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Protein

Uronate isomerase

Gene

uxaC

Organism
Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:CE2377
OrganismiCorynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
Taxonomic identifieri196164 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesCorynebacteriaceaeCorynebacterium
Proteomesi
  • UP000001409 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001727691 – 469Uronate isomeraseAdd BLAST469

Interactioni

Protein-protein interaction databases

STRINGi196164.HMPREF0290_2417.

Structurei

3D structure databases

ProteinModelPortaliQ8FMX2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000238114.
KOiK01812.
OrthoDBiPOG091H07GL.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8FMX2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTSHAAHPD RLLPADPATR DIARRLLTYV EDLPIISPHG HLEASMFVKD
60 70 80 90 100
EPFADPTTLL ISPDHYLTRV LHSAGVDLAD LRVGGTEGKT PREAWRIFAS
110 120 130 140 150
NWDLYTGTAT GYWVEQEFEH VFGINPDRLS AENADDIYDE LSEILARPDF
160 170 180 190 200
RPRALAEQFN LEILATTDDP LDDLADHKAL AQDPTFSPRV LPTFRPDAYT
210 220 230 240 250
KMYNPGWAEK TTRLIDVAGD GKAGWEGYLQ AMRNRRQYFI DHGATSADHG
260 270 280 290 300
THDTDTTPLS HEDAQRILDK GLAGTATLAE MRAFEANTTY RFAEMCQDDG
310 320 330 340 350
LVMTLHPGVY RNHSASAQKK FGNDIGADIP FQLEYTRGLR PLLSDFGENK
360 370 380 390 400
DFHFVMFTID ETVFSREVAP LAGYYPAAYV GAPWWFIDEI DAMNRFRSLT
410 420 430 440 450
TGTTGFSRYS GFIDDTRAYC SIPARHNTSR RVEANYLARL VAEHRISETR
460
ASEIIVDLID ASPRRVFKL
Length:469
Mass (Da):52,801
Last modified:July 11, 2003 - v2
Checksum:i657735F75D85DA4F
GO

Sequence cautioni

The sequence BAC19187 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000035 Genomic DNA. Translation: BAC19187.1. Different initiation.
RefSeqiWP_006768383.1. NZ_GG700683.1.

Genome annotation databases

EnsemblBacteriaiBAC19187; BAC19187; BAC19187.
KEGGicef:CE2377.
PATRICi21490885. VBICorEff9312_2348.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000035 Genomic DNA. Translation: BAC19187.1. Different initiation.
RefSeqiWP_006768383.1. NZ_GG700683.1.

3D structure databases

ProteinModelPortaliQ8FMX2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi196164.HMPREF0290_2417.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC19187; BAC19187; BAC19187.
KEGGicef:CE2377.
PATRICi21490885. VBICorEff9312_2348.

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000238114.
KOiK01812.
OrthoDBiPOG091H07GL.

Enzyme and pathway databases

UniPathwayiUPA00246.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUXAC_COREF
AccessioniPrimary (citable) accession number: Q8FMX2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2003
Last sequence update: July 11, 2003
Last modified: September 7, 2016
This is version 66 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.