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Q8FM44

- DCD_COREF

UniProt

Q8FM44 - DCD_COREF

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Protein
Deoxycytidine triphosphate deaminase
Gene
dcd, CE2663
Organism
Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

dCTP + H2O = dUTP + NH3.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. dCTP deaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. dUMP biosynthetic process Source: UniProtKB-UniPathway
  2. dUTP biosynthetic process Source: InterPro
  3. pyrimidine ribonucleotide biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Nucleotide metabolism

Enzyme and pathway databases

BioCyciCEFF196164:GJW8-2718-MONOMER.
UniPathwayiUPA00610; UER00665.

Names & Taxonomyi

Protein namesi
Recommended name:
Deoxycytidine triphosphate deaminase (EC:3.5.4.13)
Short name:
dCTP deaminase
Gene namesi
Name:dcd
Ordered Locus Names:CE2663
OrganismiCorynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
Taxonomic identifieri196164 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
ProteomesiUP000001409: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 193193Deoxycytidine triphosphate deaminaseUniRule annotation
PRO_0000155981Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi196164.CE2663.

Structurei

3D structure databases

ProteinModelPortaliQ8FM44.
SMRiQ8FM44. Positions 1-186.

Family & Domainsi

Sequence similaritiesi

Belongs to the dCTP deaminase family.

Phylogenomic databases

HOGENOMiHOG000228601.
KOiK01494.
OrthoDBiEOG67DPKR.

Family and domain databases

Gene3Di2.70.40.10. 1 hit.
HAMAPiMF_00146. dCTP_deaminase.
InterProiIPR011962. dCTP_deam.
IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
[Graphical view]
PfamiPF00692. dUTPase. 1 hit.
[Graphical view]
SUPFAMiSSF51283. SSF51283. 1 hit.
TIGRFAMsiTIGR02274. dCTP_deam. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8FM44-1 [UniParc]FASTAAdd to Basket

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MLLSDRDIRK SIDSGDLGID PFDPLLIQPS SIDVRMDRYF RVFNNSKYTH    50
IDPKLNQDEL TSLVEVADGD PFVLHPGEFV LAATLEKFTL PHHLAGRLEG 100
KSSLGRLGLL THSTAGFIDP GFSGHITLEL SNVANLPITL WPGMKVGQLA 150
LFMMSSPAET PYGSGSLGSK YQGQRGPTPS KGYLNFSSEQ DSD 193
Length:193
Mass (Da):21,064
Last modified:April 23, 2003 - v2
Checksum:i4040C9DBC70EC4D2
GO

Sequence cautioni

The sequence BAC19473.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000035 Genomic DNA. Translation: BAC19473.1. Different initiation.
RefSeqiNP_739273.2. NC_004369.1.

Genome annotation databases

EnsemblBacteriaiBAC19473; BAC19473; BAC19473.
GeneIDi1033851.
KEGGicef:CE2663.
PATRICi21491479. VBICorEff9312_2633.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000035 Genomic DNA. Translation: BAC19473.1 . Different initiation.
RefSeqi NP_739273.2. NC_004369.1.

3D structure databases

ProteinModelPortali Q8FM44.
SMRi Q8FM44. Positions 1-186.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 196164.CE2663.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAC19473 ; BAC19473 ; BAC19473 .
GeneIDi 1033851.
KEGGi cef:CE2663.
PATRICi 21491479. VBICorEff9312_2633.

Phylogenomic databases

HOGENOMi HOG000228601.
KOi K01494.
OrthoDBi EOG67DPKR.

Enzyme and pathway databases

UniPathwayi UPA00610 ; UER00665 .
BioCyci CEFF196164:GJW8-2718-MONOMER.

Family and domain databases

Gene3Di 2.70.40.10. 1 hit.
HAMAPi MF_00146. dCTP_deaminase.
InterProi IPR011962. dCTP_deam.
IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
[Graphical view ]
Pfami PF00692. dUTPase. 1 hit.
[Graphical view ]
SUPFAMi SSF51283. SSF51283. 1 hit.
TIGRFAMsi TIGR02274. dCTP_deam. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Comparative complete genome sequence analysis of the amino acid replacements responsible for the thermostability of Corynebacterium efficiens."
    Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S., Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T.
    Genome Res. 13:1572-1579(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395.

Entry informationi

Entry nameiDCD_COREF
AccessioniPrimary (citable) accession number: Q8FM44
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 23, 2003
Last sequence update: April 23, 2003
Last modified: June 11, 2014
This is version 64 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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