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Protein

Fructose-6-phosphate aldolase 1

Gene

fsaA

Organism
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the reversible formation of fructose 6-phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction.By similarity

Catalytic activityi

D-fructose 6-phosphate = glycerone + D-glyceraldehyde 3-phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei85Schiff-base intermediate with substrateBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
Biological processCarbohydrate metabolism
LigandSchiff base

Names & Taxonomyi

Protein namesi
Recommended name:
Fructose-6-phosphate aldolase 1 (EC:4.1.2.-)
Gene namesi
Name:fsaA
Synonyms:fsa, mipB
Ordered Locus Names:c0910
OrganismiEscherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Taxonomic identifieri199310 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000001410 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001736441 – 220Fructose-6-phosphate aldolase 1Add BLAST220

Interactioni

Subunit structurei

Homodecamer.By similarity

Protein-protein interaction databases

STRINGi199310.c0910.

Structurei

3D structure databases

ProteinModelPortaliQ8FJL3.
SMRiQ8FJL3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the transaldolase family. Type 3A subfamily.Curated

Phylogenomic databases

eggNOGiENOG4107T9Z. Bacteria.
COG0176. LUCA.
HOGENOMiHOG000226075.
KOiK08313.
OMAiVRHPMHV.

Family and domain databases

CDDicd00956. Transaldolase_FSA. 1 hit.
Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00496. F6P_aldolase. 1 hit.
InterProiView protein in InterPro
IPR013785. Aldolase_TIM.
IPR023001. F6P_aldolase.
IPR001585. TAL/FSA.
IPR004731. Transaldolase_3B/F6P_aldolase.
IPR018225. Transaldolase_AS.
IPR033919. TSA/FSA_arc/bac.
PANTHERiPTHR10683. PTHR10683. 1 hit.
PfamiView protein in Pfam
PF00923. TAL_FSA. 1 hit.
TIGRFAMsiTIGR00875. fsa_talC_mipB. 1 hit.
PROSITEiView protein in PROSITE
PS01054. TRANSALDOLASE_1. 1 hit.
PS00958. TRANSALDOLASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8FJL3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELYLDTSDV VAVTALSRIF PLAGVTTNPS IIAAGKKPLE VVLPQLHEAM
60 70 80 90 100
GGQGRLFAQV MATTAEGMVN DARKLRSIIA DIVVKVPVTA EGLAAIKMLK
110 120 130 140 150
AEGIPTLGTA VYGAAQGLLS ALAGAEYVAP YVNRIDAQGG SGIQTVTDLH
160 170 180 190 200
QLLKMHAPQA KVLAASFKTP RQALDCLLAG CESITLPLDV AQQMISYPAV
210 220
DAAVAKFEQD WLGAFGRTSI
Length:220
Mass (Da):23,012
Last modified:December 21, 2004 - v2
Checksum:i80AFBD95C850CB8B
GO

Sequence cautioni

The sequence AAN79383 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014075 Genomic DNA. Translation: AAN79383.1. Different initiation.
RefSeqiWP_001298570.1. NC_004431.1.

Genome annotation databases

EnsemblBacteriaiAAN79383; AAN79383; c0910.
KEGGiecc:c0910.

Similar proteinsi

Entry informationi

Entry nameiFSAA_ECOL6
AccessioniPrimary (citable) accession number: Q8FJL3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 21, 2004
Last sequence update: December 21, 2004
Last modified: October 25, 2017
This is version 88 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome