ID   ACKA_COREF              Reviewed;         398 AA.
AC   Q8FMB7;
DT   25-MAR-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   16-JUN-2009, entry version 38.
DE   RecName: Full=Acetate kinase;
DE            EC=2.7.2.1;
DE   AltName: Full=Acetokinase;
GN   Name=ackA; OrderedLocusNames=CE2590;
OS   Corynebacterium efficiens.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Corynebacteriaceae; Corynebacterium.
OX   NCBI_TaxID=152794;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395;
RX   MEDLINE=22723752; PubMed=12840036; DOI=10.1101/gr.1285603;
RA   Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E.,
RA   Sugimoto S., Matsui K., Yamagishi A., Kikuchi H., Ikeo K.,
RA   Gojobori T.;
RT   "Comparative complete genome sequence analysis of the amino acid
RT   replacements responsible for the thermostability of Corynebacterium
RT   efficiens.";
RL   Genome Res. 13:1572-1579(2003).
CC   -!- CATALYTIC ACTIVITY: ATP + acetate = ADP + acetyl phosphate.
CC   -!- CATALYTIC ACTIVITY: ATP + propanoate = ADP + propanoyl phosphate.
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; acetyl-CoA
CC       biosynthesis; acetyl-CoA from acetate: step 1/2.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the acetokinase family.
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DR   EMBL; BA000035; BAC19400.1; -; Genomic_DNA.
DR   RefSeq; NP_739200.1; -.
DR   HSSP; P38502; 1G99.
DR   GeneID; 1034166; -.
DR   GenomeReviews; BA000035_GR; CE2590.
DR   KEGG; cef:CE2590; -.
DR   NMPDR; fig|196164.1.peg.2590; -.
DR   HOGENOM; Q8FMB7; -.
DR   OMA; Q8FMB7; PHLKDKN.
DR   BioCyc; CEFF196164:CE2590-MON; -.
DR   BRENDA; 2.7.2.1; 277326.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008776; F:acetate kinase activity; IEA:HAMAP.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006082; P:organic acid metabolic process; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:HAMAP.
DR   HAMAP; MF_00020; -; 1.
DR   InterPro; IPR000890; Acetate_kin.
DR   InterPro; IPR004372; AckA.
DR   PANTHER; PTHR21060; Acetate_kin; 1.
DR   PANTHER; PTHR21060:SF11; AckA; 1.
DR   Pfam; PF00871; Acetate_kinase; 1.
DR   PIRSF; PIRSF000722; Acetate_prop_kin; 1.
DR   PRINTS; PR00471; ACETATEKNASE.
DR   TIGRFAMs; TIGR00016; ackA; 1.
DR   PROSITE; PS01075; ACETATE_KINASE_1; 1.
DR   PROSITE; PS01076; ACETATE_KINASE_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; Kinase; Nucleotide-binding;
KW   Transferase.
FT   CHAIN         1    398       Acetate kinase.
FT                                /FTId=PRO_0000107552.
SQ   SEQUENCE   398 AA;  43057 MW;  517A21CF3001279F CRC64;
     MALALVLNSG SSSIKFQLVN PANHATDDPF VSGLVEQIGE KMGRIILKIE GEKVVKEAPI
     ADHSAGLSMS FDLMTEHGCG PSQVDIIAVG HRVVHGGILF SAPELITDEI VEMIRDLIPL
     APLHNPANID GIEVARRILP DVPHVAVFDT GFFHSLPPAA ALYAINKDVA AEYGIRRYGF
     HGTSHEYVSS RVVDLMDKPA EEINTITFHL GNGASMAAVK GGVAVDTSMG MTPLAGLVMG
     TRTGDIDPGV VFHLARNANM SIDEIDNLMN KKSGVKGLSG VNDFRELHQM IEDGDQDAWS
     AYNIYIHQLR RYLGSYMVAL GRVDCLVFTA GVGENAHFVR EDALAGLEMY GIKVDPERNK
     LPNDGPRLIS TDDSTVKVFV IPTNEELAIA RYSAKFAE
//