Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8FHD0

- Q8FHD0_ECOL6

UniProt

Q8FHD0 - Q8FHD0_ECOL6

Protein
Submitted name:

Hypothetical oxidoreductase ydfI

Gene

c1968

Organism
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi31 – 322NADImported
    Nucleotide bindingi58 – 603NADImported
    Nucleotide bindingi183 – 1842NADImported
    Nucleotide bindingi224 – 2263NADImported

    GO - Molecular functioni

    1. coenzyme binding Source: InterPro
    2. nucleotide binding Source: UniProtKB-KW
    3. oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Source: InterPro

    GO - Biological processi

    1. mannitol metabolic process Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseSAAS annotationImported

    Keywords - Ligandi

    NADSAAS annotationImported, Nucleotide-bindingImported

    Enzyme and pathway databases

    BioCyciECOL199310:C1968-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Hypothetical oxidoreductase ydfIImported (EC:1.-.-.-Imported)
    Gene namesi
    Ordered Locus Names:c1968Imported
    OrganismiEscherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)Imported
    Taxonomic identifieri199310 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000001410: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi199310.c1968.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4IM7X-ray1.90A1-486[»]
    ProteinModelPortaliQ8FHD0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000202982.
    KOiK00540.
    OMAiNFFRAHE.
    OrthoDBiEOG6X9MNH.

    Family and domain databases

    Gene3Di1.10.1040.10. 1 hit.
    3.40.50.720. 1 hit.
    InterProiIPR008927. 6-PGluconate_DH_C-like.
    IPR013328. DH_multihelical.
    IPR000669. Mannitol_DH.
    IPR013118. Mannitol_DH_C.
    IPR023027. Mannitol_DH_CS.
    IPR013131. Mannitol_DH_N.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PfamiPF01232. Mannitol_dh. 1 hit.
    PF08125. Mannitol_dh_C. 1 hit.
    [Graphical view]
    PRINTSiPR00084. MTLDHDRGNASE.
    SUPFAMiSSF48179. SSF48179. 1 hit.
    PROSITEiPS00974. MANNITOL_DHGENASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8FHD0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGNHLLSAKA TLPVYDRNNL APRIVHLGFG AFHRAHQGVY ADILATEHFS    50
    DWGYYEVNLI GGEQQIADLQ QQDNLYTVAE MSADAWTARV VGVVKKALHV 100
    QIDGLETVLA AMCEPQIAIV SLTITEKGYF HSPATGQLML DHPMVVADVQ 150
    NPHQPKTATG VIVEALARRK AAGLPAFTVM SCDNMPENGH VMRDVVTSYA 200
    QAIDVKLAQW IEDNVTFPST MVDRIVPAVT EDTLAKIEQL TGVRDAAGVA 250
    CEPFRQWVIE DNFVAGRPEW EKAGAELVSD VLPYEEMKLR MLNGSHSFLA 300
    YLGYLAGYQH INDCMEDEHY RHAAYTLMLQ EQAPTLKVQG VDLQDYANRL 350
    IERYSNPALR HRTWQIAMDG SQKLPQRMLD SVRWHLAHDS KFDLLALGVA 400
    GWMRYVGGVD EQGNPIEISD PLLPVIQKAV QSSAEGTARV QSLLAIKAIF 450
    GDDLPGNSLF TTKVTEAYLS LLAHGAKATV AKYSVK 486
    Length:486
    Mass (Da):53,702
    Last modified:March 1, 2003 - v1
    Checksum:i7D6E149E03B86F80
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014075 Genomic DNA. Translation: AAN80428.1.
    RefSeqiNP_753863.1. NC_004431.1.

    Genome annotation databases

    EnsemblBacteriaiAAN80428; AAN80428; c1968.
    GeneIDi1035921.
    KEGGiecc:c1968.
    PATRICi18281837. VBIEscCol75197_1837.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014075 Genomic DNA. Translation: AAN80428.1 .
    RefSeqi NP_753863.1. NC_004431.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4IM7 X-ray 1.90 A 1-486 [» ]
    ProteinModelPortali Q8FHD0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 199310.c1968.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAN80428 ; AAN80428 ; c1968 .
    GeneIDi 1035921.
    KEGGi ecc:c1968.
    PATRICi 18281837. VBIEscCol75197_1837.

    Phylogenomic databases

    HOGENOMi HOG000202982.
    KOi K00540.
    OMAi NFFRAHE.
    OrthoDBi EOG6X9MNH.

    Enzyme and pathway databases

    BioCyci ECOL199310:C1968-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1040.10. 1 hit.
    3.40.50.720. 1 hit.
    InterProi IPR008927. 6-PGluconate_DH_C-like.
    IPR013328. DH_multihelical.
    IPR000669. Mannitol_DH.
    IPR013118. Mannitol_DH_C.
    IPR023027. Mannitol_DH_CS.
    IPR013131. Mannitol_DH_N.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    Pfami PF01232. Mannitol_dh. 1 hit.
    PF08125. Mannitol_dh_C. 1 hit.
    [Graphical view ]
    PRINTSi PR00084. MTLDHDRGNASE.
    SUPFAMi SSF48179. SSF48179. 1 hit.
    PROSITEi PS00974. MANNITOL_DHGENASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CFT073 / ATCC 700928 / UPECImported.
    2. "Crystal structure of fructuronate reductase (ydfI) from E. coli CFT073 (EFI TARGET EFI-506389) complexed with NADH and D-mannonate."
      Imker H.J., Nair S.K., Gerlt J.A., Wichelecki S., Lukk T.
      Submitted (JAN-2013) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) IN COMPLEX WITH NAD.

    Entry informationi

    Entry nameiQ8FHD0_ECOL6
    AccessioniPrimary (citable) accession number: Q8FHD0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 86 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteomeImported

    External Data

    Dasty 3