Reviewed, UniProtKB/Swiss-Prot Q8FMU6 (MURI_COREF)

Names and origin

Protein names

Recommended name:
    Glutamate racemase
    EC=5.1.1.3

Gene names

Name:	murI
Ordered Locus Names:	CE2403

Organism

Corynebacterium efficiens [Complete proteome] [HAMAP]

Taxonomic identifier

152794 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	273 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Provides the (R)-glutamate required for cell wall biosynthesis By similarity.
Catalytic activity	L-glutamate = D-glutamate. HAMAP MF_00258
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00258
Sequence similarities	Belongs to the aspartate/glutamate racemases family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: HAMAP regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	glutamate racemase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 273	273	Glutamate racemase HAMAP MF_00258		PRO_0000095467

Sequences

	Sequence		Length	Mass (Da)
	Q8FMU6-1 [UniParc]. Last modified April 11, 2003. Version 2. Checksum: 68DF4B5DB732ACD6	FASTA	273	29,305
	10 20 30 40 50 60 MIERPIPGAD APIGIFDSGV GGLTVARTII DQLPHESIIY IGDTANGPYG PLPIARVREH 70 80 90 100 110 120 ALRIADELVE RGCKMIVIAC NTASAAFLRD ARERYDVPVV EVILPAVRRA VAATRNGKVG 130 140 150 160 170 180 VIGTVGTINS GAYQDLFAAS PSIEVHAAAC PRFVDFVERG ITSGRQILNI AEGYLEPLQA 190 200 210 220 230 240 QGVDTLVLGC THYPLLSGVI QLAMGDHVTL VSSAEETAKD VLRILSQNDL LADPTMHPTP 250 260 270 TYSFESTGDP ELFSQLSRRF LGPVVTQIRH NMV

References

[1]

"Comparative complete genome sequence analysis of the amino acid replacements responsible for the thermostability of Corynebacterium efficiens." Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S., Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T. Genome Res. 13:1572-1579(2003) [PubMed: 12840036] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000035 Genomic DNA. Translation: BAC19213.1. Different initiation.
RefSeq	NP_739013.1.
3D structure databases
HSSP	HSSP built from PDB template 1B74 based on UniProtKB P56868.
ModBase	Search...
Genome annotation databases
GeneID	1032089.
GenomeReviews	Gene locus CE2403 in contig BA000035_GR.
KEGG	cef:CE2403.
NMPDR	fig|196164.1.peg.2403.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8FMU6.
Enzyme and pathway databases
BioCyc	CEFF196164:CE2403-MON.
BRENDA	5.1.1.3. 277326.
Family and domain databases
HAMAP	MF_00258. [Tree]
InterPro	IPR015942. Asp/Glu/hydantoin_racemase. IPR001920. Asp/Glu_race. IPR018187. Asp/Glu_racemase_AS. IPR004391. Glu_race. [Graphical view]
Gene3D	G3DSA:3.40.50.1860. Asp/Glu_race. 1 hit.
Pfam	PF01177. Asp_Glu_race. 1 hit. [Graphical view]
TIGRFAMs	TIGR00067. glut_race. 1 hit.
PROSITE	PS00923. ASP_GLU_RACEMASE_1. 1 hit. PS00924. ASP_GLU_RACEMASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MURI_COREF

Accession

Primary (citable) accession number: Q8FMU6

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 11, 2003
Last sequence update:	April 11, 2003
Last modified:	September 22, 2009
This is version 39 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)