ID   NTPA_COREF              Reviewed;         221 AA.
AC   Q8FMU9;
DT   26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   16-JUN-2009, entry version 31.
DE   RecName: Full=Nucleoside-triphosphatase;
DE            EC=3.6.1.15;
DE   AltName: Full=Nucleoside triphosphate phosphohydrolase;
DE            Short=NTPase;
GN   OrderedLocusNames=CE2400;
OS   Corynebacterium efficiens.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Corynebacteriaceae; Corynebacterium.
OX   NCBI_TaxID=152794;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395;
RX   MEDLINE=22723752; PubMed=12840036; DOI=10.1101/gr.1285603;
RA   Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E.,
RA   Sugimoto S., Matsui K., Yamagishi A., Kikuchi H., Ikeo K.,
RA   Gojobori T.;
RT   "Comparative complete genome sequence analysis of the amino acid
RT   replacements responsible for the thermostability of Corynebacterium
RT   efficiens.";
RL   Genome Res. 13:1572-1579(2003).
CC   -!- FUNCTION: Hydrolyzes non-standard nucleotides such as XTP and
CC       dITP/ITP. Might exclude non-standard purines from DNA precursor
CC       pool, preventing thus incorporation into DNA and avoiding
CC       chromosomal lesions (By similarity).
CC   -!- CATALYTIC ACTIVITY: NTP + H(2)O = NDP + phosphate.
CC   -!- COFACTOR: Divalent cations (By similarity).
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the HAM1 NTPase family.
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DR   EMBL; BA000035; BAC19210.1; -; Genomic_DNA.
DR   RefSeq; NP_739010.1; -.
DR   HSSP; P52061; 1K7K.
DR   GeneID; 1034567; -.
DR   GenomeReviews; BA000035_GR; CE2400.
DR   KEGG; cef:CE2400; -.
DR   NMPDR; fig|196164.1.peg.2400; -.
DR   HOGENOM; Q8FMU9; -.
DR   OMA; Q8FMU9; VYTADWA.
DR   BioCyc; CEFF196164:CE2400-MON; -.
DR   BRENDA; 3.6.1.15; 277326.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:HAMAP.
DR   HAMAP; MF_01405; -; 1.
DR   InterPro; IPR002637; Ham1p-like.
DR   PANTHER; PTHR11067; Ham1p_like; 1.
DR   Pfam; PF01725; Ham1p_like; 1.
DR   TIGRFAMs; TIGR00042; Ham1p_like; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase.
FT   CHAIN         1    221       Nucleoside-triphosphatase.
FT                                /FTId=PRO_0000178158.
SQ   SEQUENCE   221 AA;  23800 MW;  CEFDF6BA87F9F8D5 CRC64;
     MNSSMHRRPP WESDMKLLVA SNNAKKLGEL QRILDQAGIE NVELLALADV PSYPEPVEDG
     RTFTENALIK ARAGASNTGL ITLADDSGLE VDALNGMPGV LSARWAGKHG NDQANNDLLL
     AQIADIPEEH RGAAFVSVCA IVTPDGREFV EEGRWHGTLL REPVGTNGFG YDPLFVPMEE
     SLIEGRDRSS AQLTAQEKDA LSHRGKALRA LVPAIAELAG Q
//