Reviewed, UniProtKB/Swiss-Prot Q8FJ93 (SSUD_ECOL6)

Names and origin

Protein names

Recommended name:
    Alkanesulfonate monooxygenase
    EC=1.14.14.5
Alternative name(s):
    FMNH2-dependent aliphatic sulfonate monooxygenase

Gene names

Name:	ssuD
Synonyms:	ycbN
Ordered Locus Names:	c1078

Organism

Escherichia coli O6 [Complete proteome] [HAMAP]

Taxonomic identifier

217992 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	381 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the desulfonation of aliphatic sulfonates By similarity.
Catalytic activity	An alkanesufonate (R-CH(2)-SO3H) + FMNH2 + O2 = an aldehyde (R-CHO) + FMN + sulfite + H2O. HAMAP MF_01229
Subunit structure	Homotetramer By similarity.
Miscellaneous	FMNH2 which is absolutely required for this enzymatic reaction, is provided by ssuE By similarity.
Sequence similarities	Belongs to the ssuD family.

Ontologies

Keywords
Ligand	FMN
Molecular function	Monooxygenase Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	alkanesulfonate monooxygenase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 381	380	Alkanesulfonate monooxygenase HAMAP MF_01229		PRO_0000216707

Sequences

	Sequence		Length	Mass (Da)
	Q8FJ93-1 [UniParc]. Last modified January 23, 2007. Version 3. Checksum: 6C12DE4275E9C7A9	FASTA	381	41,686
	10 20 30 40 50 60 MSLNMFWFLP THGDGHYLGT EEGSRPIDHG YLQQIAQAAD RLGYTGVLIP TGRSCEDAWL 70 80 90 100 110 120 VAASMIPVTQ RLKFLVALRP SVTSPTVAAR QAATLDRLSN GRALFNLVTG SDPQELAGDG 130 140 150 160 170 180 VFLDHSERYE ASAEFTQVWR RLLLGETVDF NGKHIHVRGA KLLFPPIQQP YPPLYFGGSS 190 200 210 220 230 240 DVAQELAAEQ VDLYLTWGEP PELVKEKIEH VRAKAAAHGR KIRFGVRLHV IVRETNDEAW 250 260 270 280 290 300 QAAERLISRL DDETIAKAQA AFARTDSVGQ QRMAALHNGK RDNLEISPNL WAGVGLVRGG 310 320 330 340 350 360 AGTALVGDGP TVAARINEYA ALGIDSFVLS GYPHLEEAYR VGELLFPHLD VAIPEIPQPQ 370 380 PLNPQGEAVA NDFIPRNVAQ S

References

[1]

"Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli." Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D., Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F., Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T., Donnenberg M.S., Blattner F.R. Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002) [PubMed: 12471157] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: O6:H1 / CFT073 / ATCC 700928 / UPEC.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014075 Genomic DNA. Translation: AAN79546.1.
RefSeq	NP_753003.1.
3D structure databases
HSSP	HSSP built from PDB template 1M41 based on UniProtKB P80645.
SMR	Q8FJ93. Positions 1-362.
ModBase	Search...
Genome annotation databases
GeneID	1038862.
GenomeReviews	Gene locus c1078 in contig AE014075_GR.
KEGG	ecc:c1078.
NMPDR	fig|199310.1.peg.1046.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8FJ93.
OMA	Q8FJ93. NIFWFLP.
Enzyme and pathway databases
BRENDA	1.14.14.5. 292881.
Family and domain databases
HAMAP	MF_01229. [Tree]
InterPro	IPR019911. Alkanesulfonate_mOase_FMN-dep. IPR016048. Luciferase-like_sub. [Graphical view]
Pfam	PF00296. Bac_luciferase. 1 hit. [Graphical view]
TIGRFAMs	TIGR03565. Alk_sulf_monoox. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SSUD_ECOL6

Accession

Primary (citable) accession number: Q8FJ93

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 6, 2003
Last sequence update:	January 23, 2007
Last modified:	June 16, 2009
This is version 38 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)