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Q8FB16

- Q8FB16_ECOL6

UniProt

Q8FB16 - Q8FB16_ECOL6

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Protein
Submitted name:

2-oxoglutarate dehydrogenase E1 component

Gene

c5032

Organism
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: UniProtKB-EC
  2. thiamine pyrophosphate binding Source: InterPro

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Enzyme and pathway databases

BioCyciECOL199310:C5032-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
2-oxoglutarate dehydrogenase E1 componentImported (EC:1.2.4.2Imported)
Gene namesi
Ordered Locus Names:c5032Imported
OrganismiEscherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)Imported
Taxonomic identifieri199310 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000001410: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi199310.c5032.

Structurei

3D structure databases

ProteinModelPortaliQ8FB16.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000259588.
KOiK00164.
OMAiFPENFKP.
OrthoDBiEOG6V1M1F.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8FB16-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKISVFNCWY GLCSNAAVYD HQEKNMENMT SPGTLLSGDN ATWLEEYYQT
60 70 80 90 100
WLRTPEQLPE DWRRFFLSPE LTVQSVSGDN NVSGATLKKQ AAVIQLINAW
110 120 130 140 150
RTQGHLRAKL DPLGLNPPAD VPSLQPGFWG LSEEDLLQEF SVTFGAHTTQ
160 170 180 190 200
MPLKQLLNLL EQAWAGSQAY ELAHLENREE INWLLSRIES SNAPQADVQT
210 220 230 240 250
CIARFEKLMA AETLERYLHT RYVGQKRFSL EGGESAIPAL DTLTKRLRAQ
260 270 280 290 300
GVEEMVIGMA HRGRLNVLVN LLNKDPAQLF AEFEGKQTIG SGSGDVKYHM
310 320 330 340 350
GYSSNLETPA GSLHVALAYN PSHLEIVNPV VLGQVRARQE RRGEDGQAKV
360 370 380 390 400
VGVLIHGDSA LGGLGVNQTT FNLSQTQGYG TGGTLHLVIN NQIGFTTSRL
410 420 430 440 450
QDMRSSRYCT DIAKMVAAPI IHVNGDDVDA VCQVMELACE WRDTFRRDII
460 470 480 490 500
IDICCFRKHG HNESDEPRLT QPQMYQAVDA HPGTLARYGE SLARRGLLTQ
510 520 530 540 550
AQQDEMTARY RDWLDSCQKR EPQPLKPAIH SFSANWYGLT NPHWSAPVST
560 570 580 590 600
ALPRQKLAAY GEIISTLPPD VVAHPTIKRQ LALRQDMAAG TQPIDWGMAE
610 620 630 640 650
MLAYASLVDA GVGVRLSGED SGRGTFSHRH AVVHHQTEAR RYLPLQHIRA
660 670 680 690 700
GQASFDVYDS VLNEEALLAF EYGYSTSAPQ QLVIWEAQFG DFANGAQVAI
710 720 730 740 750
DQFISSGETK WDRYSGLTIL LPHGYDGQGP EHSSARPERW LQLCAENNMQ
760 770 780 790 800
VVMPSESAQM FHLLRGQALR PMRKPLVIMM SKRLLRFKGA MSELCEFTDG
810 820 830 840 850
AYKPVITDPQ LHQSQKVKRV ILCSGQVYYD VLEARKQREH EDEVAIVRLE
860 870 880 890 900
QLYPFPVAEL NDVLASWPNC CEWIWLQEEP ENQGAWRQIR HELAALKINT
910 920 930
PYWQYAGRPA AAAPATGYGR VHKQQIDEFL AAAFADIQP
Length:939
Mass (Da):105,209
Last modified:March 1, 2003 - v1
Checksum:i526504AC23ABBAF2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014075 Genomic DNA. Translation: AAN83458.1.
RefSeqiNP_756884.1. NC_004431.1.

Genome annotation databases

EnsemblBacteriaiAAN83458; AAN83458; c5032.
GeneIDi1039269.
KEGGiecc:c5032.
PATRICi18287756. VBIEscCol75197_4724.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014075 Genomic DNA. Translation: AAN83458.1 .
RefSeqi NP_756884.1. NC_004431.1.

3D structure databases

ProteinModelPortali Q8FB16.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 199310.c5032.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN83458 ; AAN83458 ; c5032 .
GeneIDi 1039269.
KEGGi ecc:c5032.
PATRICi 18287756. VBIEscCol75197_4724.

Phylogenomic databases

HOGENOMi HOG000259588.
KOi K00164.
OMAi FPENFKP.
OrthoDBi EOG6V1M1F.

Enzyme and pathway databases

BioCyci ECOL199310:C5032-MONOMER.

Family and domain databases

Gene3Di 3.40.50.970. 2 hits.
InterProi IPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view ]
PANTHERi PTHR23152. PTHR23152. 1 hit.
Pfami PF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view ]
PIRSFi PIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTi SM00861. Transket_pyr. 1 hit.
[Graphical view ]
SUPFAMi SSF52518. SSF52518. 2 hits.
TIGRFAMsi TIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CFT073 / ATCC 700928 / UPECImported.

Entry informationi

Entry nameiQ8FB16_ECOL6
AccessioniPrimary (citable) accession number: Q8FB16
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: October 1, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3