Q8FBS5 (RAVA_ECOL6) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
ATPase RavA
EC=3.6.3.-

Alternative name(s):
Regulatory ATPase variant A

Gene names

Name:	ravA
Ordered Locus Names:	c4674

Organism

Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) [Complete proteome] [HAMAP]

Taxonomic identifier

199310 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	498 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone By similarity. HAMAP-Rule MF_01625
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the RavA family.
Sequence caution	The sequence AAN83106.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	ATP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity Inferred from electronic annotation. Source: HAMAP hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 498	498	ATPase RavA HAMAP-Rule MF_01625		PRO_0000209372

Sequences

	Sequence		Length	Mass (Da)
	Q8FBS5 [UniParc]. Last modified January 10, 2006. Version 2. Checksum: F29ABD4C639311B6	FASTA	498	56,377
	10 20 30 40 50 60 MAHPHLLAER ISRLSSSLEK GLYERSHAIR LCLLAALSGE SVFLLGPPGI AKSLIARRLK 70 80 90 100 110 120 FAFQNARAFE YLMTRFSTPE EVFGPLSIQA LKDEGRYERL TSGYLPEAEI VFLDEIWKAG 130 140 150 160 170 180 PAILNTLLTA INERQFRNGA LVEKIPMRLL VAASNELPEA DSSLEALYDR MLIRLWLDKV 190 200 210 220 230 240 QDKANFRSML TSQQDENDNP VPASLQITDE EYERWQKEIG EITLPDHVFE LIFMLRQQLD 250 260 270 280 290 300 KLPDAPYVSD RRWKKAIRLL QASAFFSGRS AVAPVDLILL KDCLWYDAQS LNLIQQQIDV 310 320 330 340 350 360 LMTGHAWQQQ GMLTRLGAIV QRHLQLQQQQ SDKTALTVIR LGGIFSRRQQ YQLPVNVTAS 370 380 390 400 410 420 TLTLLLQKPL KLHDMEVVHI SFERSALEQW LSKGGEIRGK LNGIGFAQKL NLEVDSAQHL 430 440 450 460 470 480 VVRDVSLQGS TLALPGSLAE GLPGEIKQQL EELESDWRKQ HALFSEQQKC LFIPGDWLGR 490 IEASLQDVGA QIRQAQQC

References

[1]

"Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli." Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D., Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F., Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T., Donnenberg M.S., Blattner F.R. Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CFT073 / ATCC 700928 / UPEC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014075 Genomic DNA. Translation: AAN83106.1. Different initiation.
RefSeq	NP_756532.2. NC_004431.1.
3D structure databases
ProteinModelPortal	Q8FBS5.
SMR	Q8FBS5. Positions 21-182.
ModBase	Search...
Protein-protein interaction databases
STRING	199310.c4674.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAN83106; AAN83106; c4674.
GeneID	1040287.
KEGG	ecc:c4674.
PATRIC	18287027. VBIEscCol75197_4387.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000272029.
KO	K03924.
OMA	GMFSRKP.
ProtClustDB	PRK13531.
Family and domain databases
HAMAP	MF_01625. ATPase_RavA.
InterPro	IPR003593. AAA+_ATPase. IPR011704. ATPase_dyneun-rel_AAA. IPR023671. ATPase_RavA. IPR022547. ATPase_RavA_C. [Graphical view]
Pfam	PF07728. AAA_5. 1 hit. PF12592. DUF3763. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RAVA_ECOL6

Accession

Primary (citable) accession number: Q8FBS5

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 10, 2006
Last sequence update:	January 10, 2006
Last modified:	May 1, 2013
This is version 69 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program