Starvation sensing protein rspB - Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

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Q8FHC8 (Q8FHC8_ECOL6) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 78. History...

Clusters with 100%, 90%, 50% identity |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info Customize order

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Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info Customize order

Names and origin

Protein names

Submitted name:
Starvation sensing protein rspB EMBL AAN80430.1
EC=1.1.1.- EMBL AAN80430.1

Gene names

Name:	rspB EMBL AAN80430.1
Ordered Locus Names:	c1970

Organism

Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) [Complete proteome] [HAMAP]

Taxonomic identifier

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia ›

Protein attributes

Sequence length	347 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Cofactor	Zinc By similarity. RuleBase RU000467
Sequence similarities	Belongs to the zinc-containing alcohol dehydrogenase family. RuleBase RU000468

Ontologies

Keywords
Ligand	Metal-binding RuleBase RU000467 Zinc RuleBase RU000467
Molecular function	Oxidoreductase RuleBase RU000467 EMBL AAN80430.1
Technical term	3D-structure PDB 4ILK Complete proteome
Gene Ontology (GO)
Molecular_function	nucleotide binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

Q8FHC8 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 233C08AF3C1BF67A
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347

37,452

        10         20         30         40         50         60 
MELVRSKVMK SILIEKPNQL SIIEREIPTP SAGEVRVKVK LAGICGSDSH IYRGHNPFAK 

        70         80         90        100        110        120 
YPRVIGHEFF GVIDAVGEGV ESARVGERVA VDPVVSCGHC YPCSIGKPNV CTTLAVLGVH 

       130        140        150        160        170        180 
ADGGFSEYAV VPAKNAWKIP EAVADQYAVM IEPFTIAANV TGHGQPTEND TVLVYGAGPI 

       190        200        210        220        230        240 
GLTIVQVLKG VYNVKNVIVA DRIDERLEKA KESGADWAIN NSQTPLGESF AEKGIKPTLI 

       250        260        270        280        290        300 
IDAACHPSIL KEAVTLASPA ARIVLMGFSS EPSEVIQQGI TGKELSIFSS RLNANKFPVV 

       310        320        330        340 
IDWLSKGLIK PEKLITHTFD FQHVADAISL FELDQKHCCK VLLTFSE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli." Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D., Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F., Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T., Donnenberg M.S., Blattner F.R. Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CFT073 / ATCC 700928 / UPEC.
[2]	"Crystal structure of short chain alcohol dehydrogenase (rspB) from E. coli CFT073 (EFI TARGET EFI-506413) complexed with cofactor NADH." Wichelecki S., Lukk T., Imker H.J., Nair S.K., Gerlt J.A. Submitted (DEC-2012) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 9-347.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE014075 Genomic DNA. Translation: AAN80430.1.

RefSeq

NP_753865.2. NC_004431.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4ILK	X-ray	2.00	A/B	9-347	[»]

HSSP

HSSP built from PDB template 1E3J based on UniProtKB O96496.

ProteinModelPortal

ModBase

Protein-protein interaction databases

STRING

Protocols and materials databases

StructuralBiologyKnowledgebase

Genome annotation databases

EnsemblBacteria

AAN80430; AAN80430; c1970.

GeneID

KEGG

PATRIC

18281841. VBIEscCol75197_1839.

Organism-specific databases

CMR

Phylogenomic databases

HOGENOM

KO

OMA

ProtClustDB

Family and domain databases

Gene3D

3.40.50.720. 1 hit.

InterPro

IPR013149. ADH_C.
IPR013154. ADH_GroES-like.
IPR002085. ADH_SF_Zn-type.
IPR002328. ADH_Zn_CS.
IPR011032. GroES-like.
IPR016040. NAD(P)-bd_dom.
[Graphical view]

PANTHER

PTHR11695. PTHR11695. 1 hit.

Pfam

PF08240. ADH_N. 1 hit.
PF00107. ADH_zinc_N. 1 hit.
[Graphical view]

SUPFAM

SSF50129. GroES_like. 1 hit.

PROSITE

PS00059. ADH_ZINC. 1 hit.
[Graphical view]

ProtoNet

Entry information

Entry name

Q8FHC8_ECOL6

Accession

Primary (citable) accession number: Q8FHC8

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	May 1, 2013
This is version 78 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

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Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info