Q8FL88 (ARAB_ECOL6) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribulokinase
EC=2.7.1.16

Gene names

Name:	araB
Ordered Locus Names:	c0075

Organism

Escherichia coli O6 [Complete proteome] [HAMAP]

Taxonomic identifier

217992 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	566 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate. HAMAP MF_00520
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 2/3. HAMAP MF_00520
Sequence similarities	Belongs to the ribulokinase family.

Ontologies

Keywords
Biological process	Arabinose catabolism Carbohydrate metabolism
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	L-arabinose catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ribulokinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 566	565	Ribulokinase HAMAP MF_00520		PRO_0000198359

Sequences

	Sequence		Length	Mass (Da)
	Q8FL88 [UniParc]. Last modified January 23, 2007. Version 3. Checksum: 1B75BE723595BE3A	FASTA	566	61,279
	10 20 30 40 50 60 MAIAIGLDFG SDSVRALAVD CATGEEIATS VEWYPRWQNG QFCDAPNNQF RHHPRDYIES 70 80 90 100 110 120 MEAALKTVLA ELSVEQRAAV VGIGVDTTGS TPAPIDADGN VLALRPEFAE NPNAMFVLWK 130 140 150 160 170 180 DHTAVEEAEE ITRLCHAPGN VDYSRYIGGI YSSEWFWAKI LHITRQDNAV AQSAASWIEL 190 200 210 220 230 240 CDWVPALLSG TTRPQDIRRG RCSAGHKSLW HESWGGLPPA SFFDELDPIL NRHLPSPLFT 250 260 270 280 290 300 ETWTADIPVG TLCPEWAQRL GLPESVVISG GAFDCHMGAV GAGAQPNALV KVIGTSTCDI 310 320 330 340 350 360 LIADKQSVGE RAVKGICGQV DGSVVPGFIG LEAGQSAFGD IYAWFGRVLG WPLEQLAAQH 370 380 390 400 410 420 PELKEQINAS QKQLLPALTE AWAKNPSLDH LPVVLDWFNG RRTPNANQRL KGVITDLNLA 430 440 450 460 470 480 TDAPLLFGGL IAATAFGARA IMECFTAQGI AVNNVMALGG IARKNQVIMQ ACCDVLNRPL 490 500 510 520 530 540 QIVASDQCCA LGAAIFAAVA AKVHADIPSA QQKMASAVEK TLQPRNEQAQ RFEQLYRRYQ 550 560 QWAMSAEQHY LPTSAPAQAD QAVPTL

References

[1]

"Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli." Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D., Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F., Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T., Donnenberg M.S., Blattner F.R. Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002) [PubMed: 12471157] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: O6:H1 / CFT073 / ATCC 700928 / UPEC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014075 Genomic DNA. Translation: AAN78571.1.
RefSeq	NP_752027.1. NC_004431.1.
3D structure databases
ProteinModelPortal	Q8FL88.
SMR	Q8FL88. Positions 2-558.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000042271; EBESCP00000040620; EBESCG00000041321.
GeneID	1040445.
GenomeReviews	Gene locus c0075 in contig AE014075_GR.
KEGG	ecc:c0075.
NMPDR	fig|199310.1.peg.71.
PATRIC	18278233. VBIEscCol75197_0072.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000009229.
HOGENOM	HBG312681.
OMA	NGRRTPD.
ProtClustDB	PRK04123.
Family and domain databases
HAMAP	MF_00520. Ribulokinase. [Tree]
InterPro	IPR000577. Carb_kinase_FGGY. IPR018485. Carb_kinase_FGGY_C. IPR018484. Carb_kinase_FGGY_N. IPR005929. L_ribulokin. [Graphical view]
KO	K00853.
PANTHER	PTHR10196. FGGY_kin. 1 hit.
Pfam	PF02782. FGGY_C. 1 hit. PF00370. FGGY_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR01234. L-ribulokinase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ARAB_ECOL6

Accession

Primary (citable) accession number: Q8FL88

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 30, 2003
Last sequence update:	January 23, 2007
Last modified:	January 25, 2012
This is version 51 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program