cytochrome c oxidase.By similarity

    Protein-protein interaction databases

    STRINGi196164.CE2086.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei7 – 2721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei40 – 6021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei83 – 10321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei105 – 12521HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    HOGENOMiHOG000237887.
    OMAiGAKLFYG.
    OrthoDBiEOG63FW2X.

    Family and domain databases

    InterProiIPR021050. Cyt_c_oxidase_su4_actinobac.
    [Graphical view]
    PfamiPF12270. Cyt_c_ox_IV. 1 hit.
    [Graphical view]
    PIRSFiPIRSF017385. CtaF. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8FNQ8-1 [UniParc]FASTAAdd to Basket

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    MKSSSKIMYG LTVFLAAMAV IYIFGTMYVD DRGSVMGLEW VGATALVLST    50
    ALTLMLGVYI HITERRTDVL PEDWEEAEVA DKAGTLGFFS PGSIWPAAMS 100
    GAVGLLGFGI IFMHYWLILV GALALTYTIA KLNFQYGVPR EKH 143
    Length:143
    Mass (Da):15,646
    Last modified:March 1, 2003 - v1
    Checksum:i531814488D5F39DC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000035 Genomic DNA. Translation: BAC18896.1.
    RefSeqiNP_738696.1. NC_004369.1.

    Genome annotation databases

    EnsemblBacteriaiBAC18896; BAC18896; BAC18896.
    GeneIDi1034873.
    KEGGicef:CE2086.
    PATRICi21490307. VBICorEff9312_2068.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000035 Genomic DNA. Translation: BAC18896.1 .
    RefSeqi NP_738696.1. NC_004369.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 196164.CE2086.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAC18896 ; BAC18896 ; BAC18896 .
    GeneIDi 1034873.
    KEGGi cef:CE2086.
    PATRICi 21490307. VBICorEff9312_2068.

    Phylogenomic databases

    HOGENOMi HOG000237887.
    OMAi GAKLFYG.
    OrthoDBi EOG63FW2X.

    Family and domain databases

    InterProi IPR021050. Cyt_c_oxidase_su4_actinobac.
    [Graphical view ]
    Pfami PF12270. Cyt_c_ox_IV. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF017385. CtaF. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Comparative complete genome sequence analysis of the amino acid replacements responsible for the thermostability of Corynebacterium efficiens."
      Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S., Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T.
      Genome Res. 13:1572-1579(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395.

    Entry informationi

    Entry nameiCOX4_COREF
    AccessioniPrimary (citable) accession number: Q8FNQ8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 26, 2005
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3