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Q8FKC6

- ACPH_ECOL6

UniProt

Q8FKC6 - ACPH_ECOL6

Protein

Acyl carrier protein phosphodiesterase

Gene

acpH

Organism
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 65 (01 Oct 2014)
      Sequence version 2 (07 Mar 2006)
      Previous versions | rss
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    • Comment

    Functioni

    Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.UniRule annotation

    Catalytic activityi

    Holo-[acyl-carrier-protein] + H2O = 4'-phosphopantetheine + apo-[acyl-carrier-protein].UniRule annotation

    GO - Molecular functioni

    1. [acyl-carrier-protein] phosphodiesterase activity Source: UniProtKB-EC

    GO - Biological processi

    1. fatty acid biosynthetic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acyl carrier protein phosphodiesteraseUniRule annotation (EC:3.1.4.14UniRule annotation)
    Short name:
    ACP phosphodiesteraseUniRule annotation
    Gene namesi
    Name:acpHUniRule annotation
    Ordered Locus Names:c0514
    OrganismiEscherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
    Taxonomic identifieri199310 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000001410: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 193193Acyl carrier protein phosphodiesterasePRO_0000226267Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi199310.c0514.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the AcpH family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000275880.
    KOiK08682.
    OMAiWLHRQID.
    OrthoDBiEOG6K6V7H.

    Family and domain databases

    HAMAPiMF_01950. AcpH.
    InterProiIPR007431. ACP_phosphodiesterase.
    IPR023491. ACP_phosphodiesterase_gpbac.
    [Graphical view]
    PfamiPF04336. DUF479. 1 hit.
    [Graphical view]
    PIRSFiPIRSF011489. DUF479. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8FKC6-1 [UniParc]FASTAAdd to Basket

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    MNFLAHLHLA HLAESSLSGN LLADFVRGNP EESFPPDVVA GIHMHRRIDV    50
    LTDNLPEVRE AREWFRNETR RVAPITLDVM WDHFLSRHWS QLSPDFPLQE 100
    FTCYAREQVM TILPDSPQRF INLNNYLWSE QWLVRYRDMD FIQSVLNGMA 150
    SRRPRLDALR DSWYDLDAHY DALETRFWQF YPRMMEQASR KAL 193
    Length:193
    Mass (Da):23,052
    Last modified:March 7, 2006 - v2
    Checksum:iC02716160F51E8B3
    GO

    Sequence cautioni

    The sequence AAN78992.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014075 Genomic DNA. Translation: AAN78992.1. Different initiation.
    RefSeqiNP_752448.2. NC_004431.1.

    Genome annotation databases

    EnsemblBacteriaiAAN78992; AAN78992; c0514.
    GeneIDi1036110.
    KEGGiecc:c0514.
    PATRICi18279074. VBIEscCol75197_0482.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014075 Genomic DNA. Translation: AAN78992.1 . Different initiation.
    RefSeqi NP_752448.2. NC_004431.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 199310.c0514.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAN78992 ; AAN78992 ; c0514 .
    GeneIDi 1036110.
    KEGGi ecc:c0514.
    PATRICi 18279074. VBIEscCol75197_0482.

    Phylogenomic databases

    HOGENOMi HOG000275880.
    KOi K08682.
    OMAi WLHRQID.
    OrthoDBi EOG6K6V7H.

    Family and domain databases

    HAMAPi MF_01950. AcpH.
    InterProi IPR007431. ACP_phosphodiesterase.
    IPR023491. ACP_phosphodiesterase_gpbac.
    [Graphical view ]
    Pfami PF04336. DUF479. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF011489. DUF479. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CFT073 / ATCC 700928 / UPEC.

    Entry informationi

    Entry nameiACPH_ECOL6
    AccessioniPrimary (citable) accession number: Q8FKC6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 7, 2006
    Last sequence update: March 7, 2006
    Last modified: October 1, 2014
    This is version 65 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3