SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8FEE7

- FUCI_ECOL6

UniProt

Q8FEE7 - FUCI_ECOL6

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
L-fucose isomerase
Gene
fucI, c3371
Organism
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Converts the aldose L-fucose into the corresponding ketose L-fuculose By similarity.UniRule annotation

Catalytic activityi

L-fucopyranose = L-fuculose.UniRule annotation

Cofactori

Manganese By similarity.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei337 – 3371Proton acceptor By similarity
Metal bindingi337 – 3371Manganese By similarity
Active sitei361 – 3611Proton acceptor By similarity
Metal bindingi361 – 3611Manganese By similarity
Metal bindingi528 – 5281Manganese By similarity

GO - Molecular functioni

  1. L-fucose isomerase activity Source: UniProtKB-HAMAP
  2. manganese ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. L-fucose catabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Carbohydrate metabolism, Fucose metabolism

Keywords - Ligandi

Manganese, Metal-binding

Enzyme and pathway databases

BioCyciECOL199310:C3371-MONOMER.
UniPathwayiUPA00563; UER00624.

Names & Taxonomyi

Protein namesi
Recommended name:
L-fucose isomerase (EC:5.3.1.25)
Alternative name(s):
6-deoxy-L-galactose isomerase
FucIase
Gene namesi
Name:fucI
Ordered Locus Names:c3371
OrganismiEscherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Taxonomic identifieri199310 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000001410: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 591591L-fucose isomeraseUniRule annotation
PRO_0000204147Add
BLAST

Interactioni

Subunit structurei

Homohexamer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi199310.c3371.

Structurei

3D structure databases

ProteinModelPortaliQ8FEE7.
SMRiQ8FEE7. Positions 1-591.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000249674.
KOiK01818.
OMAiKEGQDYR.
OrthoDBiEOG6FJNCF.

Family and domain databases

Gene3Di3.20.14.10. 1 hit.
3.40.275.10. 1 hit.
3.40.50.1070. 1 hit.
HAMAPiMF_01254. Fucose_iso.
InterProiIPR004216. Fuc/Ara_isomerase_C.
IPR015888. Fuc_isomerase_C.
IPR012888. Fucose_iso_N1.
IPR005763. Fucose_isomerase.
IPR009015. Fucose_isomerase_N/cen.
IPR012889. Fucose_isomerase_N2.
[Graphical view]
PfamiPF02952. Fucose_iso_C. 1 hit.
PF07881. Fucose_iso_N1. 1 hit.
PF07882. Fucose_iso_N2. 1 hit.
[Graphical view]
SUPFAMiSSF50443. SSF50443. 1 hit.
SSF53743. SSF53743. 1 hit.
TIGRFAMsiTIGR01089. fucI. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8FEE7-1 [UniParc]FASTAAdd to Basket

« Hide

MKKISLPKIG IRPVIDGRRM GVRESLEEQT MNMAKATAAL LTEKLRHACG    50
ATVECVISDT CIAGMAEAAA CEEKFSSQNV GLTITVTPCW CYGSETIDMD 100
PTRPKAIWGF NGTERPGAVY LAAALAAHSQ KGIPAFSIYG HDVQDADDTS 150
IPADVEEKLL RFARAGLAVA SMKGKSYLSL GGVSMGIAGS IVDHNFFESW 200
LGMKVQAVDM TELRRRIDQK IYDEAELEMA LAWADKNFRY GEDENNKQYQ 250
RNAEQSRAVL RESLLMAMCI RDMMQGNSKL ADIGRVEESL GYNAIAAGFQ 300
GQRHWTDQYP NGDTAEAILN SSFDWNGVRK PFVVATENDS LNGVAMLMGH 350
QLTGTAQVFA DVRTYWSPEA IERVTGHKLD GLAEHGIIHL INSGSAALDG 400
SCKQRDSEGN PTMKPHWEIS QQEADACLAA TEWCPAIHEY FRGGGYSSRF 450
LTEGGVPFTM TRVNIIKGLG PVLQIAEGWS VELPKDVHDI LNKRTNSTWP 500
TTWFAPRLTG KGPFTDVYSV MANWGANHGV LTIGHVGADF ITLASMLRIP 550
VCMHNVEETK VYRPSAWAAH GMDIEGQDYR ACQNYGPLYK R 591
Length:591
Mass (Da):65,006
Last modified:March 1, 2003 - v1
Checksum:iE623EB489DA8B09E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014075 Genomic DNA. Translation: AAN81818.1.
RefSeqiNP_755248.1. NC_004431.1.

Genome annotation databases

EnsemblBacteriaiAAN81818; AAN81818; c3371.
GeneIDi1039222.
KEGGiecc:c3371.
PATRICi18284570. VBIEscCol75197_3174.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014075 Genomic DNA. Translation: AAN81818.1 .
RefSeqi NP_755248.1. NC_004431.1.

3D structure databases

ProteinModelPortali Q8FEE7.
SMRi Q8FEE7. Positions 1-591.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 199310.c3371.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN81818 ; AAN81818 ; c3371 .
GeneIDi 1039222.
KEGGi ecc:c3371.
PATRICi 18284570. VBIEscCol75197_3174.

Phylogenomic databases

HOGENOMi HOG000249674.
KOi K01818.
OMAi KEGQDYR.
OrthoDBi EOG6FJNCF.

Enzyme and pathway databases

UniPathwayi UPA00563 ; UER00624 .
BioCyci ECOL199310:C3371-MONOMER.

Family and domain databases

Gene3Di 3.20.14.10. 1 hit.
3.40.275.10. 1 hit.
3.40.50.1070. 1 hit.
HAMAPi MF_01254. Fucose_iso.
InterProi IPR004216. Fuc/Ara_isomerase_C.
IPR015888. Fuc_isomerase_C.
IPR012888. Fucose_iso_N1.
IPR005763. Fucose_isomerase.
IPR009015. Fucose_isomerase_N/cen.
IPR012889. Fucose_isomerase_N2.
[Graphical view ]
Pfami PF02952. Fucose_iso_C. 1 hit.
PF07881. Fucose_iso_N1. 1 hit.
PF07882. Fucose_iso_N2. 1 hit.
[Graphical view ]
SUPFAMi SSF50443. SSF50443. 1 hit.
SSF53743. SSF53743. 1 hit.
TIGRFAMsi TIGR01089. fucI. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CFT073 / ATCC 700928 / UPEC.

Entry informationi

Entry nameiFUCI_ECOL6
AccessioniPrimary (citable) accession number: Q8FEE7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: March 1, 2003
Last modified: May 14, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi